Phenylephrin

The analysis of a pharmaceutical preparation for pheniramine maleate and phenylephrine hydrochloride is described in this experiment. 

Phenylephrine (90) is a selective receptor agonist (+)-niguldipine (91) is a selective antagonist for the receptor. Pra2osin (92) and 5-methylurapidil (93) are nonselective a -receptor antagonists. CEC can differentiate receptors from the other receptors. Pra2osin has low and high affinity for and receptors, respectively. 

Phenylephrine. Phenylephrine hydrochloride is an a -adrenoceptor agonist. Phenylephrine produces powerful vasoconstrictor and hypertensive responses. This results in baroreceptor activation of a reflex bradycardia and thus is useful in the treatment of supraventricular tachyarrhythmias. Unlike epinephrine [51-43-4] the actions of which are relatively transient, phenylephrine responses are more sustained (20 min after iv dosing and 50 min after subcutaneous dosing) (86). 

Lion of action. The largest use of this drug, however, depends on its vasoconstricting action phenylephrine is used extensively as a nasal decongestant due to its ability to constrict the blood vessels in mucous tissue on local application. In one published... 

Levonordefrine Mephentermine Metaramino1 Methamphetamine A-Norepinephrine Phenylephrine... 

Exsel -Selenium sulfide Extencilline - Penicillin G benzathine Extendryl - Phenylephrine HCI Extracort - Triamcinolone acetonide Extramycin -Sisomicin Extranase - Bromelain Extren - Aspirin... 

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