Phyto-estrogens

Yeung J, Yu TF. Effects of isoflavones (soy phyto-estrogens) on serum lipids analysis of randomized controlled trials. Nutr. J. 2, 15, 2003. 

Adlercreutz H, Mazur W. 1997. Phyto-estrogens and western diseases. Ann Med 29 95-120. 

Kurzer MS and Xu X (1997) Dietary phyto estrogens. Annual Reviews of Nutrition 17, 353-81. 

Isoflavones are found in Glycine max (soybean). Clinical research has demonstrated soy isoflavones to be effective in menstrual diseases. They have antioxidant activity also. Isoflavones belong to a group of compounds known as phyto-estrogens. The isoflavone content of soybean is 10 tO 20 times more than other plants. Genistein is a potent tyrosine inhibitor, whereas daidezein has antioxidant activity. Recently isoflavones have been investigated for hypolipidemic activity. 

The sterols like compounds are sometimes refereed to as phyto-estrogens because of hormone like activity. Shatavarins present in Asparagus racemosus has significant anticholinergic activity. 

Metabolism of Lignans and their Phyto-Estrogenic Activity.613... 

METABOLISM OF LIGNANS AND THEIR PHYTO-ESTROGENIC ACTIVITY... 

Coumarins and furocoumarins - These compounds increase human and animal sensitivity to ultraviolet light and are used to treat vitiligo. Some have phyto-estrogenic action. When eaten by sheep and other animals, plants containing coumarins and furocoumarins have contraceptive action. Ingestion can cause fetal death in early pregnancy as well. 

Finlay, E.M.H., Wilson, D.W., Adlercreutz, H., and Griffiths, K., The identification and measurement of phyto-estrogens in human saliva, plasma, breast aspirate or cyst fluid, and prostatic fluid using gas chromatography-mass spectrometry, J. Endocrinol, 129 (Suppl) 49, 1991. 

Morton, M.S., Arisaka, O., Miyake, A., and Evans, B., Analysis of phyto-estrogens by gas-chromatography-mass spectrometry. Environ. Toxicol Pharmacol, 1, 221-225, 1999. 

Van Meeuwen JA, van den Berg M, Sanderson JT, Verhoef A, Piersma AH. 2007. Estrogenic effects of mixtures of phyto- and synthetic chemicals on uterine growth of prepubertal rats. Toxicol Lett 170 165-176. 

Estrogens 17-p Estradiol Coumestrol Medroxyprogesterone Phyto-P-SERM Progesterone... 

Mueller, S.O., Kling, M., Arifin, F.P., Mecky, A., Duranti, E., Shields-Botella, J., Delansome, R., Broschard, T., and Kramer, P.J., Activation of estrogen receptor alpha and ERbeta by 4-methylben-zylidene-camphor in human and rat cells comparison with phyto- and xenoestrogens, Toxicol. Lett, 142, 89-101, 2003. 

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