Inductively coupled plasma mass quadrupole

Q-ICPMS quadrupole inductively coupled plasma mass spectrometry... 

Table 4 Typical Detection Limits Using a Quadrupole Inductively Coupled Plasma Mass Spectrometer (ICP-MS)a...

MEASUREMENT OF TOTAL Se AND Se SPECIES IN SEAFOOD BY QUADRUPOLE INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY, ELECTROTHERMAL ATOMIZATION ATOMIC ABSORPTION SPECTROMETRY, AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY... 

ETA-AAS, Electrothermal Atomization Atomic Absorption Spectrometry FAAS, Flame Atomic Absorption Spectrometry HG-AAS, Hydride Generation Atomic Absorption Spectrometry ICP-AES, Inductively Coupled Plasma Atomic Emission Spectrometry ID-MS, Isotopic Dilution Mass Spectrometry NAA, Neutron Activation Analysis Q-ICP-MS, Quadrupole Inductively Coupled Plasma Mass Spectrometry SS-Z-ETA-AAS, Solid Sampling Zeeman Atomic Absorption Spectrometry Z-ETA-AAS, Zeeman Electrothermal Atomization Atomic Absorption Spectrometry... 

Lopes C. M.P.V., Almeida A.A, Liicia M.M.F.S., Lima J.L.F.C. Determination of Rh, Pd and Pt in urine samples using a pre-concentration sequential injection analysis system coupled to a quadrupole-inductively coupled plasma-mass spectrometer. Analytica Chimica Acta 2007 600 226-232. 

Alsenz H, Zereini F, Wiseman C, Piittmann W (2009) Determination of palladium in airborne particulate matter using isotope dilution-quadrupole-inductively coupled plasma-mass spectrometry (ID-Q-ICP-MS) with helium as a collision gas after reductive co-precipitation with mercury. Anal Bioanal Chem 395 1919-1927 Alt F, Bambauer A, Hoppstock K, Mergler B, Tdlg G (1993) Platinum traces in airborne particulate matter. Determination of whole content, particle size distribution and soluble platinum. Fresenius J Anal Chem 346 693-696... 

TIMS, depending on the application [3]. These developments with magnetic sector instruments include multiple Faraday cup detectors (multicollectors) and multiple ion counters. The Faraday cup multicollectors have enabled the determination of isotope ratios with accuracy and precision rivaling TIMS [4], Due to lower sensitivity and differences in instrument design, quadrupole instruments (quadrupole inductively coupled plasma mass spectrometry [Q-ICP-MS]) have not demonstrated the same accuracy and precision as magnetic sector instruments, especially at low concentrations [5], Nevertheless, improvements in the sensitivity of quadrupole instrumentation have also increased their utility for many isotope ratio applications [6]. 

DTlio, S., Violante, N., Senofonte, O. et al. (2010). Determination of depleted uranium in human hair by quadrupole inductively coupled plasma mass spectrometry Method development and validation, A a/. Methods 2, 1184-1190. 

Allen, L. A., Leach, J.J., Pang, H. M., and Houk, R. S. (1997). Precise measurement of ion ratios in solid samples using laser ablation with a twin quadrupole inductively coupled plasma mass spectrometer.J. Anal. At. Spectrom. 12(2), 171. 

Gunther, D., Longerich, H. P., and Jackson III, S. E., (1995). A new enhanced sensitivity quadrupole inductively coupled plasma-mass spectrometer (ICP-MS). Can.J.Appl. Spec-Irosc. 40(4)... 

MuThiz, C. S., Marchante-Gayon,J. M., Alonso, J. 1. G., and Sanz-Medel, A. (1998). Comparison of electrothermal atomic absorption spectrometry, quadrupole inductively coupled plasma mass spectrometry and double-focusing sector field inductively coupled plasma mass spectrometry for the determination of aluminium in human serum.J. Anal. At. Spectrom. 13(4), 283. 

Weiss, D, Boyle, E. A., Chavagnac,V, Herwegh, M., and Wu, J. (2000). Determination of lead isotope ratios in seawater by quadrupole inductively coupled plasma mass spectrometry after Mg(OH)2 co- precipitation. Spectrochim.Acta, Part B 55(4), 363-374. 

Cremers, D.A. Radziemski, L.J. 2006. Handbook of Laser Induced Breakdown Spectroscop. J. Wiley Sons, New York Gonzalez, J., Oropeza, D., Mao, X.L., Russo, R.E. 2008. Assessment of the precision and accuracy of thorium (232Th) and uranium (238U) measured by quadrupole based-inductively coupled plasma-mass spectrometry comparison of liquid... 

