Production line monitoring

In most spinning processes, the fiber emerging from the spinneret is drawn down to a desired dimension before complete solidification. In some production lines, a laser beam is uti1i2ed to monitor the dimensions of emerging thread any alteration is recorded and if required, the dope deHvery rate, take-up rate, and internal-injection medium deHvery rate are adjusted automaticaUy. 

Process monitoring, both in the laboratory and on the production line, is an important appHcation of infrared spectrometry (see Process control). 

Beverages. The quahty control for carbonated beverages encompasses all aspects of the product from actual chemical components to the physical condition of the container. The beverage is evaluated using laboratory tests as well as in-line monitors. 

The key phrase in this clause is or otherwise verified as it allows you to receive product into your company and straight onto the production line if you have verified that it conforms to the specified requirements before it arrives. An example of this is where you have performed acceptance tests or witnessed tests on the supplier s premises. You may also have obtained sufficient confidence in your supplier that you can operate a Just-in-time arrangement but you must be able to show that you have a continuous monitoring program which informs you of the supplier s performance. 

OS 91] [R 9] [P 71] By in-line spectrometry, the course of the reaction can be directly followed when changing the residence time (Figure 4.98). For decreasing reaction times, increasing flow rate, a decrease in absorption of the product was monitored, as expected [22]. 

A variety of optical systems have been described which use optical fibres to perform remote Raman spectroscopic analyses. These are of particular value when the sample has to be observed under hostile or hazardous environmental conditions, such as the in-line monitoring of chemical production. The collection radius of such fibre-optic probes is of the order 100 pm. 

Special optical fibres have been intensively investigated during recent years because of their potential wide-range use for on-line monitoring of material properties or processes in a number of areas of human activity (environment protection, food industry, medicine etc.) Their technology can be considered an integral part of the team-work on optical fibre sensors development. Despite special optical fibres represent a unique and often indispensable tool for a variety of sensor applications, special fibre production still represents only a small fraction of the market. Probably it is because of their low consumption (in comparison with standard telecommunication fibres), the need for much more advanced know-how and lower reproducibility. 

A. Gebbert, M. Alvarez-Icaza, H. Peters, V. Jager, U. Bilitewski, and R.D. Schmid, On-line monitoring of monoclonal antibody production with regenerable flow-injection immuno systems. J. Biotechnol. 32, 213-220 (1994). 

In chlorate production the EMOS system has also been used to determine the formation of deposits on the electrodes, either the anode or cathode and combined with the information on process and electrolyte composition the system determines the need for cell cleaning or acid rinsing. The close monitoring of individual cell voltages has allowed plant engineers to establish the most appropriate current density for production lines dependent upon the state of the anode coatings. This allows for the same overall production capacity while permitting the operation of two different cell lines in the cell room at different current densities based upon the state of the anodes and cathodes in the cell. 

The lead time, for incorporation of enzymes as an adjunct in whatever form into commercial food processes, appears to be far longer than equivalent innovation lead times m non-food, or even pharmaceutical processes. The exception to this finding is that there are enzymes which play an important role in many analytical and quality control procedures in the food industry, without the use of which, for batch or continuous process monitoring, many product lines would not be possible. 

Based on these chemosensors, biosensors can be set up such as glucose or H2O2 sensors. In this case the appropriate biological compound (glucose oxidase or catalase) must be immobilized on the chemosensor. Different optical sensors are also used as transducer elements for the production of biosensors, especially of immuno-sensors. Here the affinity component is immobilized on the tip of the fiber and all available immuno-sensing assays can be performed using this transducer element. Since these sensors cannot be sterilized and used for on-line monitoring in a bioprocess we refer to other publications [25-27]. 

An on-line monitoring of an industrial chromatographic process was realized by using the Bio View sensor. 2D-fluorescence spectroscopy allows automatic real time measurements directly at the outlet of the chromatographic columns. The fluorescence technique for separating different amino acids is faster and more accurate than conventional methods. The appHcation of the Bio View sensor will reduce costs and will increased the productivity of further chromatographic separations [92,93]. 

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