Quadrupole linear ion trap mass spectrometers

Hopfgartner, G. Varesio, E. Tschappat, V. Grivet, C. Emmanuel Bourgogne, E. Leuthold, L. A. Triple quadrupole linear ion trap mass spectrometer for the analysis of small molecules and macromolecules. J. Mass Spectrom. 2004, 39, 845-855. [Pg.61]

Hopfgartner, G. Husser, C. Zell, M. Rapid screening and characterization of drug metabolites using a new quadrupole-linear ion trap mass spectrometer. J Mass Spectrom 2003, 38, 138-150. [Pg.421]

Williamson, B. L., Marchese, J., and Morrice, N. A. (2006). Automated identification and quantification of protein phosphorylation sites by LC/MS on a hybrid triple quadrupole linear ion trap mass spectrometer. Mol. Cell. Proteomics 5 337-346. [Pg.221]

Thomas, A., Hopfgartner, G., Giroud, C., and Staub, C. (2009). Quantitative and qualitative profiling of endocannabinoids in human plasma using a triple quadrupole linear ion trap mass spectrometer with liquid chromatography. Rapid Commun. Mass Spectrom. 23, 629—638. [Pg.55]

Marquet, P., Saint-Marcoux, F., Gamble, T.N., Leblanc, J.C. (2003). Comparison of a preliminary procedure for the general unknown screening of drugs and toxic compounds using a quadrupole-linear ion-trap mass spectrometer with a liquid chromatography-mass spectrometry reference technique. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 789(1) 9-18. [Pg.221]

Shou, W.Z. et al., A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer, J. Mass Spectrom., 40(10), 1347, 2005. [Pg.31]

Xia, Y.Q. et al., Use of a quadrupole linear ion trap mass spectrometer in metabolite identification and bioanalysis, Rapid Commun. Mass Spectrom., 17(11), 1137, 2003. [Pg.202]

Sierra Analytics and Applied Biosystems investigated the metabolic profile of indinavir, an HIV protease inhibitor with a very short half-life (2 hours), readily metabolised via CYPs to produce phase I and subsequent II products. Aliquots (10 pL) of indinavir incubated with rat liver S9 fractions were separated by online liquid chromatography and analysed with an Applied Biosystems hybrid triple quadrupole/linear ion trap mass spectrometer in information dependent acquisition (IDA) mode. This consisted of an enhanced MS survey scan followed by enhanced product ion scans for the two most intense parent ions as dependent MS/MS experiments. [Pg.301]

Hybrid quadrupole linear ion-trap mass spectrometer... [Pg.4364]

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