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Radicals 3-substituted

In contrast to the free radical substitution observed when halogens react with alkanes halogens normally react with alkenes by electrophilic addition... [Pg.254]

K. U. Ingold, Free Radical Substitution Reactions, Wiley-Interscience, New York, 1971. [Pg.233]

Substitution. In free-radical substitution, the olefin reacts with a free-radical source to form the allyl free radical, which in turn reacts with available reagent to produce both the final product and a new free radical. [Pg.436]

Toluene, an aLkylben2ene, has the chemistry typical of each example of this type of compound. However, the typical aromatic ring or alkene reactions are affected by the presence of the other group as a substituent. Except for hydrogenation and oxidation, the most important reactions involve either electrophilic substitution in the aromatic ring or free-radical substitution on the methyl group. Addition reactions to the double bonds of the ring and disproportionation of two toluene molecules to yield one molecule of benzene and one molecule of xylene also occur. [Pg.175]

Free-radical substitution of the side chain of toluene... [Pg.60]

Although some of the oxidative ring closures described above, e.g. reactions with lead tetraacetate (Section 4.03.4.1.2), may actually involve radical intermediates, little use has been made of this reaction type in the synthesis of five-membered rings with two or more heteroatoms. Radical intermediates involved in photochemical transformations are described in Section 4.03.9. Free radical substitutions are described in the various monograph chapters. [Pg.141]

These are discussed in (B-71MS4). Oxirane itself shows a strong molecular ion peak and a slightly stronger base peak at mje 29 (CHO ) due to isomerization to ethanal and loss of a methyl radical. Substituted oxiranes tend to show only weak molecular ion peaks, because of rearrangement and fragmentation. [Pg.99]

Radical substitution reactions by iodine are not practical because the abstraction of hydrogen from hydrocarbons by iodine is endothermic, even for stable radicals. The enthalpy of the overall reaction is also slightly endothermic. Thus, because of both the kinetic problem excluding a chain reaction and an unfavorable equilibrium constant for substitution, iodination cannot proceed by a radical-chain mechanism. [Pg.705]

Further evidence for a bromine-bridged radical comes from radical substitution of optically active 2-bromobutane. Most of the 2,3-dibromobutane which is formed is racemic, indicating that the stereogenic center is involved in the reaction. A bridged intermediate that can react at either carbon can explain the racemization. When the 3-deuterated reagent is used, it can be shown that the hydrogen (or deuterium) that is abstracted is replaced by bromine with retention of stereochemistry These results are also consistent with a bridged bromine radical. [Pg.709]

A review of Intramolecular Free Radical Substitution in Steroids by Chow-Wei Zan in Quart. Chinese Chem. Soc., 1-18, (1963), is available. It is, however, written in Chinese. [Pg.238]

Free-Radical Substitutions of Heteroaromatic Compounds R. O. C. Norman and G. K. Radda... [Pg.487]

In Volume 2, in the chapter on Free-Radical Substitutions of Heteroaromatic Compounds by R. O. C. Norman and G. K. Radda, p. 166, Table VI, 6-R-Acridine should read 9-R-Acridine p. 167, lines 17 and 18, 6-phenylacridine should read 9-phenyl-acridine... [Pg.433]

Free-radical substitutions of heterocyclic compounds have been carried out with alkyl, aryl, and hydroxyl radicals in solution and with halogen atoms in the gas phase. Of these, arylations have been the most extensively investigated. [Pg.131]

Qualitatively, the results shown in Tables IV and V indicate that the methyl radical, just as the phenyl radical, substitutes pyridine preferentially in the 2- and 4-positions. The absence of the 3-isomer in these reactions is probably a result of the method of analysis... [Pg.155]


See other pages where Radicals 3-substituted is mentioned: [Pg.255]    [Pg.85]    [Pg.465]    [Pg.290]    [Pg.523]    [Pg.703]    [Pg.703]    [Pg.705]    [Pg.707]    [Pg.131]    [Pg.135]    [Pg.137]    [Pg.139]    [Pg.143]    [Pg.145]    [Pg.149]    [Pg.151]    [Pg.153]    [Pg.155]    [Pg.157]    [Pg.160]    [Pg.161]    [Pg.163]    [Pg.167]   


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1.2.3- Triazine radical substitution

