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Phenethyl isothiocyanate

MUSK s R, SMITH T K and JOHNSON I T (1995) On the cytotoxicity and genotoxicity of allyl and phenethyl isothiocyanates and their parent glucosinolates sinigrin and gluconasturtiin , Mutat Res, 348 19-23. [Pg.59]

GUO Z, SMITH T J, WANG E, SADRIEH N, MA Q, THOMAS P E and YANG C S (1992) Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabohzing enzymes and nitrosamine metabolism in rats . Carcinogenesis, 13 2205-10. [Pg.61]

CHUNG F L, CONAWAY c c, RAO c V and REDDY B s (2000) Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate . Carcinogenesis, 21 2287-91. [Pg.63]

Khor TO, Keum YS, Lin W, Kim JH, Hu R, Shen G, Xu C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN. 2006. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Res 66 613-621. [Pg.391]

Nakajima M, Yoshida R, Shimada N, et al. Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate. Drug Metab Dispos 2001 29(8) 1110-1113. [Pg.541]

Inhibition of the PKC isozyme superfamily elicits apoptosis in tumor cells. Phenethyl isothiocyanate (PEITC) conjugates of sphingosine and sphinganine (Fig. 13) exert potent antineoplas-tic effects in human leukemia HL-60 cells by the inhibition of conventional PKC/novel PKC activity and ERK1/ERK2 activity... [Pg.1773]

Lindros. K.O. et at. (1995) Phenethyl isothiocyanate, a new dietary liver aldehyde dehydrogenase inhibitor. J. Pharmacol. Exp. Then. 275.79-83. [Pg.10]

Staretz ME, Foiles PG, Miglietta LM, Hecht SS. 1997. Evidence for an important role of DNA pyridyloxobuty-lation in rat lung carcinogenesis by 4-(methylnitrosamino)-1 -(3-pyridyl)-l-butanone effects of dose and phenethyl isothiocyanate. Cancer Res. 57 259-66... [Pg.516]

Isothiocyanates Phenethyl isothiocyanate, benzyl isothiocyanate, sulforaphane Cruciferous vegetables (including brussel sprouts, kale, cabbage, broccoli, cauliflower, spinach, watercress, turnip, radish) Pungent flavor... [Pg.30]

In further work. Dr. Wattenberg found that phenethyl isothiocyanate and benzyl isothiocyanate added to the feed of mice inhibited chemically induced intestinal and mammary cancers. The cruciferous vegetables cabbage, brussels sprouts, cauliflower, kale, and turnips (of the mustard family, or family Cruciferae, or family Brassi-caceae) contain phenethyl isothiocyanate. Watercress, another example, contains benzyl isothiocyanate. [Pg.256]

Other noteworthy sulfur-containing mechanism-based inactivators include thiocyanates such as phenethyl isothiocyanate benzylisothio-cyanate , tert-butylisothiocyanatediallyl sulfide, and diallylsulfone derivatives 1,2-dithiole-3-thione , oltipraz, and its deriva-tives , sulforaphane " , and thiosteroids. ... [Pg.254]

Ishizaki, H., J.F. Brady, S.M. Ning, and C.S. Yang (1990). Effect of phenethyl isothiocyanate on microsomal N-nitrosodimetltylamine metabolism and other monooxygenase activities. Xenobiotica 20,255-264. [Pg.655]

In 1992 Chung et al. (793a) demonstrated that components, e.g., phenethyl isothiocyanate, indole-3-carbinol, in green tea and cruciferous vegetables inhibited lung tumorigenesis induced by NNK. [Pg.704]

Knasmuller S, Friesen MD, Holme JA, Alexander J, Sanyal R, Kassie F, Bartsch H. Effects of phenethyl isothiocyanate on metabolism and on genotoxicity of dimethylnitrosamine and 2-amino-l-methyl-6-phenylimidazo[4,5b]pyridine (PhlP). Mutat Res 1996 350 93-102. [Pg.143]

Kassie F, Laky B, Gminski R, Mersch-Sundermann V, Scharf G, Lhoste E, KansmuUer S. Effects of garden and watercress juices and their constituents, benzyl and phenethyl isothiocyanates, towards benzo(a)pyrene-induced DNA damage a model study with the single cell gel electrophoresis/Hep G2 assay. Chem Biol Interact 2003 142 285-296. [Pg.143]

Huang C, Ma WY, Ei J, Hecht SS, Dong Z. Essential role of p53 in phenethyl isothiocyanate-induced apoptosis. Cancer Res 1998 58 4102-4106. [Pg.250]

See other pages where Phenethyl isothiocyanate is mentioned: [Pg.679]    [Pg.1369]    [Pg.232]    [Pg.1369]    [Pg.136]    [Pg.30]    [Pg.679]    [Pg.256]    [Pg.574]    [Pg.679]    [Pg.9]    [Pg.19]    [Pg.493]    [Pg.162]    [Pg.264]    [Pg.66]    [Pg.82]    [Pg.67]    [Pg.679]    [Pg.301]    [Pg.128]    [Pg.630]    [Pg.18]    [Pg.659]    [Pg.746]   
See also in sourсe #XX -- [ Pg.1371 ]

See also in sourсe #XX -- [ Pg.1371 ]

See also in sourсe #XX -- [ Pg.82 ]

See also in sourсe #XX -- [ Pg.659 ]

See also in sourсe #XX -- [ Pg.40 , Pg.44 ]



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