Koirtyohann SR (1994) Precise determination of isotopic-ratios for some biologically significant elements by inductively-coupled plasma-mass spectrometry. Spectrochim Acta B-Atomic Spectrosc 49 1305-1311 Rosier J, Kucera M, Sylvester P (2001) Precise measurement of Li isotopes in planktonic foraminiferal tests by quadrupole ICPMS. Chem Geol 181 169-179... 

M. Vazquez Pelaez, J. M. Costa-Fernandez and A. Sanz-Medel, Critical comparison between quadrupole and time-of-flight inductively coupled plasma mass spectrometers for isotope ratio measurements in elemental speciation, J. Anal. At. Spectrom., 17, 2002, 950-957. 

Multi-element determination of dissolved metals at ultratrace level may be performed by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). U.S. EPA s Methods 200.8 and 1638 present a methodology for measuring trace elements in waters and wastes by the above technique. Sample is acid digested and the solution is introduced by pneumatic nebulization into a radio-frequency plasma. The elements in the compounds are atomized and ionized. The ions are extracted from the plasma through a differentially pumped vacuum interface and separated by a quadrupole mass spectrometer by their mass to charge ratios. The mass spectrometer must have a resolution capability of 1 amu peak width at 5% peak height. 

Figure 11 Inductively coupled plasma mass spectra of (a) thorium demonstrates the propensity for metal oxide formation in the quadrupole ion trap. Cryogenic pumping (b) reduces the residual gases, resulting in dramatically reduced oxide formation. (From Ref. 50.)...

Figure 1 Schematic diagram of a typical commercial inductively coupled plasma mass spectrometry (ICP-MS) instrument (A) liquid sample, (B) peristaltic pump, (C) nebulizer, (D) spray chamber, (E) argon gas inlets, (F) load coil, (G) sampler cone, (H) skimmer cone, (I) ion lenses, (J) quadrupole, (K) electron multiplier detector, (L) computer.

Other elements were measured by a Perkin-Elmer SCIEX ELAN 6100 DRCII Inductively Coupled Plasma Mass Spectrometry (ICP-MS) instrument equipped with a cyclonic spray chamber, a concentric nebulizer and a dynamic reaction cell (DRC). In the vented (standard) mode, no reaction gas is present in the cell and the instrument shows the typical characteristics of a quadrupole-based ICP-MS apparatus. When the gas is introduced into the cell an ion-molecule reaction takes place that can be tailored so as to eliminate spectroscopic interferences. Experimental conditions are summarized in Table 10.2. 

M. Krachler, A. Alimonti, F. Petrucci, K. J. Irgoli , F. Forestiere, S. Caroli, Analytical problems in the determination of platinum-group metals in urine by quadrupole and magnetic sector E>eld inductively coupled plasma mass spectrometry, Anal. Chim. Acta, 363 (1998), ID 10. 

Inductively coupled plasma mass spectrometry (ICP-MS) is one of the most significant analytical advances to occur in the last 20 years as it allows multielement analysis of solutions and solids to be performed at subnanogram concentrations. Instrumental advances have occurred such that Quadrupole (Q) ICP-MS units are now in routine use in many laboratories. In this chapter, the use of Q-ICP-MS and high performance liquid chromatography (HPLC)-ICP-MS is discussed as regards the quantification of total As and As species in seafood. To highlight the strengths and weaknesses of the use of ICP-MS, data are used that were mainly produced in the laboratories of the authors of this chapter. 

I. Rodushkin, T. Ruth, D. Klockare, Non-spectral interferences caused by a saline water matrix in quadrupole and high resolution inductively coupled plasma mass spectrometry, J. Anal. Atom. Spectrom., 13 (1998), 159-166. 

Smith, C.J., Wilson, I.D., Abou-Shakra, F., Payne, R., Parry, T.C., Sinclair, P., Roberts, D. W. A comparison of the quantitative methods for the analysis of the platinum-containing anticancer drug cii-amminedichloro(2-methylpyridine)]-platinum(II) (ZD0473) by HPLC coupled to either a triple quadrupole mass spectrometer or an inductively coupled plasma mass spectrometer. Anal. Chem. 75, 1463-1469 (2003)... 

In the early 1980s quadrupole mass spectrometers using argon plasma as the ionization source, i.e., inductively coupled plasma mass spectrometers (ICP-MS), were developed. Although these instruments were designed primarily for measuring the concentrations of trace elements, many studies have employed them for U-Pb dating. and... 

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