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P388 murine leukaemia cells

Peloruside A 14 (Scheme 6.1 Part 2) was isolated from a New Zealand Mycale hentschei marine sponge and initially showed activity against P388 murine leukaemia cells at 10 ng/mL.98 Peloruside s cytotoxicity profile and structural similarity to bryostatin led to the examination of protein kinase C (PKC) as a possible mode of action.242 This was determined to be incorrect and it was soon established that the remarkable activity of peloruside was through the stabilisation of microtubules at a site distinct from the taxoid site.243... [Pg.184]

P388 murine leukaemia cells with an IC50 value of 7.5 p.g/ml. [Pg.1191]

Ramu A, Spanier R, Rahamimoff H, Fuks Z. Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells, BrJCancer ( 9S4) 50, 501-7. [Pg.611]

Alkaloid from the tunicate Ritterella tokioka. Shows potent cytotoxicity against P388 murine leukaemia cells. Glassy solid, [aj +112.0 (c, 0.1 in MeOH). [Pg.339]

KB = human epidermoid earcinoma cells HeLa = human eervieal carcinoma cells H210 = murine lymphoma cells P388 = mouse leukaemia cells... [Pg.384]

A pronounced effect in vivo was also observed after injection of either formaldehyde-treated RNA or polyadenylic acid into the peritoneal cavity of the mouse where the murine leukaemia cell line (P388) was growing as an ascitic tumour [12]. [Pg.506]

See other pages where P388 murine leukaemia cells is mentioned: [Pg.52]    [Pg.63]    [Pg.620]    [Pg.732]    [Pg.1185]    [Pg.52]    [Pg.63]    [Pg.620]    [Pg.732]    [Pg.1185]    [Pg.326]    [Pg.17]    [Pg.231]    [Pg.781]    [Pg.153]    [Pg.179]    [Pg.61]    [Pg.781]    [Pg.752]    [Pg.166]    [Pg.115]    [Pg.96]    [Pg.69]   
See also in sourсe #XX -- [ Pg.92 ]

See also in sourсe #XX -- [ Pg.92 ]



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Leukaemia

Leukaemias leukaemia

Murine

Murine cells

P388

P388 murine

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