1.2.4- Triazoles radical substitution

4- phenyl-, radical substitution

5- Hexenyl radical methyl substituted

5-Hexenyl radical cyclization alkyl substituted

Addition Reactions of Radicals to Substituted Alkenes

Addition Reactions of Radicals with Substituted Alkenes

Addition-substitution, radical

Alkenes, -substituted, radical cations

Alkyl Substituted 5-Hexenyl Radicals

Alkyl radicals halo-substituted

Alkyl radicals halogen substituted

Alkyl radicals substituted

Alkyl-substituted amino radicals

Allylic Substitution and the Allyl Radical

Amino acids 3-substituted, enantioselective radical

And radical substitution

Aromatic Substitution Reactions Involving Radical Intermediates

Aromatic radical substitution

Aromatic substitution involving radical intermediates

Aryl halides radical nucleophilic substitution

Benzene radical substitution

Benzothiazole radical substitution

Benzyl radicals, substituted

Biaryls by radical substitution

Chlorination free-radical substitution

Cyclization substituted radicals

Diastereoselectivity, substituted anomeric radicals

Electrophilic aromatic substitution arene radical cations

Ester-substituted radicals

Free radical aromatic substitution

Free radical substitution

Free radical substitutions of heteroaromatic

Free radical substitutions of heteroaromatic compounds

Free radicals substituted

Free radicals substitution homolytic bimolecular reactions

Free radicals, stability substitution

Free-radicals substitution, definition

Halogen Substituted Hydrocarbon Radicals

Halogen, radical substitution

Halogen, substituted carbon-centered radical

Heteroaromatic compounds, free-radical substitutions

Hydrogen substitution reactions, radical-mediated

Imidazoles radical substitution

Indoles radical substitution

Intramolecular Aromatic Substitutions with Electrophilic -Radicals

Isoquinoline radical substitution

Isoquinolines radical substitution

Isotope effects radical aromatic substitution

K) for Addition of Substituted Propyl Radicals to (Meth)acrylate Esters

MINISCI Radical Aromatic Substitution

Norman, R. O. C., Radda, G. K., Free-Radical Substitution of Heteroaromatic

Nucleophilic Substitution of an Anodically Generated Radical Cation

Nucleophilic aromatic substitution radical

Nucleophilic aromatic substitution radical chain mechanism

Nucleophilic capture radical cation substitution

Nucleophilic substitutions, radical-mediated

Phenols radical substitution

Phenyl radicals aromatic substitution

Phenyl radicals, reactions rates with substituted

Photo-stimulated radical substitution

Photoinduced radical reactions nucleophilic aromatic substitution

Pyrazine radical substitution

Pyridazine radical substitution

Pyridine radical substitution

Pyridines radical substitution, regioselectivity

Pyrimidines radical substitution

Pyrrole 1-methyl-, radical substitution

Pyrroles radical substitution

Quinoline 2- methyl-, radical substitution

Quinoline radical substitution

Quinolines 2- methyl-, radical substitution

Radical Reactions of Aromatic Compounds with Captodative Substitution

Radical Substitution Reaction Mechanisms

Radical Substitution Reactions (EOB)

Radical Substitution Reactions at the Saturated C Atom

Radical Substitution Reactions at the Tetrahedral Carbon Atom

Radical Substitution at Carbon

Radical Substitution of Benzylic and Allylic Hydrogens

Radical Substitution of Hydrogen by Anodically Generated Radicals

Radical aliphatic substitution

Radical allylic substitution

Radical anion substitution reactions

Radical aromatic substitution relative rates

Radical cations para-substituted anilines

Radical cations substitution

Radical chain reactions substitution

Radical chain substitution mechanism

Radical dialkoxy-substituted

Radical homolytic aromatic substitutions

Radical polymerization substitution

Radical reaction substitution

Radical reactions aromatic substitution

Radical reactions, domino processes substitution

Radical substitution autoxidation

Radical substitution definition

Radical substitution deuteration

Radical substitution halogenation

Radical substitution methods

Radical substitution reactions halogenation

Radical substitution reactions rates

Radical substitution reactions stereochemistry

Radical substitution, heteroaromatic

Radical substitution, heteroaromatic systems

Radical substitution, orientation

Radical-nucleophilic aromatic substitution carbanions

Radical-nucleophilic aromatic substitution electron transfer

Radical-nucleophilic aromatic substitution experiments

Radical-nucleophilic aromatic substitution halides

Radical-nucleophilic aromatic substitution heterocyclic synthesis

Radical-nucleophilic aromatic substitution initiation step

Radical-nucleophilic aromatic substitution intermolecular

Radical-nucleophilic aromatic substitution intramolecular

Radical-nucleophilic aromatic substitution propagation steps

Radicals carbonyl-substituted

Radicals chain nucleophilic substitutions

Radicals ether-substituted

Radicals hetero-substituted

Radicals in aromatic substitution

Radicals multiple halogen substitution

Radicals substitution reactions with hydrocarbons

Radicals substitutive-type nomenclature

Radicals, reduction substitution

Relative Rates for Addition of Substituted Propyl Radicals to AN andS

Selective radical bromination allylic substitution of H by Br

Some mechanisms of electrophilic and radical substitution reactions

Stannanes radical substitution reactions

Stereoselectivity ester-substituted radicals

Substituted Alkyl Radical Clocks

Substituted Allyl Radicals

Substituted Vinyl Radicals

Substituted amino radicals

Substituted amino radicals reactions

Substituted amino radicals sources

Substituted radical anions

Substitution SrnI , radical-nucleophile unimolecular

Substitution mechanism, acidic radicals

Substitution radical

Substitution radical

Substitution radical mediated

Substitution radical nucleophilic

Substitution radical, mechanism

Substitution reactions free radical

Substitution reactions radical cations

Substitution reactions, radical-mediated

Substitution reactions, radical-mediated brominations

Substitution, radical allylic bromination

Substitution, radical first order kinetics

Substitution, radical leaving group effects

Substitution, radical nucleophilic, unimolecular

Substitution, radical nucleophilic, unimolecular mechanism

Substitution, radical nucleophilic, unimolecular reactions

Substitution, radical solvent effects

Substitution, radical substrate effects

Substitutions Involving Aryl Free Radicals

Substitutions Involving Aryl Radicals

Substitutions of Heteroaromatic Bases by Nucleophilic Carbon Free Radicals

Summary of radical substitution reactions

Synthetically useful radical substitution reaction

Thiatriazoles Substituted with C-Radicals

Thioether substituted radical

Thiophenes radical substitution

Tris -substituted radicals, reactions

Use of Alkoxy-Substituted Anomeric Radicals

Vinyl-substituted monomers radical ring-opening

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