Perfumers

Its chief importance is as a source of cinnamic acid by condensation with sodium ethan-oate and ethanoic anhydride and as a source of triphenylmethane dyestuffs by condensation with pyrogallol, dimethylaniline, etc. It is also used in the manufacture of perfumes. 

CH3 CH0H CH20H, a colourless, almost odourless liquid. It has a sweet taste, but is more acrid than ethylene glycol b.p. 187. Manufactured by heating propylene chlorohydrin with a solution of NaHCO under pressure. It closely resembles dihydroxyethane in its properties, but is less toxic. Forms mono-and di-esters and ethers. Used as an anti-freeze and in the preparation of perfumes and flavouring extracts, as a solvent and in... 

CifiHjoO. A yellow liquid b.p. 330°C. The perfume base obtained from the scent glands of the Tibetan musk deer also available by synthesis. 

C10H13O. B.p. 225-226"C. A terpenic alcohol and a constituent of neroli, petit-grain and bergamot, and of many other essential oils. Nerol has a blander smell than its isomer, geraniol, and is more valuable as a constituent of perfumes. 

SNG Substitute natural gas. soaps Sodium and potassium salts of fatty acids, particularly stearic, palmitic and oleic acids. Animal and vegetable oils and fats, from which soaps are prepared, consist essentially of the glyceryl esters of these acids. In soap manufacture the oil or fat is heated with dilute NaOH (less frequently KOH) solution in large vats. When hydrolysis is complete the soap is salted out , or precipitated from solution by addition of NaCl. The soap is then treated, as required, with perfumes, etc. and made into tablets. 

CaH803. Fine white needles, m.p. 82°C, b.p. 285°C, strong vanilla odour, characteristic taste. It occurs extensively in nature, and is the odoriferous principle of the vanilla pod it can be obtained from the glucoside coniferin. Vanillin is made commercially from the ligno-sulphonic acid obtained as a by-product in the manufacture of wood pulp. It is one of the most important flavouring and perfuming... 

Spirit G (petroleum ether) 0.645 30-75 (approx.) Petroleum gas equipment, perfume extraction... 

We made this important intermediate (A) in a slightly different way (frame 318), but this is how it s made industrially for use in perfumes and flavours (Pure. Annl. Chem.. 1975, 43, 527). How would you extend this synthesis to make TM 324 ... 

Revision Problem 4 Musks are compounds which have some pleasant smell themselves, but function chiefly by retaining and enhancing the perfume of other compounds. How might celestoHde , a modem musk, (TM 398) be made ... 

Cis-Jasmone (TM 422) is an important ingredient inmany perfumes. There are several obvious disconnections and it may help you to know that cychsation of the diketone 422A does indeed selectively give cis-jasmone. 

The lonones are fragrant substances present in the scent of ms and are used in perfume A mixture of a and 3 lonone can be prepared by treatment of pseudoionone with sulfuric acid... 

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