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PDGF beta

Kim JH, Jin YR, Park BS, Kim TJ, Kim SY, Lim Y, Hong JT, Yoo HS, Yun YP. 2005. Luteolin prevents PDGF-BB-induced proliferation of vascular smooth muscle cells by inhibition of PDGF beta-receptor phosphorylation. Biochem Pharmacol 69 1715-1721. [Pg.130]

L. Ronnstrand, S. Mori, A. K. Amdsson, A. Eriksson, C. Wemstedt, U. Heilman, et al. Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor involvement in the interaction with phospholipase C-gamma. EMBOJ, 11 (11), 3911-3919, 1992. [Pg.20]

Sachinidis A, Seul C, Seewald S, Ahn H, Ko Y, Vetter H (2000) Green tea compounds inhibit tyrosine phosphorylation of PDGF beta-receptor and transformation of A172 human gUoblastoma. FEBS Lett... [Pg.111]

Other kinase receptors are serine/threonine kinases, protein kinases, and mitogen-activated protein (MAP) kinases. Insulin, transforming growth factor-beta (TGF- 8), and platelet-derived growth factor (PDGF) are the natural ligands that interact with kinase receptors. [Pg.44]

Fischer AN, Fnchs E, Mikula M, Huber H, Beug H, Mikulits W (2006). PDGF essentially links TGF beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression. Oncogene [Epub ahead of print]. [Pg.133]

Gotzmann J, Fischer AN, Zojer M, Mikula M, Proell V, Huber H et al (2006). A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene 25 3170-3185. [Pg.133]

Cantero, A. V., Portero-Otin, M., Ayala, V., Auge, N., Sanson, M., Elbaz, M., Thiers, J. C., Pamplona, R., Salvayre, R., and Negre-Salvayre, A. (2007). Methylglyoxal induces advanced glycation end product (ages) formation and dysfunction of PDGF receptor-beta Implications for diabetic atherosclerosis. FASEB J. 21,3096-3106. [Pg.136]

Rosenkranz S, Kazlauskas A. 1999. Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes. Growth Factors 16 201-216. [Pg.227]

Hellstrom M, Kalen M, Lindahl P, Abramsson A, Betsholtz C (1999) Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development, 126(14) 3047-3055. [Pg.267]

A. Eriksson, A. Siegbahn, B. Westermarlq C. H. Heldin, and L. Claesson Welsh. PDGF alpha- and beta-receptors activate unique and common signal transduction pathways. EMBOJ, 11 (2), 543-550,1992. [Pg.21]

Lindroos PN, Coin PG, Badgett A, et al. 1997. Alveolar macrophages stimulated with titanium dioxide, chrysotile asbestos, and residual oil fly ash upregulate the PDGF receptor-alpha on lung fibroblasts through an IL-1 beta-dependent mechanism. Am J Respir Cell Mol Biol 16 283-292. [Pg.295]

Majack RA, Majesky MW, Goodman LV (1990) Role of PDGF-A expression in the control of the vascular smooth muscle cell growth by transforming growth factor-beta. J Cell Biol 111 239-247... [Pg.314]

Isaka, Y., Fujiwara, Y., Ueda, N., Kaneda, Y., Kamada, T., and Imai, E. (1993) Glomerulosclerosis induced by in vivo transfection with TGF-beta or PDGF gene into rat kidney. /. Clin. Invest. 92, 2597-2601. [Pg.57]

PDGF-(3(3 Platelet-derived growth factor subunits beta beta... [Pg.1441]

The water extract of Buddieja qfficinalis (Buddlejaceae) inhibited vascular inflammation and atherosclerotic disorders. Recently, Tai et al. isolated several compounds from the flowers of the plant and tested their in vitro effects on the proliferation of rat aortic vascular smooth muscle cells (VSMCs). Among the tested compounds, two iridoids, namely, methylscutelloside (146) and methylcatalpol (147), showed significant inhibitory effects on homodimer platelet-derived growth factor beta polypeptide (PDGF-BB)-induced proliferation in rat aortic VSMCs. Methylscutelloside (146) decreased cell proliferation at 10, 30, and 50 pM, with inhibition of 39.1%, 42.0%, and 79.6%, respectively, while methylcatalpol showed significant inhibition (80%) only at 50 pM concentration. Their inhibitory effect on rat aortic VSMC proliferation may be useful for the treatment of atherosclerosis [153]. [Pg.3051]

Figure 5. Crosstalk mechanisms involving sphingosine 1-phosphate (SIP) or lysophosphatidic acid (LPA). GRK2, G-protein coupled receptor kinase 2. PDGF, platelet-derived growth factor. PDGFR, platelet-derived growth factor receptor. SIP, sphingosine 1-phosphate receptor 1. MAPK, mitogen-activated protein kinase, a., alpha subunit of the heterotrimeric inhibitory G-protein, G.. py, beta/gamma subunits of a heterotrimeric G-protein. Figure 5. Crosstalk mechanisms involving sphingosine 1-phosphate (SIP) or lysophosphatidic acid (LPA). GRK2, G-protein coupled receptor kinase 2. PDGF, platelet-derived growth factor. PDGFR, platelet-derived growth factor receptor. SIP, sphingosine 1-phosphate receptor 1. MAPK, mitogen-activated protein kinase, a., alpha subunit of the heterotrimeric inhibitory G-protein, G.. py, beta/gamma subunits of a heterotrimeric G-protein.
Chen YM, Wu KD, Tsai TJ, et al. Pentoxifylline inhibits PDGF-inducedproliteration of and TGF-beta-stimulated collagen synthesis by vascular smooth muscle cells. J Mol Cell Cardiol 1999 31 773-783. [Pg.238]

Warshamana GS, Corti M, Brody AR. TNF-alpha, PDGF, and TGF-beta(l) expression by primary mouse bronchiolar-alveolar epithelial and mesenchymal cells tnf-alpha induces TGF-beta(l). Exp Mol Pathol 2001 71(l) 13-33. [Pg.331]

See other pages where PDGF beta is mentioned: [Pg.68]    [Pg.227]    [Pg.227]    [Pg.68]    [Pg.227]    [Pg.227]    [Pg.159]    [Pg.337]    [Pg.358]    [Pg.360]    [Pg.363]    [Pg.396]    [Pg.125]    [Pg.339]    [Pg.219]    [Pg.360]    [Pg.257]    [Pg.97]    [Pg.98]    [Pg.438]    [Pg.439]    [Pg.140]    [Pg.178]    [Pg.102]    [Pg.208]    [Pg.526]    [Pg.529]    [Pg.1450]    [Pg.664]    [Pg.394]    [Pg.854]   


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