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Radical alkylation

Anion radical Alkyl radical Halide anion... [Pg.590]

Guanine, 9-/3-D-ribofuranosyl-, 5, 536 Guanine, 6-thio-tautomerism, 5, 509 toxicity, 1, 141 Guanine, 8-trifluoromethyl-synthesis, 5, 574 Guanines, thio-synthesis, 5, 572 Guanosine arylation, 5, 538 dipole moment, 5, 522 free radical alkylation, 5, 543 hydrobromide... [Pg.642]

UV spectra, 5, 517 bromination, 5, 540 dipole moment, 5, 523 free radical alkylation, 5, 543 free radical methylation, 5, 544 IR spectra, 5, 518, 519 irradiation, 5, 543 mass spectra, 5, 519 metabolism, 1, 234 monoprotonated tautomerism, 5, 509 oxidation, 5, 539 1-oxides... [Pg.646]

Imidazo[4,5-c]pyridine, 2,3-dimethyl-radical alkylation, 5, 621 Imidazo[4,5-c]pyridine, 2-ethoxy-synthesis, 5, 635... [Pg.661]

Beyer synthesis, 2, 474 electrolytic oxidation, 2, 325 7r-electron density calculations, 2, 316 1-electron reduction, 2, 282, 283 electrophilic halogenation, 2, 49 electrophilic substitution, 2, 49 Emmert reaction, 2, 276 food preservative, 1,411 free radical acylation, 2, 298 free radical alkylation, 2, 45, 295 free radical amidation, 2, 299 free radical arylation, 2, 295 Friedel-Crafts reactions, 2, 208 Friedlander synthesis, 2, 70, 443 fluorination, 2, 199 halogenation, 2, 40 hydrogenation, 2, 45, 284-285, 327 hydrogen-deuterium exchange, 2, 196, 286 hydroxylation, 2, 325 iodination, 2, 202, 320 ionization constants, 2, 172 IR spectra, 2, 18 lithiation, 2, 267... [Pg.831]

Quinolinium 2-dicyanomethylene-1,1,3,3-tetracyanopropanediide dimensions, 2, 110 Quinolinium iodide, 1-alkyl-Ladenburg rearrangement, 2, 300 Quinolinium iodide, 1-methyl-Ladenburg rearrangement, 2, 300, 335 Quinolinium iodide, [l-methyl-4-[3(5)-pyrazolyl]-blood sugar level and, 5, 291 Quinolinium perchlorate, 1-ethoxy-hydroxymethylation, 2, 300 Quinolinium perchlorate, 1-methyl-nitration, 2, 318 Quinolinium salts alkylation, 2, 293 Beyer synthesis, 2, 474 electrophilic substitution, 2, 317 free radical alkylation, 2, 45 nitration, 2, 188 reactions... [Pg.832]

Goldschmidt and Minsinger " isolated some of the products formed during the decomposition of several diacyl peroxides in pyridine (Table IV). The yields obtained are so far the highest reported for any free-radical alkylation. [Pg.154]

The development of the autoxidation theory, in which the propagating radicals, alkyl, and alkylperoxyl (R ROO ), and the hydroperoxide (ROOH) are the key intermediates, has therefore led to a comprehensive theory of antioxidant action Scheme 2 shows the two major... [Pg.105]

In this section wc consider the properties and reactions of three classes of carbon-centered radicals alkyl radicals (3.4. l.l), aryl radicals (3.4.1,2) and acyl radicals (3.4.1.3). [Pg.112]

FREE-RADICAL ALKYLATION OF QUINONES 2-PHENOXYMETHYL-l,4-BENZOQUINONE... [Pg.68]

The reaction is a free-radical alkylation in which radicals are derived from a carboxylic acid by decarboxylation with Ag+/S20a-. If has the advantage that the reaction medium can be adjusted so that the monoalkylatcd product precipitates as it is formed, whereby di- or polyalkylation5 is suppressed. [Pg.71]

The radical alkylation of ketones is achieved by their conversion into the desired N-silyloxy enamines 81 (Scheme 13). The reaction of 81 with diethyl bromomalonate in the presence of EtsB (0.5 equiv) in benzene was performed in open air and stirred at room temperature for 3h. With nitro compounds it is achieved by their conversion into the desired ]V-bis(silyloxy)enamines (82) (Scheme 13). When the reaction is carried out with 82 and alkyl iodides with an electron-withdrawing substituent at the a-position, using V-70 as radical initiator (2,2 -azobis(4-methoxy-2,4-dimethylvaleronitrile)), it underwent a clean radical alkylation reaction to yield an oxime ether. Successful radical alkylation of... [Pg.150]

