Ethanoic Anhydride

White crystals, m.p. 114" C. Manufactured by reacting aniline with excess ethanoic acid or ethanoic anhydride. Chief use is in the manufacture of dye intermediates such as p-nitro-acetanilide, p-nitroaniline and p-phenylene-diamine, in the manufacture of rubber, and as a peroxide stabilizer. 

Its chief importance is as a source of cinnamic acid by condensation with sodium ethan-oate and ethanoic anhydride and as a source of triphenylmethane dyestuffs by condensation with pyrogallol, dimethylaniline, etc. It is also used in the manufacture of perfumes. 

Prepared by healing benzaldehyde with sodium ethanoate and ethanoic anhydride (Perkin reaction) or with ethyl ethanoate and sodium ethoxide. Occurs in storax, or liquid... 

Lead(fl) ethanoate, Pb(02CCH3)2,3H20, sugar of lead. Soluble in water (ethanoic acid and ethanoic anhydride plus Pb304). 

Perkin reaction A condensation between aromatic aldehydes and the sodium salts of fatty acids or their aromatic derivatives. The reaction between benzaldehyde and sodium ethanoate in the presence of ethanoic anhydride leads to sodium cinnamate... 

Prepared by stirring phthalimide with cold concentrated ammonia solution. Hydrolysed to phlhalic acid with dilute acids. Dehydration with ethanoic anhydride gives first n-cyano-benzamide and then phthalonitrile. 

Acid anhydride RCOCR CH3COCCH3 Ethanoic anhydride... 

Chemical Designations - Synonyms Ethanoic Anhydride Chemical Eormula CH3CO-O-COCH3. Observable Characteristics - Physical State (as ruirmally shipped) Liquid Color. Colorless Odor Very strong pungent vinegar-like characteristic odor. 

Discussion. Hydroxyl groups present in carbohydrates can be readily acetylated by acetic (ethanoic) anhydride in ethyl acetate containing some perchloric acid. This reaction can be used as a basis for determining the number of hydroxyl groups in the carbohydrate molecule by carrying out the reaction with excess acetic anhydride followed by titration of the excess using sodium hydroxide in methyl cellosolve. 

Ethanedial, g28 1,2-Ethanediol, el 35 Ethanediamide, o58 Ethanenitrile, a29 Ethanoic acid, al9 Ethanoic anhydride, a22 Ethanolamine, a 164... 

Anhydrides Carbon, hydrogen, single bonds, and at least one -COOOC-in the molecule (may include double and triple bonds and other structures) HO OH 1 II II 1 H—C—C—0—C-C—H 1 1 H H Ethanoic anhydride... 

Synonyms Acetanhydride Acetyl acetate Acetic acid anhydride Acetic oxide Acetyl anhydride Acetyl ether Acetyl oxide BRN 0385737 Caswell No. 003A CCRIS 688 EINECS 203-564-8 EPA pesticide chemical code 044007 Ethanoic anhydrate Ethanoic anhydride UN 1715. 

Take aspirin, for example. It has its origins in salicin, the active ingredient in willow bark. When salicin is hydrolysed it produces glucose and salicyl alcohol the latter can be oxidised to salicylic acid. Salicylic acid was also used as a medicine, but it caused irritation and bleeding in the stomach and intestines. However, when salicylic acid is treated with ethanoic anhydride, acetylsalicylic acid (aspirin) is produced. 

In a synthesis reaction, an impure sample of aspirin was prepared from 2-hydroxybenzoic acid and ethanoic anhydride. The reaction mixture was heated for approximately 10 minutes. 

Aspirin can be made by reacting 2-hydroxybenzoic acid with ethanoic anhydride as follows ... 

There are four ethyl ethanoate, ethanamide, ethanoyl chloride, and ethanoic anhydride. ... 

ACETIC ANHYDRIDE Ethanoic Anhydride Corrosive Material, II 2 2 1 W... 

The methanal and ammonia that split off the cage structure during the reaction with nitric acid need not be wasted. In the large-scale manufacture of cyclonite, a combination of nitric acid, ammonium nitrate, and ethanoic anhydride is used, which results in full utilization of the methanal and ammonia ... 

Exercise 17-11 The direct halogenation of aldehydes under either acidic or basic conditions is complicated by side reactions involving either oxidation of the aldehyde —CHO group or additions to the—CH—0 double bond. Therefore the synthesis of a-halo aldehydes by the procedure described for ketones is not of much practical value. a-Haio aldehydes can be prepared indirectly from the enol ethanoate of the aldehyde. The enol ethanoate is made by treating the aldehyde with ethanoic anhydride and potassium ethanoate. The overall sequence follows ... 

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