Original paradigm

It should be noted that the Bayesian conception of probability of a hypothesis and the Bayesian procedure for assessing this probability is the original paradigm for probabilistic... 

Evidence supporting the original paradigm of lignin in wood as a random, three-dimensional network polymer is reviewed. More recent results which do not fit this simple picture are discussed. A modified paradigm is proposed in which lignin in wood is comprised of several types of network which differ from each other both ultrastructurally and chemically. When wood is deligni-fied, the properties of the macromolecules made soluble reflect the properties of the network from which they are derived. 

This book may reveal some yet vmexplored connections between Statistics and Algebra, as work on QSAR by Ihe original paradigm of relation molecular structure-property/activity and Ihe basic Physics at sub-atomic level, namely the involvement of bondons (also introduced by him in previous volumes of this Quantum Nanochemistry set) in chemical observables, such as reactivity/stability or biological activity, with spatial complementarity being an important premise in the effector-... 

The fluid mechanics origins of shock-compression science are reflected in the early literature, which builds upon fluid mechanics concepts and is more concerned with basic issues of wave propagation than solid state materials properties. Indeed, mechanical wave measurements, upon which much of shock-compression science is built, give no direct information on defects. This fluids bias has led to a situation in which there appears to be no published terse description of shock-compressed solids comparable to Kormer s for the perfect lattice. Davison and Graham described the situation as an elastic fluid approximation. A description of shock-compressed solids in terms of the benign shock paradigm might perhaps be stated as ... 

It is therefore easy to see why this current drug safety paradigm, with its lack of standards in data collection and analysis, hinders the analysis of adverse events. Without data standards in place, it is difficult to build practical, reusable tools for systematic safety analysis. With no standard tools, truly standardized analyses cannot occur. Reviewers may forget their initial analytical processes if they are not using standardized data and tools. Comprehensive reproducibility and auditability, therefore, become nearly impossible. In practice, the same data sets and analytical processes cannot be easily reused, even by the same reviewers who produced the original data sets and analyses. Not using standardized tools slows the real-time systematic analysis... 

Aromatic nitrosation with nitrosonium (NO + ) cation - unlike electrophilic nitration with nitronium (NO ) cation - is restricted to very reactive (electron-rich) substrates such as phenols and anilines.241 Electrophilic nitrosation with NO+ is estimated to be about 14 orders of magnitude less effective than nitration with N02+. 242 Such an unusually low reactivity of NO+ toward aromatic donors (as compared to that of NO ) is not a result of the different electron-acceptor strengths of these cationic acceptors since their (reversible) electrochemical reduction potentials are comparable. In order to pinpoint the origin of such a reactivity difference, let us examine the nitrosation reaction in the light of the donor-acceptor association and the electron-transfer paradigm as follows. 

It is of interest to analyze the paradigm shift caused by the SMDS process in context of the original Shell design objectives (refer to Section 18.8) and the current situation. 

Today, it is generally thought that the Universe is open, by which it is meant that the expansion is eternal, and indeed, even accelerating. This strikes at the very heart of the old paradigm of eternal return. This announcement of a one-way diaspora originates from a certain type of exploding star, visible from... 

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