Quick identity test

B- GltSFECTlU RAMAN AlKANC22. o S Peak Table Raman Peak Picking 

Wavenunber 1 Abs. IntensRv 1 Ret. Intendtv 1 Width 1 Found f Threshold I Shotdder I  

The Quick Identity Test offers a user-friendly method to judge the similarity of two spectra. This method requires a reference spectrum of the substance of interest. The test determines the Euclidean distance between the test and the reference spectra. 

Enter the reference spectrum in the field Principal File for Quick Identity Test, and the files to be tested in the field File(s) for Quick Ident of the Selected Files page of the dialog box (Fig. 11.21). 

Selected Files Frequency Ranges Data FVepiocessing  

---

Curve Eit A Integration Eeak Picking Quick Identity Test A Spectrum Search 3b Library Editor Library Browser... 

Figure 11.21. The Quick Identity Test dialog box Selected Files page.

The following information is of relevance when you apply the Quick Identity Test ... 

FT-Raman is another technique by which quick and easy identity testing can be performed. A FT-Raman method has been developed to identify the two active components (tegafur and uracil) in formulated capsules (48). Figure 5 displays a spectral region where Raman bands unique to uracil and tegafur can be found in the FT-Raman spectrum of an intact capsule. These bands allow the analyst to confirm that both components are present in the formulated product. Raman spectroscopy has become an essential chemical and physical identification... 

From an isotherm test it can be determined whether a particular organic material can be removed effectively. It will also show the approximate capacity of the carbon for the application and provide a rough estimate of the carbon dosage required. Isotherm tests also afford a convenient means of studying the effects of pH and temperature on adsorption. Isotherms put a large amount of data into concise form for ready evaluation and interpretation. Isotherms obtained under identical conditions using the same contaminated groundwater for two or more carbons can be quickly and conveniently compared to determine the relative merits of the carbons. 

The test solution prepared as specified, is placed in the wide-mouthed bottle, 1 g of KI (AsT) and 10 g of Zn (AsT) are added, and the prepared glass tube is placed quickly in position. The reaction is allowed to proceed for 40 minutes. The yellow stain that is produced on the HgCl2 paper if As is present is compared by daylight with the standard stains obtained by performing in an identical manner with known quantities of dilute arsenic solution (AsT). The comparison of the stains is made immediately at the completion of the test. 

Chemical analysis of the plant material can often be of assistance to the plant taxonomist. Cases of doubtful identity can sometimes be resolved. For example, the various species of Alyssum are rather similar morphologically. A simple col-ourimetric test of herbarium material can quickly confirm, or deny a given classification by the taxonomist. 

Small quantities of phosphorus may be estimated quickly by the molybdate method, the amount of phosphomolybdate being estimated colorimetrieally by comparison in Nessler glasses or test-tubes with a standard prepared under conditions which are made identical as far as possible. An account of this estimation is given under Phosphoric Acid, p. 182. 

This steel roller is placed quickly on the anvil of the drop test equipment. An identical roller is placed on top of it. 

HPLC methods are preferred if excipients would interfere, if nonspecific detection techniques (mainly in UV) would be used, or when multiple APIs (combination product) are present in a drug product. Since dissolution sample set analysis can be very long due to six samples per bath as well as multiple time points for prohle testing, fast run times are preferred to quickly determine the results. If a fast HPLC method for CU is available, then the identical HPLC method can be utilized for dissolution analysis. 

A common problem is to compare two or more sets of data. For example, a new analytical method may be assessed by analyzing a test material using the new and an established method. The means of a number of replicate measurement results obtained by each method will not be identical, but within the experimental uncertainty is there a significant difference The preferred method is to use analysis of variance (ANOYA) which can accommodate a number of variables and different numbers of data (see chapter 4). However, a quick test for two means can be performed by calculating a /-statistic and its associated probability. 

---