Propionic oxidation

Dehydrogenation of Propionates. Oxidative dehydrogenation of propionates to acrylates employing vapor-phase reactions at high temperatures (400—700°C) and short contact times is possible. Although selective catalysts for the oxidative dehydrogenation of isobutyric acid to methacrylic acid have been developed in recent years (see Methacrylic ACID AND DERIVATIVES) and a route to methacrylic acid from propylene to isobutyric acid is under pilot-plant development in Europe, this route to acrylates is not presentiy of commercial interest because of the combination of low selectivity, high raw material costs, and purification difficulties. 

Giiven D et al. (2005) Propionate oxidation by and methanol inhibition of anaerobic ammonium-oxidizing bacteria. Appl Environ Microbiol 71 1066-1071. 

Wallrabenstein C, E Hauschild, B Schink (1995) Syntrophobacter pfennigii sp. nov., new syntrophically propionate-oxidizing anaerobe growing in pure culture with propionate and sulfate. Arch Microbiol 164 346-352. 

Plugge CM, C Dijkema, AIM Stams (1993) Acetyl-CoA cleavage patyhways in a syntrophic propionate oxidizing bacterium growing on fumarate in the absence of methanogens. EEMS Microbiol Lett 110 71-76. 

Stams AIM, JB van Dijk, C Dijkema, CM Plugge (1993) Growth of syntrophic propionate-oxidizing bacteria with fumarate in the absence of methanogenic bacteria. Appl Environ Microbiol 59 1114-1119. 

The pathways and mechanism of interspecies transfer have been examined in syntrophic propionate-oxidizing organisms. 

Kosaka T et al. (2006) Reconstruction and regulation of the central catabolic pathway in the thermophilic propionate-oxidizing syntroph Pelotomaculum thermopropionicum. J Bacterial 188 202-210. 

Lueders T, B Pommerenke, MW Friedrich (2004) Stable-isotope probing of microorganisms thriving at thermodynamic limits syntrophic propionate oxidation in flooded soil. Appl Environ Microbiol 70 5778-5786. 

All known propionate oxidizers are also capable of reducing SO , and the biochemical components may include part of the S04 -reducing apparatus (Schink, 1997). Syntrophic propionate use occurs when SO is limiting and involves the transfer of H2 to a methanogenic... 

Harmsen H. J. M., Akkermans A. D. L., Stams A. J. M., and De Vos W. M. (1996a) Population dynamics of propionate-oxidizing bacteria under methanogenic and sulfidogenic conditions in anaerobic granular sludge. Appl. Environ. Microbiol. 62, 2163-2168. 

Textor, S., V.F. Wendich, A.A. De Graaf, U. Muller, M.I. Linder, D. Linder, and W. Buckel. 1997. Propionate oxidation in Escherichia coli evidence for operation of a methylcitrate cycle in bacteria. Arch. Microbiol. 168 428-436. 

Propionate - Oxidation of fatty acids containing an odd number of carbons ultimately yields a three carbon molecule, propionyl-CoA. Propionyl-CoA is converted to succinyl-CoA in an unusual set of reactions shown here. Succinyl-CoA can ultimately be converted to the gluconeogenic intermediate, oxaloacetate. 

Reda et al. reported a comprehensive electrochemical investigation of the catalytic voltammetry of the W-dependent FDH from the propionate oxidizing bacterium Syntrophobacter fumaroxidans (FDHl). This enzyme... 

Phenolic compounds Phosphorus Phosphorus bromides Phosphorus chlorides Phosphorus oxychloride Phosphorus oxides Piperazine Potassium Potassium cyanide Potassium difluoride Potassium hypochlorite Potassium permanganate Povidone iodine Propionic oxide Propylene oxide... 

Peuhkurinen KJ (1982)Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart. Biochem. Biophys. Acta 721 124-134 Randle PJ, Tubbs PK (1979) Carbohydrate and fatty acid metabolism. In Berne, RM, Spherelakis N, Geiger SR (eds) Handbook of Physiology, The Cardiovascular System. Bethesda pp 804-844... 

The potential of electrons transferred to ferricyanide in this system was estimated at -80 to -140 mV. Assuming that a minimum AEo of about 140 mV is needed to translocate one proton across the cytoplasmic membrane, the ATP yield by oxidative phosphorylation in the case of glycerol, lactate and propionate oxidation to acetate must be 1.0, 0.66 and 0.66, respectively. The yields of biomass observed experimentally were in accord with the calculated ATP yields. The authors also showed that the reduction of ferricyanide (Eo = +430 mV) occurs close to the potential of menaquinone (Emde and Schink, 1990a). 

Vagelos, P. R. and Earl, J. M. (1959) Propionic acid metabolism. HI. jS-Hydroxpropionyl coenzyme A and malonyl semialdehyde coenzyme A, intermediates in propionate oxidation by Clostridium kluy-veri. J. Biol. Chem. 234, 2272. 

Robertson, J. S, Hsia, Y. E, and Scully, K. J. (1976) Defective leukocyte metabolism in human cobalamin deficiency impaired propionate oxidation and serine biosynthesis reversible by cyanocobalamin therapy, J. Lab. Clin. Med., 87 89. 

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