Oxides biomaterials

Chen H, Zhang Z, Chen Y, Brook MA, and Sheardown H. Protein repeUant silicone surfaces by covalent immobilization of poly(ethylene oxide). Biomaterials, 2005, 26, 2391-2399. 

Badiger, MV McNeill, ME Graham, NB, Porogens in the Preparation of Microporous Hydrogels based on Poly(ethylene oxides). Biomaterials 14,1059, 1993. 

Chen, H., Zhang, Z., Chen, Y., Brook, M. A., Sheardown, H. Protein Repellant Silicone Surfaces by Covalent Immobilization of Poly(Ethylene Oxide), Biomaterials 2005,26, 2391. 

E. Brinlmian, A. Foot, L. Van der Does, and A. Bantjes. Platelet deposition on copolyether urethane modified with poly(ethylene oxide). Biomaterials 11 200-205 (1990). 

F. Variola et al. Tailoring the surface properties of Ti6A14V by controlled chemical oxidation. Biomaterials 29 (2008) 1285-1298. 

Costa L., M.P. Luda, L. TrossarelU, et al. 1998a. Oxidation in orthopaedic UHMWPE sterilized by gamma-radiation and ethylene oxide. Biomaterials 19 659-668. 

Y. Oshida, R. Sachdeva, and S. Miyazaki, Changes in contact angles as a function of time on some pre-oxidized biomaterials. Journal of Materials Science Materials in Medicine, 3, 306-312 (1992). 

Costa L, Luda MP, Trossarelli L, Brach del Prever EM, Crova M, GalUnaro P. Oxidation in Orthopaedic UHMWPE Sterilized by gamma-radiation and ethylene oxide. Biomaterials. 1998 19 659-68. 

Duan, X., Lewis, R.S. Improved haemocompatibUity of cysteine-modified polymers via endogenous nitric oxide. Biomaterials 23(4), 1197-1203 (2002)... 

R. Lerf, D. Zurbriigg, D. Delfosse. Use of vitcunin E to protect cross-hnked UHMWPE from oxidation. Biomaterials 31(13), 3643-3648, May (2010). 

Ko Y.G. et al. 2001. Immobilization of polyfethylene glycol) or its sulfonate onto polymer surfaces by ozone oxidation. Biomaterials 22 2115-23. 

Biomaterials with Low Thrombogenicity. Poly(ethylene oxide) exhibits extraordinary inertness toward most proteins and biological macromolecules. The polymer is therefore used in bulk and surface modification of biomaterials to develop antithrombogenic surfaces for blood contacting materials. Such modified surfaces result in reduced concentrations of ceU adhesion and protein adsorption when compared to the nonmodifted surfaces. 

Lubricious Coatings for Biomaterials. Coatings of poly(ethylene oxide) when dry are tactile. If brought into contact with water, the poly(ethylene oxide) hydates rapidly and forms a lubricious coating. This type of technology is of great interest for biomedical devices introduced into the human body, such as catheters and endotracheal tubes, and for sutures (114—117). 

Preparation of polyfethylene oxide) (PEO) and poly(arylene ether) based hydrophilic-hydrophobic block copolymer is of special interest because PEO has been proven to be particularly reliable and versatile for the surface modification of biomaterials. The first poly(ediylene oxide)-/ /oc/c-polysulfonc (PEO-fc-PSF) copolymers were reported by Aksenov et al.217 They employed diisocyanate chemistry to link hydroxy-terminated sulfone oligomers and polyfethylene... 

Bryant, S.J. and Anseth, K.A., The effects of scaffold thickness on tissue engineered cartilage in photocrosslinked poly(ethylene oxide) hydrogels. Biomaterials, 22, 619-626, 2001. 

Muller, K., Skepper, J.N., Posfai, M., Trivedi, R., Howarth, S., Corot, C., Lancelot, E., Thompson, P.W., Brown, A.P., and Gillard, J.H. (2007) Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages invitro. Biomaterials, 28 (9), 1629-1642. 

Kamitakahara, M., Kawashita, M., Miyata, N., Kokubo, T. and Nakamura, T. (2003) Apatite-forming ability and mechanical properties of CaO-free poly (tetramethylene oxide) (PTMO)-TiC>2 hybrids treated with hot water. Biomaterials, 24, 1357-1363. 

Harper, G.R., Davis, S.S., Davies, M.C., Norman, M.E., Tadros, T.F., Taylor, D.C., Irvin, M.P., Waters, J.A., and Watts, J.F. (1995) Influence of surface coverage with poly(ethylene oxide) on attachment of sterically stabilized microspheres to rat Kupffer cells in vitro. Biomaterials 16, 427-439. 

M.C. Frost, M.M. Reynolds, and M.E. Meyerhoff, Polymers incorporating nitric oxide releasing/gener-ating substances for improved biocompatibility of blood-contacting medical devices. Biomaterials 26, 1685-1693 (2005). 

The first enzyme biosensor was a glucose sensor reported by Clark in 1962 [194], This biosensor measured the product of glucose oxidation by GOD using an electrode which was a remarkable achievement even though the enzyme was not immobilized on the electrode. Updark and Hicks have developed an improved enzyme sensor using enzyme immobilization [194], The sensor combined the membrane-immobilized GOD with an oxygen electrode, and oxygen measurements were carried out before and after the enzyme reaction. Their report showed the importance of biomaterial immobilization to enhance the stability of a biosensor. 

Biomass Research and Development Initiative iolnitiative), 24 192 Biomaterial coatings, ethylene oxide polymers in, 70 688 Biomaterials, 3 707-709. See also Biomaterials, prosthetics, and biomedical devices bioresorbable polymers, 3 735-740... 

Worm end products, 18 646 Worsted wool-processing system, 26 383-384, 385-386 Worsted yarn, 11 178 Wort, 3 563, 564, 574, 575, 583 separation, 3 578-579 Wound closure, suture size and, 24 216 Wound closure biomaterials, 24 205. See also Sutures Wound dressings cotton smart, 3 31 ethylene oxide polymers in, 10 687 hydrogels in, 13 751-752 Woven fabrics, 11 178 dyeing, 9 170-171 Woven flax fibers, 11 594 Woven plastic bags, 18 12 Wovens... 

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