Polylactide nanofibers

D., and Li, X. (2008) Novel nanocomposite of nano FojO and polylactide nanofibers for appUcation in drug uptake and induction of cell death of leukemia cancer cells. Langmuir, 24, 2151—2156. 

Fig. 6 Coalescence of soft nanofibers, a Directly during deposition of soft fibers in electrospinning of cellulose acetate, b Result of annealing of polylactide nanofibers at enhanced temperatures [89]...

Electrospinning of biodegradable polylactide/hydroxyapatite nanofibers study on the morphology, crystallinity structure and thermal stability. Polym. Degrad. Stab., 97, 2052-2059. 

In order to facilitate uniform dispersion of the inorganic nanoparticles in polymer nanofibers, a surfactant is sometimes used. The nontoxic and cell-friendly surfactant 12-hydroxystearic acid (HSA) was used to incorporate the hydrophilic ceramic powder hydroxyapatite (HA), which presents low affinity for organic solvents and hydrophobic polymers, into polylactide (PLA) [5]. The surfactant stabilizes the dispersion that otherwise would settle within a few minutes. Other surfactants typically used are the anionic AOT [6-8] or the nonionic Triton-X-100 [9]. 

Recently, considerable attention has been focused on the blends of biocompatible and biodegradable polymers in view of their potential environmental and biomedical applications. Song et al. [127] fabricated polylactide (PLA) nanofibers and the formation of nanocomposites with Ti02 via solution blending. The results... 

Madhumathi K, Sudheesh Kumar PT, Abhilash S, Sreeja V, Tamura H, Manzoor K, Narr SV, Jayakumar R (2010) Development of novel chitin/nanosilver composite scaffolds for wound dressing applications. J Mater Sci Mater Med 21 807-813 Maiti P, Yamada K, Okamoto M, Ueda K, Okamoto K (2002) New polylactide/layered silicate nanocomposites role of organoclays. Chem Mater 14 4654—4661 Matthews JA, Wnek GE, Simpson DG, Bowlin GL (2002) Electrospinning of collagen nanofibers. Biomacromolecules 3 232-238... 

It is well known that proliferation or differentiation of nerve or muscle tissue can be enhanced by electrical stimulation, which is in part attributed to the propagation of action potentials upon stimulation. To exploit these physiological events, composites of biodegradable polymers with electroconduc-tive materials have been investigated for effective transmission of electrical signals to the cells cultured on them. PLCL and polyaniline, one of the widely used electrically conductive materials, were mixed to fabricate the nanofiber meshes, illustrating that myotube formation was accelerated when the myoblasts were cultured on polyaniline-containing nanofibers compared to that of PLCL-only nanofibers, even without electrical stimulation (Jun et ah, 2009). Another electroconductive polymer, polypyrrole, was also used as a composite with other synthetic polymers. For example, polypyrrole was incorporated as particles into polylactide scaffolds, and the fibroblasts cultured on them with various intensities of DC current showed controlled proliferation in a current-dependent manner (Shi et al., 2004). 

Fig. 13 Porous nanofibers obtained via phase separation processes during electrospinning for mixtures of polylactide and polyethylene oxide [54]...

Fig. 16 Nonwoven composed of a Thick nanofibers and thin PA 6 nanofiber, b Thick polyamide 6 (PA 6), and thin polylactide fibers [38]...

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