Picrasma javanica

Alkaloids are known in the family including -carbolines (barman) and canlhinone. Of 26 species tested, the following were previously known to be alkaloidal and also gave positive tests in this study Ailanthus altissima (2/4), A. excelsa, Alvaradoa amor-phoides (1/3), Picrasma javanica (1/4). 

Picrasma javanica is a medium-sized tree found in New Guinea, Southeast Asia and Indonesia. Decoctions of its bark are used in folk medicine as a febrifuge and as substitute for quinine [69],... 

Since then, seven more C25 quassinoids have been discovered Odyendane (215) and odyendene (216) from the Odyendea gabonensis [90], klaineanolide A (217) and B (218) from the Hannoa klaineana [61], indaquassin F (219) from the Quassia indica [80], javanicinoside E (220) isolated from the Picrasma javanica [76] and the new epimer from simarolide (221) [91],... 

Koike K, Yokoh M, Furukaw M, Ishil S, Ohmoto T (1995) Picrasane quassinoids from Picrasma javanica. Phytochemistry 40 233-238... 

Picrasma javanica Blume Antidote (poison), malaria (Bk), wound (L) [113]... 

C. erecta, Eurycoma longifolia, Picrasma javanica Blume, P. quassioides. Quassia africana, Q. amara, Q. gabonensis, Q. indica, Q. undulata, Simaba cedron, and Simarouba amara. 

Lastly, three Simaroubaceae species are described as antivenom Brucea antidysenterica. Quassia amara, and Simaba cedron, with a veiy strong convergence of use for the cotyledons of Simaba cedron seeds in South America). Brucea antidysenterica, Brucea javanica, Eurycoma longifolia. Quassia undulata, and Picrasma javanica are known as antidotes to food poisoning or other types poisoning. Central nervous system troubles, such as dementia, nervousness, and epilepsy, and alcohol addiction are treated with preparations of Ailanthus altissima. Quassia undulata, Simarouba amara, or Picrasma excelsa. 

Forty-five quassinoids isolated from the three Simaroubaceous plants, Brucea javanica, Brucea antidysenterica and Picrasma ailanthoides, and fourteen isolated from Ailanthus altissima were tested for Okano et al. [106-108] for their inhibitory activities using a short-term in vitro assay of the EBV-EA activation induced by TP A in Raji cells. 

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