Even more pronounced steric effects have been observed for the free radical alkylation of protonated N-heterocyclic bases by the procedure of Minisci69, b d. Quinoline is attacked selectively in the 2- and 4-position by nucleophilic alkyl radicals in sulfuric acid. The largest radicals, t.-butyl, react exclusively in the 2-position because of steric hindrance by the peri-hydrogen when attack occurs at the 4-position. [Pg.26]

A Sml2-induced reductive cyclization of (V-(alkylketo)pyrroles provided an entry into medium ring 1,2-annelated pyrroles <06EJO4989>. An oxidative radical alkylation of pyrroles with xanthates promoted by triethylborane provided access to a-(pyrrol-2-yl)carboxylic acid derivatives <06TL2517>. An oxidative coupling of pyrroles promoted by a hypervalent iodine(III) reagent provided bipyrroles directly <060L2007>. [Pg.147]

Methyl-l,2,4-triazole 37 undergoes radical alkylation to give monoalkylated 1-methyl-1,2,-4-triazoles 48a-e in which the new substituent is in the 5-position no addition products resulting from alkylation in the 3-position were observed (Equation 14 and Table 3) <2001TL7353>. [Pg.167]

Evidently, the activation energy for a thermally neutral reaction with participation of a hydrogen atom or a radical (alkyl, alkoxyl, etc.) is higher in these cases where there is a iT-bond or an aromatic ring adjacent to the attacked C—H bond. This effect is a property of the structures themselves, and the n-bond exerts a dual effect on the reaction center. On the one hand, by weakening the C—H bond the ir-bond in the a-position lowers the enthalpy... [Pg.258]

A. Behavior of BENA in Radical Reactions Until recently, data on the behavior of BENAs in radical reactions have been lacking in the literature. However, several successive approaches to radical alkylation of BENA at the (3-C atom have been recently developed by Korean researchers (527). [Pg.691]

It was demonstrated (527) that radical alkylation of BENAs can be performed in the absence of totic organotin compounds (Scheme 3.259). [Pg.694]

A typical atom transfer sensitization process is shown in Figure 3.7 the alkylation of an unsaturated acid via a radical produced from an alcohol by hydrogen abstraction (in a green solvent, water). This principle has been applied to a large series of radical alkylation reactions, where the radical precursor is an alcohol, an ether, or even an alkane. ... [Pg.70]

More recently, Kim and coworkers have developed a novel radical alkylation reaction of organic nitro derivatives 16a-d via bis(silyloxy)enamines 17a-d (Scheme 16). This method enables not only P -alkylation to the nitro gronp, bnt also the conversion of the nitro group (16a-d) into an oxime ether fnnctionahty (18a-d). The irradiation of a solntion of 16a-d with iodomethyl phenyl snlfone (or ethyl iodoacetate) and hexamethylditin in benzene at 300 nm give the oxime ethers 18a-d in good yields. [Pg.172]

Even more pronounced steric effects have been observed for the free radical alkylation of protonated N-heterocyclic bases by the procedure of Minisci ... [Pg.29]


See other pages where Radical alkylation is mentioned: [Pg.91]    [Pg.510]    [Pg.511]    [Pg.512]    [Pg.538]    [Pg.573]    [Pg.656]    [Pg.680]    [Pg.760]    [Pg.790]    [Pg.858]    [Pg.873]    [Pg.390]    [Pg.599]    [Pg.69]    [Pg.71]    [Pg.645]    [Pg.711]    [Pg.963]    [Pg.645]    [Pg.148]    [Pg.65]    [Pg.314]    [Pg.178]    [Pg.321]    [Pg.70]   
See also in sourсe #XX -- [ Pg.1273 ]

See also in sourсe #XX -- [ Pg.159 ]

See also in sourсe #XX -- [ Pg.333 ]




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1- Alkylimidazoles, reaction with alkyl radicals

