Randomized trial internal

J. Pildal, A. Hrobjartsson, K. J. Jorgensen, J. Hilden, D. G. Altman, and P. C. Gotzsche. Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials, Internal Journal of Epidemiology, 36, 4, 847-857, 2007. 

Malcolm R, Myrick H, Roberts J, et al The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial. J Gen Intern Med 17 349—355, 2002... 

O Connor PG, Carroll KM, Shi JM, et al Three methods of opioid detoxification in a primary care setting a randomized trial. Ann Intern Med 127 526-530, 1997 Oppenheimer E, Tobutt C, Taylor C, et al Death and survival in a cohort of heroin addicts from London clinics a 22-year follow-up study Addiction 89 1299—1308, 1994... 

Oncken CA, Hatsukami DK, Lupo VR, et al Effects of short-term use of nicotine gum in pregnant smokers. Clin Pharmacol Ther 59 654-61, 1996 Pomerleau OF, Pomerleau CS Neuroregulators and the reinforcement of smoking towards a biobehavioral explanation. Neurosci Biobehav Rev 8 503—513, 1984 Prochazka AV, Weaver MJ, Keller RT, et al A randomized trial of nortriptyline for smoking cessation. Arch Intern Med 158 2035-2039, 1998 Puska P, Korhonen HJ, Vartiainen E, et al Combined use of nicotine patch and gum compared with gum alone in smoking cessation a clinical trial in North Karelia. Tob Control 4 231-235, 1995... 

The effect of drug concentration expression on epinephrine dosing errors a randomized trial. Ann 37 Intern Med 2008 148 11-14. 

Failure of extracranial-intracranial arterial bypass to reduce the risk of ischemic stroke. Results of an international randomized trial. The EC/IC Bypass Study Group. N Engl J Med 1985 313 1191-1200. 

Aspirin in acute ischemic stroke has been studied in two large, randomized trials, the International Stroke Trial and the Chinese Acute Stroke Trial.20,21 Patients who received aspirin within 24 to... 

Crouse, J.R., Morgan, T., Terry, J.G., Ellis, J., Vitolins, M. and Burke, G.L. (1999). A randomized trial comparing the effect of caseine with that of soy protein containing varying amount of isoflavones on plasma concentration of lipids and lipoproteins, Arch. Intern. Med., 159, 2070-2076. 

The International Atomic Energy Agency is completing a large, randomized trial of the role of mitomycin in head and neck malignancies. Yale University continues to evaluated the possible superiority of porfiromycin (methyl mitomycin) in comparison to mitomycin in a randomized trial of greater than 120 HNC patients. Final results have yet to be published. 

Bunn PA, Lichter AS, Makuch RW, et al. Chemotherapy alone or chemotherapy with chest radiation therapy in limited small-cell lung cancer. A prospective, randomized trial. Ann Intern Med 1987 106 655-662. 

ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction ISIS-2. Lancet 1988 2 349-360. 

Altman DG, Schultz KF, Moher D, Egger M et al. for the CONSORT Group (2001) The revised CONSORT statement for reporting randomized trials explanation and elaboration Annals of Internal Medicine, 134, 663-694... 

MUler DH, Khan OA, Sheremata WA, Blumhardt LD et al., for the International Natalizumab Multiple Sclerosis Trial Group (2003) A controUed trial of natalizumab for relapsing multiple sclerosis New England Journal of Medicine, 348, 15-23 Moher D, Schulz KF and Altman DG (2001) The CONSORT statement Revised recommendations for improving the quahty of reports of paraUel-group randomized trials Annals of Internal Medicine, 134, 657-694... 

The definitive landmark trial that tested IM in patients with CML was the International Randomized trial of IFN-a and STI-571 (IRIS). In this study, 1106 patients, 553 in each arm, were randomized to receive IM at 400 mg daily or IFN-a with low-dose cytarabine. Crossover to the other arm of treatment was allowed for intolerance or lack of efficacy. The initial report with a median follow-up of 19 months showed an MCR... 

