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Physiologically-based pharmacokinetic applications

Notice Approaches for the Application of Physiologically-Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment E-Docket ID No. ORD-2005-0022. Fed Reg July 28, 2005 70 (144) 43692-43693. [Pg.525]

LE Gerlowski, RK Jain. Physiologically based pharmacokinetic modeling Principles and applications. J Pharm Sci 72 1103-1127, 1983. [Pg.101]

Himmelstein, K. J., Lutz, R. J., A review of the applications of physiologically based pharmacokinetic modelling, J. Pharmacokinet. [Pg.154]

Andersen ME (1995) Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment. Toxicol Lett 79 35-44... [Pg.136]

Medinsky MA. 1995. The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling to understanding the mechanism of action of hazardous substances. Toxicol Lett 79 185-191. [Pg.218]

Levitt, D.G., PKQuest a general physiologically based pharmacokinetic model — introduction and application to propranolol, BMC Clin. Pharmacol, 1, 5, 2002. [Pg.372]

Leung HW. 1991. Development and utilization of physiologically based pharmacokinetic models for toxicological applications. J Toxicol Environ Health 32 247-267. [Pg.171]

Reddy, M.B., R.H. Yang, H.J. Clewell, and M.E. Andersen. 2005. Physiologically Based Pharmacokinetic Modeling Science and Applications. Hoboken, NJ John Wiley Sons. [Pg.51]

Reddy, M., Yang, R. S., Andersen, M Clewell, H. Physiologically Based Pharmacokinetic Modelling Science and Applications, 2006. [Pg.482]

Suzuki H, Iwatsubo T, Sugiyama Y. 1995. Applications and prospects for physiologically based pharmacokinetic (PB-PK) models involving pharmaceutical agents. Toxicol Lett 82/83 349-355. [Pg.263]

Yang RSH, Andersen ME. 2005. Physiologically based pharmacokinetic modeling of chemical mixtures. In Reddy MB, Yang RSH, Clewell HI HI, Andersen ME, editors, Physiologically based pharmacokinetics science and applications. New York lohn Wiley Sons, p 349-373. [Pg.268]

Yang RSH, Mayeno AN, Lyons M, Reisfeld B. 2010. The application of physiologically-based pharmacokinetics (PBPK), Bayesian population PBPK modeling, and biochemical reaction network (BRN) modeling to chemical mixture toxicology. In Mumtaz M, editor, Principles and practices of mixture toxicology. Hoboken (NJ) John Wiley Sons. [Pg.269]

Kim, C.S., Ross, I.A., Sberg, J.A., and Preston, E. 1998. Quantitative low-dose assessment of seafood toxin, domoic acid, in the rat brain application of physiologically-based pharmacokinetic (PBPK) modeling. Environ Toxicol Pharmacol 6, 49-58. [Pg.246]

Bruckner, J.V., Keys, D.A., Fisher, J.W. (2004). The acute exposure guideline (AEGL) program applications of physiologically based pharmacokinetic modeling. J. Toxicol. Environ. Health. Part A 67 621-34. [Pg.61]

H. J. Clewell, The Application of Physiologically Based Pharmacokinetic Modeling in Human Health Risk Assessment of Hazardous Substances, Toxicological Letters, 79(1-3), 207-217 (1995). [Pg.81]

Reddy MB, Y ang RSH, Clewell HJ, 3rd, Andersen ME. Physiologically based pharmacokinetics modeling Science and applications. Hoboken, NJ John Wiley Sons, 2005. [Pg.61]

USEPA. Approaches for the application of physiologically based pharmacokinetic (PBPK) models and supporting data in risk assessment. Report number EPA/600/ R-05/043A. Washington, DC US Environmental Protection Agency, 2005. [Pg.62]

Lupfert, C. and Reichel, A. (2005) Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery. Chemistry e[ Biodiversity, 2 (11), 1462-1486. [Pg.485]

Hamon J, Perez Schonberg T, Bois FY (in press) Physiologically-based pharmacokinetic modeling. In Ruiz-Garcia A, Casabo VG (eds) Pharmacokinetics concepts and applications in drug discovery and development. Wiley, Hoboken, NJ... [Pg.547]

M. V. Evans, W. D. Crank, H. M. Yang, and J. E. Simmons, Applications of sensitivity analysis to a physiologically based pharmacokinetic model for carbon tetrachloride in rats. Toxicol Appl Pharmacol 128 36-44 (1994). [Pg.1093]


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See also in sourсe #XX -- [ Pg.791 ]




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