Poly unsaturated fatty acid PUFA

Poly-unsaturated fatty acids (PUFA), especially n-3 fatty acids, are well known for their health benefits [26], Fish oil as starting material for the separation of PUFA is a cheap source, but its fractionation is difficult. Separation techniques based on urea precipitation or silver ion chelate formation are less favored because of waste... 

Finally, another class of fatty acids that are valuable for their nutritional and health attributes aud less for their functional properties is the co-3 long-chain poly unsaturated fatty acids (PUFAs) which are mainly found in fatty fish. Today, researchers suggest that co-3s and co-6s at certain ratios are beneficial for consumers (infants, children, and adults) preventing implications for cardiovascular and brain diseases. 

It is largely accepted that a high dietary intake of poly-unsaturated fatty acids (PUFA) in the co-3 series has beneficial effects. Recently, cellular Hpid metabolism has been suggested as a target for cancer therapy. Cancer cells, compared with normal cells, seem to be vulnerable to exposure of certain polyunsaturated fatty adds (PUFAs), especially those in the to-3 series. Characteristic for these compounds are their poor ability to be oxidized in the cell due to multiple double bonds. They are however likely to be ester-ified to other lipids, and their incorporation into membrane phospholipids will influence membrane properties such as fluidity, protein interactions and susceptibility to lipid peroxidation. The hypolipidemic properties of some (o-3 fatty acids, such as EPA, are probably explained by an induction of mitochondrial 3 -oxidation that is not found after administration of the non-hypolipidemic (o-3 PUFA docosahexaenoic acid (DHA). However, both eicosapentaenoic acid (EPA) and DHA cause increased peroxisomal... 

Among nutritional interactions that may have an influence on the effect of vitamin E on immune responses and disease resistance, vitamin A and poly-unsaturated fatty acids (PUFA) are particularly interesting since they have, themselves, immunoregulatory roles (Mertin and Meade, 1977 Sheffy and Schultz, 1979), Protein malnutrition, and selenium effects are discussed elsewhere in this symposium, thus will not be mentioned here. 

SFA-Saturated fatty acids (capric acid, caprylic acid, myristic add, lauric acid, palmitic acid, stearic acid). Note MUFA, monounsaturated fatty acids PUFA, poly unsaturated fatty adds. 

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