Phenyl carboxylic acid

Benzenecarboxylic acid carboxybenzene phenyl carboxylic acid phenylformic acid... 

Cocrystal systems are assembled through the association of individual molecules into fundamental building block units that are known as supramolecular synthons [13]. For example, one such synthon would be formed by hydrogen-bond interactions between a phenyl-carboxylic acid and a phenyl-amide, with the molecules being linked into a dimeric species through 0 H-N and O-H O hydrogen bonds [14], This mode of interaction can be illustrated using the synthon that would result from the dimerization of benzoic acid and benzamide ... 

KYSELINA BENZOOVA (CZECH) PHENYL CARBOXYLIC ACID PHENYLFORMIC ACID RETARDER BA RETARDEX SALVO LIQUID SALVO POWDER TENN-PLAS... 

Figure 2 Hammett dependence for the dissociation of substituted phenyl carboxylic acids.

PHENYL CARBOXYLIC ACID (65-85-0) C7HJO2 Combustible solid.Dust may form explosive mixture with air (flash point 250°F/121°C autoignition temp 1063°F/573°C Fire Rating 1). Incompatible with strong oxidizers, caustics, ammonia, amines, isocyanates. The aqueous solution is a weak acid. On small fires, use dry chemical powder (such as Piuple-K-Powder), foam, water spray, or COj extinguishers. PHENYL CELLOSOLVE [Union Carbide] (122-99-6) see ethylene glycol phenyl ether. 

PHENYL CARBOXYLIC ACID (65-85-0) Combustible (flash point 249°F/121°C). Dust can form explosive mixture with air. Incompatible with strong oxidizers, caustics, ammonia, amines, isocyanates. 

Benzoic acid (benzene-methanoic acid, benzene-formic acid, benzene-carboxylic acid, phenyl-carboxylic acid, carboxy-benzene) [65-85-0]... 

CARBOXYBENZENE DRACYLIC ACID PHENYL CARBOXYLIC ACID PHENYLFORMIC ACID RETARDEX SALVO... 

Eurthermore, in alkenylation reactions with phenyl carboxylic acid as the substrate, a similar annulation reaction proceeds to give a lactone by cyclization reaction via the alkenylation of the cyclometalation product, as shown in Eq. (7.80) [156],... 

Synonyms benzenecarboxylic acid carboxybenzene dracylic acid benzene formic acid benzenemethonic acid phenyl carboxylic acid phenylformic acid retarded BA Retardex Salvo Tennplas... 

Several hydroxylated and methoxylated derivatives of benzoic acid (phenyl carboxylic acid) occur in nature (Table 52). They are the mother substances of reduced compounds (derivatives of benzaldehyde and benzylalcohol), of de-carboxylated products (hydroquinone-derived compounds), but also of more complex substances, e.g., the gallotannins and ellagitannins. 

Acidum benzoicum Benzenecarboxylic acid Benzene formic acid Carboxybenzene Phenylformic acid Dracylic acid Phenyl carboxylic acid Purox B E 210. 

Amides from Carboxylic Acids. Al-Methoxy-iV-methyl amides can be prepared from carboxylic acids and the amine hydrochlorides. In the case of an a-phenyl carboxylic acid (eq 10), the amide is formed in 71% yield and no racemization is detected. ... 

As an example, the empirical formula of phenylalanine may be split into a more extended form that shows the presence of a phenyl ring, as well as an amino and a carboxylic acid group (the condensed form in Figure 2-4). 

Phenylglycine-o-carboxylic acid. In a 750 ml. round-bottomed flask, fitted with a reflux condenser, place 14 g. of anthranilic acid (Section IV,170), 10 g. of chloroacetic acid, 20 g. of anhydrous sodium carbonate and 200 ml. of water. Reflux the mixture for. 3 hours, then pour into a beaker, cool, render shghtly acid with concentrated hy dro-chloric acid, and allow to stand overnight. Filter off the crude acid and wash it with water. Recrystalhse from hot water with the aid of a little decolourising carbon, and dry the acid at 100°. The yield of phenyl-glycine-o-carboxyhc acid, m.p. 208°, is 12 g. 

The synthesis of 9H-benzo[2,l-e]thiazolo-[2,3-c]-as-triazine (401) was achieved by oxydative cyclization of 2-imino-3-(o-aminophenyl)-4-phenyl-4-thiazoline (718, 719). This latter reacts also with paraformaldehyde in hot toluene yielding 3-phenyl-9H.10H-benzo[l,2-/]thiazolo-[2,3-d][l,3,5]triazepine (402) (720). This heterocyclic sytem is also formed when carboxylic acids replace paraformaldehyde (Scheme 230) (721). 

Reaction of carboxylate ion with nitrophenyl sulfites gives the carboxylate -nitrophenyl esters. If the -nitrophenyl sulfite is unsymmethcal (02NCgH40S(0)0R, where R is ethyl or phenyl), carboxylate attacks the -nitrophenyl side (69). Some amino acids react with methyl and benzyl sulfites in the presence of -toluenesulfonic acid to give methyl and benzyl esters of the amino acids as -toluenesulfonate salts (70). With alcohols, the conversion of henzil to a monoacetal upon addition of sulfuric acid to the henzil in methanol and dimethyl sulfite proceeds in high yield (71). 

Some 4,5-disubstituted pyridazines exhibit ring-chain isomerism involving heterospiro compounds. For example, 5-(o-aminophenylcarbamoyl)pyridazine-4-carboxylic acid exists in a zwitterionic form in the solid state, but in a solution of DMSO it is almost exclusively 3, 4 -dihydro-3 -oxospiro[pyridazine-5(2//),2 (l //)-quinoxaline]-4-carboxylic acid (134). The equilibrium is strongly influenced by the nature of the solvent, the substituents on the pyridazine ring and the nucleophilicity of the group attached to the phenyl ring (Scheme 48) <80JCS(P2)1339). 

C3S2 s s — — — l,2-Dithiolane-4-carboxylic acid 3-phenyl-l,2-dithiolylium iodide 4-methyl-1,2-dithiole-3-thione ... 

When compound (443), which contains alkene and alkyne moieties, was reacted with benzonitrile oxide, both an isoxazoline (444) and isoxazole (445) were produced, with the former predominating. Oxidation of (444) with permanganate produced 3-phenyl-2-isoxazoline-5-carboxylic acid (446) (67ZOR82i). The reaction of 1-trimethylsilylbut-l-yne-3-ene produced only a compound which reacted at the alkenic unit. Oxidation of the adduct also produced (446) (68ZOB1820). These reactions are shown in Scheme 102. 

Both 1,2- and 2,1-benzisothiazoles react with electrophiles to give 5- and 7-substituted products (see Section 4.02.3.2). The isothiazole ring has little effect on the normal characteristics of the benzene ring. C-Linked substituents react almost wholly normally, the isothiazole ring having little effect except that phenyl substituents are deactivated (see Section 4.17.2.1). There are, however, considerable differences in the ease of decarboxylation of the carboxylic acids, the 4-isomer being the most stable (see Section 4.02.3.3). 

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