Petrolatum mineral oil

Mometasone furoate Elocon White petrolatum, mineral oil... 

Gentamicin sulfate Prednisolone acetate Pred-G White petrolatum mineral oil petrolatum... 

Morrison, D.S., The effects of petrolatum, mineral oil and other hydrocarbons on the stratum corneum, Cosmet. Dermatol., November (Suppl.), 26, 1997. 

Nonmedicated ointments are indicated for moderate to severe dry eye, especially with lagophthalmos, persistent inferior corneal stippling, or severe epithelial compromise. Esters of latty acids with long-chain alcohols, such as petrolatum, mineral oil, lanolin, and lanolin alcohols, serve as lubricants and create a lipid layer, retarding evaporation. Although these preparations (Table 14-2) melt at the temperature of the ocular tissue and disperse with the tear fluid, they appear to be retained longer than other ophthalmic vehicles. Because of their molecular... 

Ointments, ophthalmic. Sterile ointments designed for application to the eyelids. Petrolatum, petrolatum-mineral oil, and petrolatum-anhydrous lanolin bases are often used in ophthalmic ointments because of their low irritating potential. Finely powdered, sterile active ingredients are aseptically incorporated into a sterile base, using sterile utensils, and dispensed in sterile ophthalmic-tipped tubes to reduce the possibility of contamination. ... 

Petrolatum-mineral oil ointment is retained longer on the eye than other vehicles. The large molecules of the petrolatum-mineral oil-base ointment are not easily removed by blinking, and a component of the comeal tear film is a non-polar oil. Ointments are oil bases and non-polar, which is why they are readily absorbed by the pre-corneal and conjunctival tear films. To maintain dmg contact with the eye, patching is recommended (1). 

Lijinsky W, Domsky I, Mason G, et al. 1963. The chromatographic determination of trace amounts of polynuclear hydrocarbons in petrolatum, mineral oil, and coal-tar. Anal Chem 35 952-956. 

The lubricating ointments are composed of a mixture of white petrolatum, mineral oil, liquid or alcohol lanolin, and sometimes a preservative. These highly viscous formulations cause considerable blurring of vision, and consequently they are used primarily at bedtime, in critically ill patients, or in very severe dry-eye conditions. Such aqueous and ointment formulations are only fair substitutes for the precorneal tear film, which is truly a poorly understood lipid, aqueous, and mucin trilaminar barrier. 

Synonyms Heavy mineral oil Light mineral oil Liquid paraffin Liquid petrolatum Mineral oil, white... 

Formulating Considerations Can be emulsified with anionic, cationic, or nonionic emulsifiers, soluble hot in fatty acids, fatty alcohols, fatty esters, petrolatum, mineral oil. Forms a flocculated dispersion upon cooling. Stable gels or dispersions form at 6-15%... 

Chem. Descrip. Lanolin, lanolin alcohol, petrolatum, mineral oil, paraffin, and cetearyl alcohol Ionic Nature Nonlonic... 

Synonyms Heavy mineral oil Light mineral oil Liquid paraffin Liquid petrolatum Mineral oil, white Oil mist, mineral Paraffin oil Paraffinum liquidum Petrolatum liquid Petroleum oil White mineral oil White oil Definition Liq. mixture of hydrocarbons obtained from petroleum by intensive treatment with sulfuric acid and oleum, or by hydrogenation, or a combination consists of predominantly C15-50 sat. hydrocarbons Properties Colorless transparent oily liq., odorless, tasteless insol. in water, alcohol sol, in benzene, chloroform, ether, petrol, ether, carbon disulfide, volatile oils dens, 0,83-0,86 (light), 0.875-0.905 (heavy) flash pt. (OC) 444 F surf tens. < 35 dynes/cm... 

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