Polyguanylic acid

Table I. Relative Yields of Diastereomeric Adducts From Anti-diol Epoxide Plus Polyguanylic Acid Compared to Adducts Generated During Metabolism of BP-7,8-dihydrodiol by Ram Seminal Vesicles in the Presence of Arachidonic Acid...

In either case, these electrophilic intermediates should be capable of reaction with nucleophilic cellular constituents. The interactions of NPy and a-acetoxyNPy with guanosine and polyguanylic acid are currently being investigated. 

Polydeoxyinosinic-deoxycytidylic acid sodium salt Polydeoxyadenylic-thymidylic acid sodium salt Polydeoxyguanylic-deoxycytidylic acid sodium salt Polydeoxyguanylic-polydeoxycytidylic acid sodium salt Polycytidylic-polyguanylic acid sodium salt Polyadenylic-polyuridylic acid sodium salt 8-Oxo-7,8-dihydroguanine Further oxidation products of 8-oxo-G... 

Lysine-rich proteinoids preferentially interact to form microparticles with polycytidylic acid and polyuridylic acid. On the other hand arginine-rich proteinoids interacts much more readily with polyguanylic acid and polyinosinic acid to form such particles under the same condition57>. Lysine-rich proteinoids had most often shown a preferential precipitation with polyuridylic acid in the experiments for interaction between polynucleotides and the proteinoids in the presence of Mg2+ 56). 

All other configurations were not hitherto observed except for GG22, which was proposed to occur in the quadruple helix formed by polyguanylic acid [po-ly(G)]4 [533]. The base quadruple is of the form depicted in Fig. 16.8. 

PMOXA-fc-PDMS-Z -PMOXA polymer vesicles have been functionalized with the oligonucleotide polyguanylic acid for specific recognition... 

Fig. 8. A view down the helix axis of four stranded polyguanylic acid. Polyinosinic acid has the same...

Abbreviations DNA deoxyribonucleic acid RNA ribonucleic acid rRNA ribosomal RNA tRNA transfer RNA. A adenine U uracil G guanine C cytosine, poly A polyadenylic acid poly U polyuridylic acid poly C polycytidylic acid poly I poly-inosinic acid poly G polyguanylic acid. The letters r and d refer to the ribose or deoxy-ribose series. Complexes between the polynucleotides are written as follows polyG poly C double-stranded helical complex of poly G and poly C 2 poly G poly C, triple-stranded complex. BSA bovine serum albumin MBSA methylated bovine serum albumin. N nitrogen. AMV Avian myeloblastosis virus NDV Newcastle disease virus. SLE systemic lupus erythematosus. 

PocHON, F., Michelson, A. M. Polynucleotides, VI. Interaction between polyguanylic acid and polycytidylic acid. Proc. nat. Acad. Sci. (Wash.) 53, 1425-1430 (1965). 

Poly-VCy can form a stable complex with polyguanylic add (poly G) and polyinosic acid (poly I) in water-propylene glycol solution. However, die structure of the complex appears to be irregular14. Poly-9-vinylhypoxanthine tends to produce the complex to a lesser extent as compared with the other vinyl polymers, probably due to its low solubility10. ... 

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