Point-of-care device

In addition to laboratory blood analyzers and portable point-of-care devices, which require blood collection, continuous monitoring of ion activities in a blood stream via implanted ion-selective electrodes is of great interest. The term biocompatibility refers to the ability of a sensor not to cause toxic or injurious effects while being in contact with living tissue. As dealing with any foreign object introduced into the human body, biocompatibility and hemocompatibility particularly are the most important requirements. 

The interest in manipulating cells in microfluidic devices is growing because of increasing interest in the development of devices that use ceUs for basic research and clinical diagnostic purposes [8], High throughput methods for manipulation of cells that could be applied to complex cell mixtures are expected to have a great impact in the development of point-of-care devices. 

In the other hand, as known, immunoassay has been developed for over 50 years, hence playing a particularly important role in the diagnosis of whole blood. When combining with the microfluidics, the on-chip whole blood immunoassay can promote the development of the POC (point-of-care) devices rapidly and offer many obvious benefits high specificity, high sensitivity, low sample volume and reagent consumption, rapidity, accuracy, and portability. 

Validation and regulation of point of care devices for medical applications... 

---