Other Reporting Requirements

Reporting of suspicions of dependence should be to the national adverse drug reaction centre, but other reporting requirements under national laws must be followed. 

Other reporting requirements may be instituted at the d i rect i on of the PSOs. 

Property Owners You are not required to report if you merely own real estate on which a facility covered by this rule is located that Is, you have no other business interest in the operation of that facility (e.g., yourcompany owns an industrial park). The operator of that facllKy, however. Is subject to reporting requirements. 

Step 2 allows you to identify uses of the chemical or chemical category that were included In Step 1 but that are exempt under section 313. Do not include In Step 2 exempt forms of the chemical not included in the calculations in Step 1. For example. If you did not report the freon contained in the building s air conditioners in Step 1, you would not include the amount as exempt in Step 2. Step 2 is intended for use when one form or use of the chemical is exempt while others forms require reporting. Note the type of exemption for future reference. Also identify, if applicable, the fraction or percentage of the chemical present that Is exempt. Add the amounts in each activity to obtain a subtotal for exempted amounts of the chemical or chemical categories at the facility. 

All data available at your facility must be utilized to calculate treatment efficiency and influent chemical concentration. You areDfll required to collect any new dataforthe purposes of this reporting requirement. If data are lacking, estimates must be made using best engineering judgment or other methods. 

If you are unsure if you are subject to the reporting requirements of Section 313, or need more information, call the EPA Emergency Planning and Community Right-To-Know Information Hotline (800) 535-0202 or (202) 479-2449 (in Washington D.C. or Alaska). Your other suppliers should also be notifying you if section 313 chemicals are In the mixtures and trade name products they sell to you. 

Industrial Pollutant Monitoring for recordkeeping and report generation and Process Monitoring/Rcporting for process reports and other reports. Each requires 512K memory and lOMeg hard disk. 

As part of planning your company s PSM system roll-out (Chapter 7), you have established a number of benchmarks and parameters for the installation process. For example, pilot testing should yield realistic estimates for individual facilities schedule, staffing, and other resource requirements, as well as workable formats for reporting. The installation plan you developed should derive from these results, adapting them to the full range of your company s operations. 

The N-substituted aminoacids required could be prepared by microwave-assisted reductive amination of aminoacid methyl esters with aldehydes, and although in the Westman report soluble NaBH(OAc)3 was used to perform this step, other reports have shown how this transformation can be performed in using polymer-supported borohydrides (such as polymer-supported cyanoborohydride) under microwave irradiation [90]. An additional point of diversity could be inserted by use of a palladium-catalyzed reaction if suitably substituted aldehydes had been used. Again, these transformations might eventually be accomplished using supported palladium catalysts under microwave irradiation, as reported by several groups [91-93]. 

While other programs require modification of the actual code in changing the polymer, spectra, or model, only changes in the user database is required here. Changes in the program since a brief report (22) in 1985 include improvement of the menu structure, added utilities for spectral manipulations, institution of demo spectra and database. Inclusion of Markov statistics, and automation for generation of the coefficients in Equation 1. Current limitations are that only three models (Bernoul llan, and first- and second-order Markov) can be applied, and manual input Is required for the N. A. S. L.. 

Accountability and transparency have several aspects reporting to and control by supervisory bodies clarity and openness of procedures criteria for decision-making and decisions made and existence of systems for complaint and appeal. Accountability and transparency can be evaluated by examining, in particular reporting requirements, external reviews of the authority s performance frequency of publications and content of website (and other means of communication between the DRA, the public and the regulated parties) bodies to which complaints are directed and appeals procedures. However, the individual details of these elements of regulation make quantitative comparison difficult. 

The (EDT-TTF-I)2Br salt described above [36] and the 1 1 (TTFI4)I salt reported by Gompper [51] were the only structurally characterized salts with simple halide anions until Imakubo recently described an extensive series of Cl" and Br" salts from several ortho-diiodo tetrathiafulvalene, tetraselena-fulvalene and dithiadiselenafulvalene derivatives (Scheme 8) [62], The X-ray crystal structure analysis of the nine salts described there show a variety of halogen bonded motifs, demonstrating the adaptability of the supramolecu-lar interactions to other structural requirements imposed by the nature of the heteroatoms (O, S, Se) in the TTF frame. Indeed, in (EDT-TTF-l2)2X-(H20)2 (X = Cl, Br), a bimolecular motif (Fig. 6) associates two partially oxidized EDT-TTF-I2 molecules with one Br" anion and one water molecule. 

Maruoka and co-workers recently reported an example of a Zr-catalyzed cyanide addition to an aldehyde [64]. As is also illustrated in Scheme 6.20, the reaction does not proceed at all if 4 A molecular sieves are omitted from the reaction mixture. It has been proposed that the catalytic addition proceeds through a Meerwein—Ponndorf—Verley-type process (cf. the transition structure drawn) and that the crucial role of molecular sieves is related to facilitating the exchange of the product cyanohydrin oxygen with that of a reagent acetone cyanohydrin. The example shown is the only catalytic example reported to date the other reported transformations require stoichiometric amounts of the chiral ligand and Zr alkoxide. 

Over the years, there have been numerous reports of oxidase preparations that contain polypeptide components, additional to those described above. As yet no molecular probes are available for these, and so their true association with the oxidase is unconfirmed. There are many reports in the literature describing the role of ubiquinone as an electron transfer component of the oxidase, but its involvement is controversial. Quinones (ubiquinone-10) have reportedly been detected in some neutrophil membrane preparations, but other reports have shown that neither plasma membranes, specific granules nor most oxidase preparations contain appreciable amounts of quinone, although some is found in either tertiary granules or mitochondria. Still other reports suggest that ubiquinone, flavoprotein and cytochrome b are present in active oxidase preparations. Thus, the role of ubiquinone and other quinones in oxidase activity is in doubt, but the available evidence weighs against their involvement. Indeed, the refinement of the cell-free activation system described above obviates the requirement for any other redox carriers for oxidase function. 

There are other differences between RMP and PSM. This can be seen in the reporting requirements and in some of the different terms and definitions used by USEPA in RMP. To begin with, in regard to reporting requirements, under PSM OSHA requires the covered facility to comply with all applicable paragraphs. This compliance is expected to be completed by the covered facility but there is no reporting requirement (i.e., submission of a formal written document showing that compliance has been effected is not required under PSM). 

Records and reports require that any procedures or other records required to be maintained in compliance with these Good Compounding Practices shall be retained for the same period of time as each State requires for the retention of prescription files. 

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