Programming Environments

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Recursive techniques have been in use since the early days of digital computers. However, we have seen little use of this technique in formula calculations. Implementation requires the ability to calculate and return the same type of data for a formula as is normally retrieved from a raw material database. We have outlined some of the difficulties in using recursion. None of them present insurmountable difficulties if the programming environment being used supports recursion. The benefit of implementation is in the power of the software to simplify experimentation and formula development. 

Gilbertson M. 1997. Great Lakes forensic toxicology and the implications for research and regulatory programs. Environ Toxicol Chem 16 1771-1778. 

Hebert C, Nordstrom R, Weseloh DV. 1999. A quarter century of environmental surveillance the Canadian Wildhfe Service s Great Lakes Herring Gull Monitoring Program. Environ Rev 7 147-166. 

Klaessens [14-17] developed a laboratory simulator , written in SIMULA, which by a question-answering session assembles the simulation model. SIMULA [18] is a programming environment dedicated to the simulation of queuing systems. KEE [ 19] offers a graphics-driven discrete event simulator, in which the objects are represented by icons which can be connected into a logical network (e.g. a production line for the manufacturing of electronic devices). Although KEE has proven its potential in many areas, no examples are known of analytical laboratories simulated in KEE. 

Hopper K, McDonald TA (2000) The PBDEs an emerging environmental challenge and another reason for breast-milk monitoring programs. Environ Health Perspect 108 387... 

Metcalfe-Smith, J.L. 1994. Influence of species and sex on metal residues in freshwater mussels (Family Unionidae) from the St. Lawrence River, with implications for biomonitoring programs. Environ. Toxicol. Chem. 13 1433-1443. 

Holt83] Holt, A. W., H. R. Ramsey, and J. D. Grimes. 1983. Coordination system technology as the basis for a programming environment. Electrical Communication, 57(4). 

Klopman, G. (1985). Predicting toxicity through a computer automated structure evaluation program. Environ. Health Perspect. 61 269-274. 

Zeiger E, Haworth S, Speck W, et al. 1982. Phthalate ester testing in the National Toxicology Program s environmental mutagenesis test development program. Environ Health Perspect 45 99-101. 

Becker, R. A., Chambers, J. M., Wilks, A. R. The New S Language A Programming Environment for Data Analysis and Graphics. Chapman Hall, London, United Kingdom, 1988. 

Yoon JS, Mason JM, Valencia R, et al. 1985. Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ Mutagen 7 349- 367. 

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Finnish Ministry of Social Affairs and Health (1998) Finnish Occupational Exposure Limits 1998. Concentrations Known to be Harmful. [http //www.occuphealth.fi]oel eng.htm Foureman, R, Mason, J.M., Valencia, R. Zimmering, S. (1994) Chemical mutagenesis testing in Drosophila. X. Results of 70 coded chemicals tested for the National Toxicology Program. Environ, mol. Mutag., 23, 208-227... 

Knudsen S (2004). Guide to Analysis of DNA Microarray Data. 2nd ed. Wiley-Liss, Hoboken, N.J. Pennie W, Pettit SD, Lord PG. Toxicogenomics in risk assessment an overview of an HESl collaborative research program. Environ Health Perspect 2004 112 417 19. 

LaKind JS, Berlin CM, Naiman DQ (2001) Infant exposure to chemicals in breast milk in the United States what we need to learn from a breast monitoring program. Environ Health Perspect, 109(1) 75-88. 

Myhr BC, Caspary WJ. 1991. Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells Results for 31 coded compounds in the National Toxicology Program. Environ Mol Mutagen 18 51-83. 

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