Omic

J. E. Ashton and J. M. Whitney, Theory of Laminated Plates, Te omic, Westport, Connecticut, 1970, Chapter Vii. ... 

Cln ome yellow, 43 Cln omic acetate, 41 Cln omic acid, 41 Cln omic chloride, 42... 

Examples of biomarker assays operating at different levels are given in Table 4.2. The recent development of omics technology should provide strong support to this approach (Box 4.3). Microarray analysis, for instance, can give a time-related sequence of gene responses that relate to the cellular changes of toxicity. 

Recent rapid technological advances have spawned a host of new terms that have caused confusion not only to interested laypeople but even to members of the scientific community. Many recently defined omics represent a case in point. The term genome was proposed by Hans Winkler in 1920 to describe the complete set of genes for a particular species (Snape et al. 2004 van Straalen and Roelofs 2006). Much later the term genomics appeared in the title of a journal (see, for example, McKusick 1997). Genomics has been defined as the study of how the genome translates into biological functions (Snape et al. 2004). 

In the summary of the aforementioned report, the authors recommend, as did earlier reviewers of this subject, the development and evaluation of a tiered testing strategy for neurotoxicity. The further development of in vitro models for establishing mechanisms of neurotoxicity should be part of this strategy. Full consideration should also be given to advances in the omics and other technological fields. 

Coverage of the use of biomarkers to study the effects of pollutants and the importance of new technologies, such as the "omics"... 

Thongboonkerd V. Genomics, proteomics and integrative omics in hypertension research. Curr Opin Nephrol Hypertens 2005 14 133-9. 

Sauro HM, Hucka M, Finney A, Wellock C, Bolouri H, Doyle J, et al. Next generation simulation tools the Systems Biology Workbench and BioSPICE integration. Omics 2003 7 355-72. 

Fostel J, Choi D, Zwickl C, Morrison N, Rashid A, Hasan A, et al. Chemical Effects in Biological Systems—Data Dictionary (CEBS-DD) a compendium of terms for the capture and integration of biological study design description, conventional phenotypes and omics data. Toxicol Sci 2005 88 585-601. 

Chaussabel D. Biomedical literature mining challenges and solutions in the omics era. Am J Pharmacogenet 2004 4 383-93. 

Figure 11.1 Schematic of omic expression, showing some prominent events that accompany the respective omic component of the cell.

Vemuri, G.N. and Aristidou, A.A. (2005) Metabolic engineering in the -omics era elucidating and modulating regulatory networks. Microbiology and Molecular Biology Reviews, 69, 197-216. 

Discussion of the use of omics technology to detect hazards and inform the regulatory process... 

Each of the -omics (Fig. 10.2) areas focuses on one group of bio molecule which is in itself structurally consistent. Each group requires quite different methods of preparation, handling, and analyzing. For very complex groups of biomolecules such as proteins, which can carry various modifications, subomics have formed. They deal with... 

Figure 10.1. "Omics" technologies investigate the different biomolecules in a cell, tissue, or other defined biological system in order to elucidate function.

An omics is an English neologism referring to a field of study in biology and biochemistry, ending in the suffix -omics, such as genomics or proteomics. 

Figure 10.2. Definition of-omics and -omes. From Wikipedia.

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