Escobar-Morreale HF, Botella-Carretero JI, Gomez-Bueno M, et al. Thyroid hormone replacement therapy in primary hypothyroidism a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone. Ann Intern Med. 2005 142 412-424. 

Carotid revascularization, initially by CEA, was introduced in early 1950s as a method to prevent stroke due to atherosclerosis of the carotid bifurcation and internal carotid artery (ICA). At least four prospective randomized trials have demonstrated... 

Henderson, J.M., Kutner, M.H., Millikan., W.J. jr., Gaiambos, J.T., Riepe, St.P., Brooks, W.S., Bryan, F.C., Warren, W.D. Endoscopic variceal sclerosis compared with distal splenorenal shunt to prevent recurrent variceal bleeding in cirrhosis. A prospective, randomized trial. Ann. Intern. Med. 1990 112 262-269... 

Imperiale, T.F., McCullough, A.J. Do corticosteroids reduce mortality from alcoholic hepatitis A meta-analysis of the randomized trials. Ann. Intern. Med. 1990 113 299 -307... 

Conant MA, Schacker TW, Murphy RL, Gold J, Crutchfield LT, Crooks RJ, Acebes LO, Aiuti F, Akil B, Anderson J, Melville RL, Ballesteros Martin J, Berry A, Weiner M, Black F, Anderson PL, Bockman W, Borelli S, Bradbeer CS, Braffman M, Brandon W, Clark R, Wisniewski T, Bruun JN, Burdge D, Caputo RM, Chateauvert M, LaLonde R, Chiodo F, et al. International Valaciclovir HSV Study Group. Valaciclovir versus aciclovir for Herpes simplex virus infection in HIV-infected individuals two randomized trials. Int J STD AIDS 2002 13(1) 12-21. 

EUis M, Spence D, de Pauw B, Meunier F, Marinus A, Collette L, Sylvester R, Meis J, Boogaerts M, SeUeslag D, Krcmety V, von Sinner W, MacDonald P, Doyen C, Vandercam B. An EORTC international multicenter randomized trial (EORTC number 19923) comparing two dosages of liposomal amphotericin B for treatment of invasive aspergillosis. Clin Infect Dis 1998 27(6) 1406-12. 

Wils JA, Bliss JM, Marty M, Coombes G, Fontaine C, Morvan F, Olmos T, Perez-Lopez FR, Vassilopoulos P, Woods E, Coombes RC. Epirubicin plus tamoxifen versus tamoxifen alone in node-positive postmenopausal patients with breast cancer a randomized trial of the International Collaborative Cancer Group. J Clin Oncol 1999 17(7) 1988-98. 

Winston DJ, Ho WG, Bruckner DA, Champlin RE. Beta-lactam antibiotic therapy in febrile granulocytopenic patients. A randomized trial comparing cefoperazone plus piperacillin, ceftazidime plus piperacillin, and imipe-nem alone. Ann Intern Med 1991 115(ll) 849-59. 

The IPPPSH Collaborative Group. Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol the International Prospective Primary Prevention Study in Hypertension (IPPPSH). J Hypertens I985 3(4) 379-92. 

Larsen RA, Leal MA, Chan LS. Fluconazole compared with amphotericin B plus flucytosine for cryptococcal meningitis in AIDS. A randomized trial. Ann Intern Med I990 II3(3) I83-7. 

Aylward PE, Wilcox RG, Horgan JH, White HD, Granger CB, Califf RM, Topol EJ. Relation of increased arterial blood pressure to mortahty and stroke in the context of contemporary thrombolytic therapy for acute myocardial infarction. A randomized trial. GUSTO-I Investigators. Ann Intern Med 1996 125(ll) 891-900. 

Wharton JM, Coleman DUWofsyCB, Luce JM, Blumenfeld W, Hadley WK,etal.Trimethoprim-sulfamethoxazole or pentamidine for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective randomized trial. Annals of internal medicine. 1986 Jul 105(1 ) 37-44. 

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