Packed columns preliminary design

Final design of packed columns should be performed by experts, but the layman is often required to provide preliminary designs for studies. This packed column section provides the information necessary for such estimates. 

The design of simulated moving bed chromatography and its application to the separation of cycloheptanone and cyclopentanone as test substances to validate the system for subsequent chiral chromatography has been described.27 Briefly, eight silica-packed columns were hooked up in series to form a cyclic flow path. On the first pair, preliminary separation of the components was performed, with the less-retained raffinate being directed to waste. Following the second pair of columns, eluent was added. After the... 

Preliminary design work has been done on a process to recover a valuable product from an effluent gas stream. The gas will be scrubbed with a solvent in a packed column the recovered product and solvent separated by distillation and the solvent cooled and recycled. The major items of equipment that will be required are detailed below. 

The preliminary design provides a basis for deciding which manufacturers, which packings, and what packing sizes should be considered. The preliminary diameter and bed height provide a suitable basis for comparing quotes. An apples-to-apples comparison of different quotes is extremely difficult when column height and diameter vary. 

Include all relevant process information as well as the preliminary column diameter, bed heights, and spaces between beds. Request a base quote using the preliminary design. Do not specify packing type and size, but list any constraints such as we require random packing, 1.5 to 2.5 inch nominal size or equivalent. Request the suppliers to take exception to any details that in their opinion will not work. 

For preliminary method scouting STREAMLINE media is used in packed bed mode in an XK 16 or XK 26 chromatography column. When used in expanded bed mode the media must be packed in specially designed STREAMLINE columns, following the manufacturer s instructions. 

This chapter is not a shortcut to becoming an expert. However, upon conpletion of this chapter you should be able to finish a preliminary design of the column internals for both staged and packed columns, and you should be able to discuss distillation designs intelligently with the e5q>erts. 

For specific final performance sizing of a distillation column using Norton s Intalox structured packing the designer is referred to the manufacturer s technical representatives, and should not assume the preliminary results obtained from any manufacturer s bulletin included here will necessarily serve as a final design. As a preliminary examination of a design problem (used by permission of Norton Chemical Process Products) ... 

---