Selenium sulfide

Medicated Dandruff Shampoos. Dandmff is a scalp condition characterized by the production of excessive cellular material (18). A number of shampoos have been marketed which are designed to control and alleviate this condition, and many additives have been included in shampoo compositions to classify them as treatment products for dandmff. These additives include antimicrobial additives, eg, quaternary ammonium salts keratolytic agents, eg, saUcychc acid and sulfur heavy metals, eg, cadmium sulfide coal tar resorcinol and many others. More recent (ca 1993) systems use selenium sulfide [7488-56-4] or zinc pyrithione [13463-41 -7] as active antidandmff shampoo additives. Both of these additives are classified as dmgs, but can be found in over-the-counter products. A stronger version, incorporating the use of higher levels of selenium sulfide in a shampoo, is available but requires a prescription for purchase. 

Also reported as commercial products are selenium amino acid chelate, selenium ascorbate, selenium aspartate, and selenium citrate triturations, as well as selenium dibromide, selenium dichloride, selenium lysinate, and selenium sulfide bentonite. 

Medicine and Nutrition. A stabilized buffered suspension of selenium sulfide has been marketed for many years as Selsun Blue (Abbott Laboratories) for control of seborrheic dermatitis of the scalp. A similar sulfur or selenium sulfide shampoo containing a metallic cation complex has been prepared (122). Topical appHcation of selenium sulfide controls dermatitis, pmritis, and mange iu dogs (see Cosmetics Veterinarydrugs). 

Seiko Chemical Co., Ltd, 188 Selenium and Selenium Compounds, 115 Selenium dioxide, 116 Selenium hexafluoride, 116 Selenium oxychloride, 116 Selenium sulfides, 116... 

Therapeutic Function Dermatological Chemical Name Selenium sulfides Common Name —... 

Exsel -Selenium sulfide Extencilline - Penicillin G benzathine Extendryl - Phenylephrine HCI Extracort - Triamcinolone acetonide Extramycin -Sisomicin Extranase - Bromelain Extren - Aspirin... 

Scalp involvement can be treated with twice-daily topical corticosteroids in conjunction with a shampoo containing selenium sulfide, coal tar, or salicylic acid to help soften and remove scales. 

Selenium photovoltaic cell, 22 100, 103 Selenium pink glass, 22 97 Selenium rectifiers, 22 99-100 Selenium ruby glass, 22 96-97 Selenium sulfide... 

Selenium sulfide (SeS ) is used for some medicines, as an additive for medicated shampoos to control dandruff and scalp itching, and in treatment products for acne and eczema. 

Uses. Semiconductors thermoelectric cooling power generation application for commercial use, Bi2Te3 is doped with selenium sulfide to alter its conductivity. 

Toxicology. Bismuth telluride, either alone or doped with selenium sulfide, is apparently of very low toxicity. 

Compounds Selenium dioxide selenium trioxide selenium oxychloride sodium selenite sodium selenate hydrogen selenide selenic acid selenium sulfide selenium disulfide... 

Epidemiological studies in humans do not suggest an association between excess exposure to selenium and cancer." Low levels of intake, however, have been associated with an increased risk of developing many kinds of cancers. With the exception of selenium sulfide, most animal studies have shown that selenium compounds inhibit tumorigenesis." High doses of selenium sulfide administered by gavage caused liver tumors in rats and lung... 

National Cancer Institute Bioassay of Selenium Sulfide (Gavage) for Possible Carcinogenicity, DHHS (NIH) Pub No 80-1750, 130pp. Washington, DC, US Governmental Printing Office, 1980... 

Kimmerle G Comparative research on the inhalation toxicity of selenium sulfide and tellurium hexafluoride. Arch Toxicol 18 140-144, 1960... 

In summary, it should be pointed out, however, that the exact mechanism of the thermal rearrangement of sulfur rings and chains is still unknown and that further investigations are necessary in this connection. For any further discussion it may also be interesting to take into account the recent results on the molecular rearrangement reactions of cyclic selenium sulfides and of elemental selenium which take place at considerably lower temperatures compared with elemental sulfur and for which — as far as solid selenium is concerned — interesting ionic mechanisms have been proposed... 

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