5-Hexenyl radical cyclization alkyl substituted

A-hydroxy alkyl radicals

Activation energy alkyl radical -scission

Addition reactions, equilibria and alkyl radical heats of formation

Alkanes from alkyl radicals

Alkoxy radicals from alkyl hydroperoxides

Alkyl Radical Clocks

Alkyl Substituted 5-Hexenyl Radicals

Alkyl and Acyl Radicals

Alkyl azides radical cyclizations

Alkyl benzenes under radical conditions

Alkyl cyanides radical

Alkyl formates, radical

Alkyl formates, radical reactions

Alkyl free radicals

Alkyl free radicals hyperconjugation

Alkyl groups free radicals

Alkyl groups in free radicals

Alkyl halide radical propagation

Alkyl halides aromatic anion radical reduction

Alkyl halides radical dehalogenation

Alkyl halides radical, cobalt-mediated

Alkyl halides radicals

Alkyl iodides atom transfer radical

Alkyl iodides, intermolecular radical

Alkyl iodides, intermolecular radical addition

Alkyl nitrates hydroxyl radical reactions

Alkyl nitronates radical cyclization

Alkyl peroxide radical

Alkyl peroxo radical

Alkyl peroxy radical reactivity

Alkyl peroxy radical reactivity compounds

Alkyl peroxy radicals

Alkyl peroxy radicals, atmosphere

Alkyl peroxyl free radicals

Alkyl peroxyl radicals

Alkyl peroxyl radicals traps

Alkyl radical addition

Alkyl radical addition-cyclization

Alkyl radical additions to double and triple bonds

Alkyl radical cyclization

Alkyl radical decomposition

Alkyl radical decomposition models

Alkyl radical decomposition oxidation

Alkyl radical disproportionation

Alkyl radical dissociations

Alkyl radical fluorinated derivative

Alkyl radical initiation

Alkyl radical intermediates, evidence

Alkyl radical intramolecular hydrogen abstraction

Alkyl radical primary

Alkyl radical secondary

Alkyl radical tertiary

Alkyl radical traps

Alkyl radical with poly

Alkyl radical with silicon hydride

Alkyl radical with silicon surface

Alkyl radical with thiols

Alkyl radical, 127 silicon hydride

Alkyl radical, Hunsdiecker reaction

Alkyl radical-anions

Alkyl radicals

Alkyl radicals

Alkyl radicals Structure

Alkyl radicals carbocycle formation via cyclization

Alkyl radicals compared

Alkyl radicals disproportionation pathways

Alkyl radicals from diacyl peroxides

Alkyl radicals from fragmentation

Alkyl radicals from xanthates

Alkyl radicals geometries

Alkyl radicals group

Alkyl radicals halo-substituted

Alkyl radicals halogen substituted

Alkyl radicals heterocyclic formation

Alkyl radicals heterolytic fragmentation

Alkyl radicals hydrogen abstraction

Alkyl radicals iodides

Alkyl radicals ionization potentials

Alkyl radicals large

Alkyl radicals nucleophilic character

Alkyl radicals nucleophilicity

Alkyl radicals oxidation

Alkyl radicals oxidative cleavage

Alkyl radicals preferential formation

Alkyl radicals radical reactions

Alkyl radicals rate constant

Alkyl radicals regeneration

Alkyl radicals relative selectivities

Alkyl radicals review)

