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Pancreatic tumors antigens

Tumor type colorectal NSCLC pancreatic, breast Antigen VEGE Tumor type colorectal cancer Angiogenesis Bevacizumab (humanized) None None... [Pg.902]

Fransson, J., S. Ek, R Ellmark, E. Soderlind, C. A. Borrebaeck and C. Fumbling (2004). Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics. Ccmcer Lett 208(2) 235-242. [Pg.126]

The oncolytic viruses include adenovirus, measles, reovirus, vesicular stomatitis virus (VSV),HSV,poxvirus, and vaccinia. Specific examples include (1) ONYX-015, which is an adenoviral oncolytic virus, administered to patients with liver metastases of colorectal cancer and pancreatic cancer [29], (2) Reolysin, which is an oncolytic reovirus administered to patients with glioma [30], and (3) MV-CEA, which is an oncolytic measles virus expressing carcinoembryonic antigen, administered to patients with ovarian cancer [31]. Some oncolytic viruses are wild type and are apparently not pathogenic in humans, such as the Newcastle disease virus (NDV), which is an RNA avian paramyxovirus. PV701, a naturally attenuated, replication-competent strain of NDV, has been administered to patients with advanced solid tumors [32], The applicability of oncolytic viruses as a therapy for clinical oncology trials is due to their potential selectivity the ability to kill tumor cells but not normal cells. However, the level of attenuation of viral replication in normal cells is limited for most oncolytic vectors. [Pg.727]

Weihing RR, Shintaku IP, Geller SA, Petrovic LM. Hepatobiliary and pancreatic mucinous cystadenocarcinomas with mesenchymal stroma analysis of estrogen receptors/progesterone receptors and expression of tumor-associated antigens. Mod Pathol. 1997 10 372-379. [Pg.582]


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See also in sourсe #XX -- [ Pg.541 , Pg.542 , Pg.543 ]




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