PubMed identifier

Recently, in concert with MEDLINE and a large number of publishers, NCBI has introduced PubMed. PubMed contains all of MEDLINE, as well as citations provided directly by the publishers. As such, PubMed contains more recent articles than MEDLINE, as well as articles that may never appear in MEDLINE because of their subject matter. This development led NCBI to introduce a new article identifier, called a PubMed identifier (PMID). Articles appearing in MEDLINE will have both a PMID and an MUID. Articles appearing only in PubMed will have only a PMID. PMID serves the same pmpose as MUID in providing a simple, reliable link to the citation, a means of linking records together, and a means of setting up hyperlinks. 

Each GenBank record must have at least one reference or citation. It offers scientihc credit and sets a context explaining why this particular sequence was determined. In many cases, the record will have two or more reference blocks, as shown in Appendix 3.1. The preceding sample indicates a published paper. There is a MEDLINE and PubMed identifier present that provides a link to the MEDLINE/ PubMed databases (see Chapter 7). Other references may be annotated as unpublished (which could be submitted) or as placeholders for a publication, as shown. 

Figure 1 Domain map of the steroid receptor. The numbers correspond to residues of the human glucocorticoid a receptor at the boundaries of the regions identified in the schematic diagram. Source PubMed Primary accession number P04150.

C. S. Gibbs, D.R. Knighton, J.M. Sowadski, S.S. Taylor, and M.J. Zoller. 1992. Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit J. Biol. Chem. 267 4806-4814. (PubMed)... 

D M. Engelman, T.A. Steitz, and A. Goldman. 1986. Identifying non-polar transbilayer helices in amino acid sequences of membrane proteins Rev. Biophys. Biophys. Chem. 15 321-353. (PubMed)... 

B.N. Ames. 1979. Identifying environmental chemicals causing mutations and cancer Science 204 587-593. (PubMed)... 

P-Blocker and ACE inhibitor pharmacogenetic studies were identified in the PubMed database from 1966 to July 2013 by combining the following search terms heart failure, variant, polymorphism, pharmacogenetics, pharmacogenomics, p-blocker, ACE inhibitor, and each individual drug name. Studies were also identified from the reference lists of articles. Studies were limited to those performed in patients with HF and those published in English. 

MEDLINE and PubMed, both produced by the National Library of Medicine (NLM), are the largest and best known bibliographic databases of biomedical journal literature. PubMed s iu-process records provide basic citation information and abstracts before the citations are indexed with NLM s Medical Subject Headings (MeSH) Terms and added to MEDLINE. To optimize the efficiency of a clinical search, PubMed offers specialized searches usiug method-ologic filters. These filters, based on work by Haynes and colleagues, are validated search strategies to identify clinically relevant studies... 

The data are collected daily from a number of sources, including the National Center for Biotechnology Information (NCBI) and Gene Ontology (GO) Consortium. The warehouse includes sequences, structures, and complete genomes from Gen-Bank as well as annotation links such as NCBI taxon database terms, redundant sequences, sequence neighbors, conserved domains, Online Mendehan Inheritance in Man identifiers, GO terms, LocusLink identifiers, and PubMed links. 

PubChem is organized as three distinct databases PubChem Substance, PubChem Compound, and PubChem BioAssay. PubChem Substance contains descriptions of chemical samples, provided by dafa deposifors, and links to information on their biological activities. The description includes PubChem Compound identifiers in cases where the chemical structures of compounds in fhe sample are known. Links providing information on biological activity include those to PubMed [8] citations, protein 3-D structures [9], links to contributor websites, and to biological testing results available in PubChem BioAssay. 

Brown, R., et al., 2014. Continuous objeetive reeording of fetal heart rate and fetal movements eould reliably identify fetal eompromise, whieh eould reduee stillbirth rates by faeilitating timely management. Medieal Hypotheses 83 (3), 410—417. Available at http //www.nebi. nlm.nih.gov/pubmed/25109874 (aeeessed 05.09.14.). 

Literature search A Medline (Pubmed) search was conducted, using as search terms occupational exposure , NSAlDs , and the drug names of the agents covered in this chapter of SEDA (Table 1). The search was conducted in June 2012 without date restriction and with the limit human . The search identified case reports and case series of occupational contact dermatitis to propacetamol (a prodrug of paracetamol) and para-aminophenol (a breakdown... 

To serve as a basis for discussion on the design of recent TQT studies, a PubMed search was done (December 31) using the search terms thorough QT study 2012 and thorough QTc QT study 2012. Eighteen TQT studies published in 2012 were identified the key features of these studies and the response to the positive control, in all cases moxifloxacin, are summarized in Table 1. The limitations of this approach should be acknowledged The list is most likely not complete only a... 

Flin, R. and Maran, N. (2004), Identifying and training non-technical skills for teams in acute medicine. Quality and Safety in Health Care, 13, i80-i84. [PubMed 15465960] [DOI 10.1136/qshc.2004.009993]... 

The RLIMS-P [29] is a text-mining program that can be used to identify papers describing protein phosphorylation from all PubMed abstracts, and to extract from these abstracts the specific information on protein phosphorylation, namely the kinases, the protein substrates, and the amino acid residues/posifions being phos-phorylated (Fig. 5). The system achieved an overall recall of 96% for paper retrieval and a precision of 98% for extraction of substrates and phosphorylation sites. The RLIMS-P Web site [31] provides online retrieval of phosphorylation papers using PubMed ID, followed by extraction of phosphorylation information... 

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