Alkyl radicals small

Alkyl radicals sources

Alkyl radicals stability

Alkyl radicals substituted

Alkyl radicals, atmosphere

Alkyl radicals, chemically activated

Alkyl radicals, conjugate addition

Alkyl radicals, dichlororadical cyclizations

Alkyl radicals, disproportionation rearrangements

Alkyl radicals, disproportionation recombination

Alkyl radicals, generation

Alkyl radicals, photolytic

Alkyl radicals, photolytic generation

Alkyl radicals, reactivity

Alkyl radicals, reduction potentials

Alkyl radicals, scavenging

Alkyl radicals, secondary, irradiated

Alkyl radicals, table of names

Alkyl-amino radicals

Alkyl-substituted amino radicals

Alkylation by free-radicals

Alkylation of Nitro Compounds via Alkyl Radicals

Alkylation xanthate-mediated radical

Alkylations radical

Alkylations radical, isoquinoline

Alkylations with Alkyl Radicals

Allene reaction + alkyl radicals

Alpha- alkyl radical

An alternative way of making alkyl radicals the mercury method

Aromatic compounds, fused radical alkylation

Aryl telluroformates as precursors of oxyacyl and alkyl radicals

Benzene, alkyloxidative degradation via alkyl radical addition

Boron Alkyls and Metal Alkyl Initiators of Free-Radical Polymerizations

Boron and metal alkyl initiators of free-radical polymerizations

By Alkyl Radicals

Carbon-centered alkyl radicals

Carbon-centered alkyl radicals reaction with

Chain alkyl radicals

Cyclization of alkyl radicals

Cyclopropane, keto vinylfree radical 1,6-addition reactions alkyl boranes

Desilylative radical alkylation

Disproportionation, of alkyl radicals

Electron spin resonance alkyl radical

Emission of alkyl radicals from disordered selenium surface

Fluorinated alkyl radicals

Free radical polymerization, alkyl vinyl

Free radical polymerization, alkyl vinyl ethers

Free radical stabilization by alkyl groups

Free radicals detection, alkyl

Free-radicals alkylation

Free-radicals alkylation, rates

Halides, alkyl from radical halogenation

Halogenated alkyl radical additions to double and triple bonds

Heterocycles, acylation radical alkylation

High-energy processes alkyl radicals

Homolysis of alkyl radicals

Hydroxamates, O-acyl thiocarboxyl radicals from alkyl 2-pyridyl sulfides

Hydroxy radicals from alkyl hydroperoxides

Imidazoles reaction with alkyl radicals

Intramolecular radical-induced alkylation

Mechanism, radical with alkyl halides

Metal-alkyl radical combination reactions

Minisci radical alkylation

Nitroxide with alkyl radicals, reaction

Oxidation Reactions of Alkyl Radicals

Oxidation Reactions of Higher Alkyl Radicals

Oxidation, of alkyl radicals by copper

Oxime ethers alkyl radical addition

Oxygen reaction with alkyl radicals

Paramagnetic Relaxation of the Alkyl Radical

Peroxides with alkyl radicals

Peroxy alkyl radicals transfer reaction

Peroxy alkyl radicals, fragmentation

Phenylsulfonyl oxime ethers, alkyl radical

Phenylsulfonyl oxime ethers, alkyl radical additions

Powder EPR Spectra of Alkyl Radicals

Preparation of polyalkylsiloxanes with higher alkyl radicals at the silicon atom and varnishes based on them

Preparing Alkyl Halides from Alkanes Radical Halogenation

Primary Alkyl Radicals and Free-Radical Clock Methodology

Primary alkyl radical spin trapping

Pyridines reactions with alkyl radicals

Pyridinium salts reactions with alkyl radicals

Pyrimidines radical alkylation

Quinaldine reaction with alkyl radicals

Quinoline reaction with alkyl radicals

Radical addition of alkyl radicals

Radical decarboxylative alkylation

Radical ions alkylation reactions

Radical mechanism, addition with alkyl halides

Radical mechanisms alkyls

Radical metal alkyl decomposition

Radical reactions reductive alkylation

Radical stereoselectivity reductive alkylation

Radical synthons alkyl

Radical-cations from arenes alkylation

Radicals 3-acyloxy)alkyl

Radicals alkyl radical

Radicals alkylic

Radicals halogen containing alkyl

Radicals phosphatoxy)alkyl

Radicals tandem with alkylation

Radicals, coupling reactions with alkyl halides

Radicals, from alkyl halides

Reaction Mechanism for Alkyl Radical Formation

Reaction with alkyl radicals

Reactions of Alkyl Radicals

Reactions with Alkyl and Thiyl Radicals

Recombination of Alkyl Radicals

Regeneration of alkyl radicals

Resonance energy alkyl free radicals

STABILITIES OF ALKYL RADICALS

Secondary alkyl free radical

Simple Alkyl Radicals

Spatial Distribution of the Alkyl Radical

Structure of Alkyl Radicals Hyperconjugation

Substituted Alkyl Radical Clocks

Sulfonylation, alkyl radicals

Tandem Radical Cyclizations and Alkylations

The Geometry of Alkyl Radicals

The reaction of alkyl radicals with

Thiophenes 2- radical intramolecular alkylations

Trialkylborane, alkyl radical precursor

Tris silane with alkyl radical

Vinyl group, alkyl radical stabilization

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