Poly ester fatty acid incorporation

It is largely accepted that a high dietary intake of poly-unsaturated fatty acids (PUFA) in the co-3 series has beneficial effects. Recently, cellular Hpid metabolism has been suggested as a target for cancer therapy. Cancer cells, compared with normal cells, seem to be vulnerable to exposure of certain polyunsaturated fatty adds (PUFAs), especially those in the to-3 series. Characteristic for these compounds are their poor ability to be oxidized in the cell due to multiple double bonds. They are however likely to be ester-ified to other lipids, and their incorporation into membrane phospholipids will influence membrane properties such as fluidity, protein interactions and susceptibility to lipid peroxidation. The hypolipidemic properties of some (o-3 fatty acids, such as EPA, are probably explained by an induction of mitochondrial 3 -oxidation that is not found after administration of the non-hypolipidemic (o-3 PUFA docosahexaenoic acid (DHA). However, both eicosapentaenoic acid (EPA) and DHA cause increased peroxisomal... 

Ricinoleic acid is a bifunctional fatty acid containing a hydroxy group along the fatty chain. The presence of both carboxylic and hydroxyl groups allows incorporation of ricinoleic acid into a polymer backbone by formation of an ester bond. The synthesis of poly(ester-anhydride) contains two steps trans-... 

Air drying poly(ester amide) resins were produced by the incorporation of phthalic anhydride in poly(styrene-co-maleic anhydride)-based room temperature cured poly (ester amide). This was prepared by the condensation reaction between AA -bis(2-hydroxy ethyl) linseed oil fatty amide and a copolymer of styrene and maleic anhydride in the presence of an acid catalyst (Fig. 5.5). ... 

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