Conjugated dendrimers

The opto-electronic properties of branched structures have been an area of some interest for a number of years, especially as NLO and light-emitting materials [82]. In particular, the use of u-conjugated dendrimers (mono-disperse macromolecules [83]) has flourished for a number of reasons ... 

M. Halim, I.D.W. Samuel, J.N.G. Pillow, A.P. Monkman, and P.L. Burn, Control of colour and charge injection in conjugated dendrimer/polypyridine bilayer LEDs, Synth. Met., 102 1571-1574,1999. 

Fluorescence anisotropy is generally used to provide information about the dipolar orientational dynamics occurring after excitation of a system. This technique has successfully been used to probe ultrafast dynamics of energy transfer in organic conjugated dendrimers. The detected emission intensities Tar and Ter for parallel and perpendicularly polarized excitation respectively, were used to construct an observable emission anisotropy R(t) in accordance with the equation [121] ... 

Weiner et al. (173) showed that the uptake of a folate-conjugate dendrimer into tumor cells overexpressing high affinity Folate Receptor (hFR), occurs through this type of endocytotic pathway. 

Peng ZH, Pan YC, Xu BB, Zhang J H (2000) J Am Chem Soc 122 6619-6623 Synthesis and optical properties of novel unsymmetrical conjugated dendrimers... 

Research Focus Development of conjugated dendrimers for use as electrically actuated... 

The convergent approach also permits the incorporation of functional repeat units. Because the repeat units comprise the majority of the dendritic structure, they represent an ideal location for multiple functional moieties. In addition to the numerous examples of conjugated dendrimers previously discussed 115.116.119-122.124-130,132-134,140-148,497 conver-... 

Fig. 8.2 Schematic structure of conjugated dendrimers. A conjugated core is surrounded by doubly branched conjugated dendrons, forming a second-generation dendrimer. The different conjugated groups are linked through linker units (L). The dendrimer is surrounded by surface groups (S), which control the interaction with the environment.

PAMAM dendrimer to target prostate-specific antigen (PSA) in prostate cancer. The antibody-conjugated dendrimer has been found to bind specifically to PSA positive cells (LNCaP human prostate cancer cell lines) but not with PSA negative cells (PC-3 human prostate cancer cell lines from bone) [50],... 

Figure 5.11 Structure of a conjugated dendrimers, star-shaped stilbenoid phthalocyanines [54]. (Reproduced with permission.)...

C. Kojima, T. Suehiro, K. Watanabe, M. Ogawa, A. Fukuhara, E. Nishisaka, A. Harada, K. Kono, T. Inui, and Y. Magata, Doxorubicin-conjugated dendrimer/collagen hybrid gels for metastasis-associated drug delivery systems, Acta Biomater., 9 (3), 5673-5680,2013. 

Thomas TP, Patri AK, Myc A, Myaing MT, Ye JY, Norris TB, Baker JR Jr (2004) In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules 5 2269-2274... 

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