Parkinson group

D. B. Parkinson, Group-TransferPolymerisyation Applications, PEP Review No. 83-2-3, Stanford Research Institute, Menlo Park, Calif., 1984, p. 9. 

Our interest in quantum dot-sensitized solar cells (QDSSC) is motivated by recent experiments in the Parkinson group (UW), where a two-electron transfer from excitonic states of a QD to a semiconductor was observed [32]. The main goal of this section is to understand a fundamental mechanism of electron transfer in solar cells. An electron transfer scheme in a QDSSC is illustrated in Figure 5.22. As discussed in introduction, quantum correlations play a crucial role in electron transfer. Thus, we briefly describe the theory [99] in which different correlation mechanisms such as e-ph and e-e interactions in a QD and e-ph interactions in a SM are considered. A time-dependent electric field of an arbitrary shape interacting with QD electrons is described in a dipole approximation. The interaction between a SM and a QD is presented in terms of the tunneling Hamiltonian, that is, in... 

Basal ganglia are a group of subcortical nuclei which are essential for the coordination of movements (so-called extrapyramidal system). They include the caudate nucleus, putamen, globus pallidus, and lenti-form nucleus. Damage of the basal ganglia results in involuntary movements, as are observed in Parkinson s disease and Huntington s chorea. 

Among the most significant adverse reactions associated with the antipsychotic dm are the extrapyramidal effects. The term extrapyramidal effects refers to a group of adverse reactions occurring on the extrapyramidal portion of the nervous system as a result of antipsychotic drains. This part of the nervous system affects body posture and promotes smooth and uninterrupted movement of various muscle groups. Antipsychotics disturb the function of the extrapyramidal portion of the nervous system, causing abnormal muscle movement. Extrapyramidal effects include Parkinson-like symptoms (see Chap. 29), akathisia, and dystonia (see Display 32-1). 

Ciraulo DA, Jaffe JH Tricyclic antidepressants in the treatment of depression associated with alcoholism. Clin Psychopharmacol 1 146—150, 1981 Ciraulo DA, Nace E Benzodiazepine treatment of anxiety or insomnia in substance abuse patients. Am J Addict 9 276—284, 2000 Ciraulo DA, Barnhill JG, Jaffe JH, et al Intravenous pharmacokinetics of 2-hydroxy-imipramine in alcoholics and normal controls. J StudAlcohol 51 366-372, 1990 Ciraulo DA, Knapp CM, LoCastro J, et al A benzodiazepine mood effect scale reliability and validity determined for alcohol-dependent subjects and adults with a parental history of alcoholism. Am J Drug Alcohol Abuse 27 339—347, 2001 Collins MA Tetrahydropapaveroline in Parkinson s disease and alcoholism a look back in honor of Merton Sandler. Neurotoxicology 25 117-120, 2004 COMBINE Study Research Group Testing combined pharmacotherapies and behavioral interventions in alcohol dependence rationale and methods. Alcohol Clin Exp Res 27 1107-1122, 2003a... 

It is generally aeeepted that COMT is an extraeellular enzyme in the CNS that catalyses the transfer of methyl groups from S-adenylmethionine to the meta-hydroxy group of the eateehol nueleus. Until recently the only inhibitors of this enzyme were pyragallol and eateehol whieh were too toxic for clinical use. Now other inhibitors have been developed, e.g. entaeapone and tolcapone, but these are used mainly to protect dopa (also a catecholamine) from O-methylation, in the treatment of Parkinson s disease (Chapter 15). 

Goetz, Christopher G., Joanne Wuu, Michael P. McDermott, Charles H. Adler, Stanley Fahn, Curt R. Freed, Robert A. Hauser, Warren C. Olanow, Ira Shoulson, P. K. Tandon, Parkinson Study Group and Sue Leurgans, Placebo Response in Parkinson s Disease Comparisons among 11 Trials Covering Medical and Surgical Interventions , Movement Disorders 5 (2008) 690-99... 

Another occupational study failed to reveal any significant correlation between occupational lead exposure and diastolic and systolic blood pressure (Parkinson et al. 1987). After controlling for known risk factors (e.g., age, education, income, cigarette usage, alcohol consumption, and exercise), the association between exposure and blood pressure was found to be small and nonsignificant when a group of randomly selected white battery plant workers (n=270) was compared to 158 nonexposed workers. 

Historically, stimulants that increase the activity of catecholamines are the oldest drugs in this group (Jones et al. 1973). Reduction in DA activity has been related to a reduction in wakefulness lesions of DA cell groups in the ventral tegmentum that project to the forebrain have been shown to induce a marked reduction in behavioral arousal in rats (Jones et al. 1973), and patients with Parkinson s disease, who exhibit consistent DA lesions, experience severe sleep disorders (Rye and Jankovic 2002). 

Basal ganglia A group of networked structures in the brain which control voluntary movement. Two basal ganglia disorders are Huntington s disease and Parkinson s disease. 

Recently, seven polymorphisms have been identified in ADH7, one of which is in the promoter. These polymorphisms were grouped into five alleles in a Swedish population, and one of the alleles was associated with Parkinson s disease [36]. The potential association of polymorphisms with alcoholism or its sequelae would be important. 

Anon. Datatop A multicenter controlled clinical trial in early Parkinson s disease. Parkinson study group. Arch. Neurol. 46 1052-1060,1989. 

A crucial achievement significantly stimulated the development of the investigation in the field of homogeneous enantioselective catalysis. The Knowles group established a method for the industrial synthesis of I-DOPA, a drug used for the treatment of Parkinson s disease. The key step of the process is the enantiomeric hydrogenation of a prochiral enamide, and this reaction is efficiently catalyzed by the air-stable rhodium complex [Rh(COD)((PP)-CAMP)2]BF4 (Scheme 1.12). 

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