Prostate cancer palliative therapy

Men taking estrogens generally do so in the course of palliative treatment for malignancies (prostatic carcinoma), for which high doses have sometimes been used. Estrogen therapy in men with prostate cancer may be superior to castration in terms of efficacy, but orally administered... 

International Agency for Research on Cancer has determined that radioactive strontium is a human carcinogen. Sr has been explored as an anticancer treatment, for example, for prostate cancer, and has been used as palliative treatment for patients with bone pain from osseous metastases. Excellent clinical responses for bone pain treatment have been observed (acceptable hematologic toxicity and clinical results rival those of external beam radiation therapy). 

Moderate to severe vasomotor mptoms associated with menopause, atrophic vaginitis, female hypogonadism, female castration, primary ovarian failure, palliative therapy for breast and prostate cancer, treatment of abnormal uterine bleeding due to hormone imbalance Moderate to severe vasomotor symptoms associated with menopause, atrophic vaginitis, female hypogonadism, female castration, primary ovarian failure Same as conjugated estrogens... 

Buserelin (Suprefact) and leuprolide (Lupron) are peptide analogues of the hypothalamic hormone LH-RH (luteinizing hormone-releasing hormone). Chronic exposure of the pituitary to these agents abolishes gonadotropin release and results in markedly decreased estrogen and testosterone production by the gonads. Their major clinical use is in the palliative hormonal therapy of cancer of the prostate. 

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