Response surface methodology optimization using

Enzymatic hydrolysis of waste paper process optimization using response surface methodology... 

For instance, Yadav and Ahuja prepared nanoparticles using gum cordia as the polymer and to evaluate them for ophthalmic delivery of fluconazole. A w/o/w emulsion containing fluconazole and gum cordia in aqueous phase, methylene chloride as the oily phase, and dioctyl sodium sulfosuccinate and polyvinyl alcohol as the primary and secondary emulsifiers, respectively, were cross-linked by the ionic gelation technique to produce a fluconazole-loaded nanoreservoir system. The formulation of nanoparticles was optimized using response surface methodology. Multiple response simultaneous optimizations using the desirability approach were used to find optimal experimental conditions. The optimal conditions were found to be concentrations of gum cordia (0.85%, w/v), di-octyl sodium sulfosuccinate (9.07%, w/v), and fluconazole (6.06%, w/v). On comparison of the optimized nanosuspension formulation with commercial formulation, it was found to provide comparable in vitro corneal permeability of... 

Sun, W.-J. Zhao, H.-X. Cui, F.-J. Li, Y.-H. Yu, S.-L. Zhou, Q. Qian, J.-Y. Dong, Y. D-isoascorbylpalmitate Lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology. Chemistry Central Journal, 2013, 7, 114-127. 

Hameed, B. H., Tan, I. A. W., Ahmad, A. L. Preparation of oil palm empty fiuit bunch-based activated carbon for removal of 2, 4, 6-trichlorophenol Optimization using response surface methodology. Journal of Hazardous Materiab 2009,164(2), 1316-1324. 

Cheong LZ, Ariffin N, Tan CP, et al. 2007. Production of a diacylglycerol enriched palm olein using lipase-catalyzed partial hydrolysis optimization using response surface methodology. Food Chem 105 1614-1622. 

Peng L, Xu X, Mu H, H0y CE, Adler-Nissen. 2002. Production of structured phosphoUpids by Upase catalyzed addolysis optimization using response surface methodology. J Enzym Microb Technol 31 523-532. 

Jahinil, M.I., Koh, W., et al., 2014. Biodiesel production from non-edible beauty leaf (Ccdo-phyllum inophyllum) oil process optimization using response surface methodology (RSM). Energies 7 (8), 5317—5331. 

Boey, P.-L., et al., 2011. Utilization of waste cockle shell (Anadara granosa) in biodiesel production from pahn olein optimization using response surface methodology. Fuel 90 (7), 2353—2358. Available at http //www.sciencedirect.com/science/article/pii/S001623611 100130X (accessed 14.02.15.). 

HaUm, S.E.A., Kamaruddin, A.H., Eemando, W.J.N., 2009. Continuous biosynthesis of biodiesel from waste cooking pabn oil in a packed bed reactor optimization using response surface methodology (RSM) and mass transfer studies. Bioresource Technology 100, 710-716. 

Gonzalez, M. et al.. Optimizing conditions for the extraction of pigments in cochineals Dactylopius coccus Costa) using response surface methodology, J. Agric. Food Chem., 50, 6968, 2002. 

Garrote, R. L., Coutaz, V. R., Luna, J. A., Silva, E. R., Bertone, R. A. (1993). Optimizing processing conditions for chemical peeling of potatoes using response surface methodology. J. Food Sci., 58, 821-826. 

Nazzal, S., Nutan, M., Palamakula, A., Shah, R., Zaghloul, A.A., and Khan, M.A. (2002) Optimization of a self-nanoemulsi ed tablet dosage form of Ubiquinone using response surface methodology effect of formulation ingredientslnt. J. Pharm., 240 103-114. 

Ushakumari, S. R., Rastogi, N. K., and Malleshi, N. G. (2007). Optimization of process variables for the preparation of expanded millet using response surface methodology. ]. Food Eng. 82,35-42. 

Sastry, S. V., Reddy, I. K., and Khan, M. A. Atenolol gastrointestinal therapeutic system optimization of formulation variables using response surface methodology. J. Contr. Rel. 45(2) 121-130, 1997. 

Sukigara, S., Gandhi, M., Ayutsede, J., Micklus, M., and Ko, F. "Regeneration of Bombyx mori silk by electrospinning. Part 2. Process optimization and empirical modeling using response surface methodology". Polymer 45(11), 3701-3708 (2004). 

Li, W., Du, W., and Liu, D. 2007. Optimization of whole cell-catalyzed methanolysis of soybean oil for biodiesel production using response surface methodology. /. Mol. Catal. B Enzym., 45,122-127. 

Ghafoor K. Park J. Choi Y. 2010. Optimization of supercritical fluid extraction of bioactive compounds from grape (Vitis labrusca B.) peel by using response surface methodology. Iimov. Food Sci. Emerg. Tech. 11 485-490. 

Lee, J.S. Ye, L. Landen, W.O. Jr. Eitenmiller, R.R. 2000. Optimization of an extraetion procedure for the quantification of vitamin E in tomato and broccoli using response surface methodology. J. Food Comp. Anal. 13 45-57. 

OPTIMIZATION METHODS USING RESPONSE SURFACE METHODOLOGY... 

Wang, S., Chen, F., Wu, J., Wang, Z., Liao, X., and Hu, X. (2007). Optimization of pectin extraction assisted by microwave from apple pomace using response surface methodology.. Food Eng. 78, 693-700. 

These principles formed the basis for producing high quality carrots and potatoes by a process of biopolymer infusion followed by high temperature short time fluidized bed dehydration. Infused biopolymers was shown to penetrate intracellular spaces and cell walls and may contribute to reduced cell collapse in the dehydration process. Deposition of infused biopolymer within the cells was elucidated using a convalently bound complex of biopolymer and colored dye which was visible upon histochemical examinations under a microscope. The dehydration process was optimized with response surface methodology. The resulting products have excellent quality, high rehydration ratio and a puffed structure. 

G. "Optimization of Gonversion of Waste Rapeseed Oil with High PEA to Biodiesel Using Response Surface Methodology." Renewable Energy 33 (2008) 1678-84. 

Saval S, Pablos L, Sanchez S (1993) Optimization of a culture medium for streptomycin production using response-surface methodology. Bioresour Technol 43 19-25... 

K, A, Abu-Izza, L. Garcia-Contreras, D, R, Lu, Preparation and evaluation of sustained release AZT-loaded rnicrospheres optimization of the release characteristics using response surface methodology. J. Pharm. Sci. 82(2) 144-149, 1996. 

Optimization. The influence of the reaction parameters on the yield of the reaction were studied using response surface methodology (RSM). A central composite design was used and both canonical analysis of the second-order equation and discussion of the isoresponse curves were used for the interpretation of the results. 

Su SN, Nie HL, Zhu LM, Chen TX. Optimization of adsorption conditions of papain on dye affinity membrane using response surface methodology. Bioresour. Technol. 2009 100 2336-2340. 

Optimization of the Synthesis of Urea-Formaldehyde Resins using Response Surface Methodology... 

Li, C., Bai, J., CaL Z., Ouyang, F. (2002). Optimization of a cultural medium for bacteriocin production by Lactococcus lactis using response surface methodology. Journal of Biotechnology, 95(1), 27-34. 

Wang LJ, Luo ZL, Shahbazi A. (2013). Optimization of simultaneous saccharification and fermentation for the production of ethanol from sweet sorghum (Sorghum bicolor) bagasse using response surface methodology. Ind Crop Prod, 42, 280-291. 

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