Sensitization polyvalent

Pirila V, Pirila L (1966) Sensitization to the neomycin group of antibiotics patterns of crosssensitivity as a function of polyvalent sensitization to different portions of the neomycin molecule. Acta Derm Venereol (Stockh) 46 489-496 Pirila V, Rouhunkoski S (1960) On cross-sensitization between neomycin, bacitracin, kana-mycin, and framycetin. Dermatologica 121 335-342 Pitmann FE, Pittman JC, Humphrey CD (1974) Lincomycin and pseudomembranous colitis. Lancet 1 451-452... 

It is neither convenient nor agreeable to experiment with man. Furthermore we cannot foresee what sensitization may lead to, even though the substance one uses may not often be found in everyday life (cross-sensitization , polyvalent sensitization etc.). On the other hand, this necessarily limits the number, time and quality of experiments. Nevertheless, the authors who have described experimental sensitizations in man give us interesting points of comparison. 

High refractory properties, extremely strong sensitivity to moisture and exceptionally high chemical activity of fluoride melts, especially of those containing ions of polyvalent metals, make spectral measurements of such melts extremely complicated. In order to obtain reliable results, the measurement cell must comply with three main requirements ... 

A similar type of biotin-dendritic multimer also was used to boost sensitivity in DNA microarray detection by 100-fold over that obtainable using traditional avidin-biotin reagent systems (Stears, 2000 Striebel et al., 2004). With this system, a polyvalent biotin dendrimer is able to bind many labeled avidin or streptavidin molecules, which may carry enzymes or fluorescent probes for assay detection. In addition, if the biotinylated dendrimer and the streptavidin detection agent is added at the same time, then at the site of a captured analyte, the biotin-dendrimer conjugates can form huge multi-dendrimer complexes wherein avidin or streptavidin detection reagents bridge between more than one dendrimer. Thus, the use of multivalent biotin-dendrimers can become universal enhancers of DNA hybridization assays or immunoassay procedures. 

Monophosphorylation pastes made from starch monophosphates also have greater clarity, viscosity and stability than unmodified starches,64 but are sensitive to salts, especially polyvalent cations.65 Variability in residual ash can lead to variability in the viscosity of monophosphorylated starches. Monophosphate substitution also lowers the gelatinization temperature at 0.07 DS, a value much greater than is found in food starches, the gelatinization temperature is below room temperature. Native potato starch contains 0.07 to 0.09% bound phosphorus and wheat starch contains 0.055% phosphoms, primarily as phosphoglycerides in the latter case. The FDA allows up to 0.4% phosphate as phosphoms.58 Monophosphates were used commercially in the US until about 1970. 

The solvent quality of water deteriorates by additions of alcohol and salt, singly and combined. Polyanions are especially sensitive to cations and are invariably precipitated by the di- and polyvalent species in sufficiently high concentration. Charge suppression by nonsolvents and cations decreases the polyanionic coil volume (vc) and simultaneously reverses the solute-solvent interaction through 0 to precipitation. Micromolecules can alter the dispersion rheology (Pastor et al., 1994) of charged an neutral polysaccharides. 

Carboxylic acid salts are more sensitive to low pH, polyvalent cations, and inert electrolyte in the aqueous phase than salts of organic phosphoric acids, and these in turn are more sensitive than organic sulfates or sulfonates. 

Nonquaternary cationics are generally sensitive to high pH, polyvalent anions, and inert electrolyte in the aqueous phase quaternary ammonium salts, on the other hand, are generally insensitive to these additives. 

Epidermin. [Henkel/Cospha] Polyvalent tissue complexes i o. for ag g and sensitive sl. ... 

Since the necessity for examining reaction sequences initiated by polyvalent recoiling atoms via their end products has been a severe experimental constraint, it may be worthwhile to repeat the prediction that high sensitivity laser absorption spectroscopy will in the near future permit direct detection of reactive intermediates in both chemical and recoil studies of atomic reactions. If this proves to be the case, then an exciting new era will have dawned in which recoil experiments may be able to answer many questions about the dynamics as well as the sys-tematics of polyvalent atomic reactions. 

Baer RL, Ramsay DN (1971) Polyvalent light sensitivity. Allergic contact sensitivity to sulisobenzone (letter). Arch Dermatol 104 446-448 Baer RL, Cohen HJ, Neidorff AH (1959) Allergic eczematous sensitivity to aminophylline. Arch Dermatol 79 647-648... 

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