Oligonucleotides gene microarrays

Matsuki T, Hori G, Furuichi T. Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system. Brain Res Mol Brain Res 2005 136(l-2) 231-254. 

Kasamatsu A, Endo Y, Uzawa K, Nakashima D, Koike H, Hashitani S, et al. Identification of candidate genes associated with salivary adenoid cystic carcinomas using combined comparative genomic hybridization and oligonucleotide microarray analyses. Int J Biochem Cell Biol 2005 37 1869-80. 

Nishizuka, S., Winokur, S.T., Simon, M., Martin, J., Tsujimoto, H., and Stanbridge, E.J., Oligonucleotide microarray expression analysis of genes whose expression is correlated with tumorigenic and non-tumorigenic phenotype of HeLa X human fibroblast cells. Cancer Lett., 165, 210-209, 2001. 

Loy, A. Lehner, A. Lee, N. Adamczyk, J. Meier, H. Ernst, J. Schleifer, K.H. Wagner, M. Oligonucleotide microarray for 16S rRNA gene-based detection of all recognized lineages of sulfate-reducing prokaryotes in the environment. Appl. Environ. Microbiol. 2002, 68, 5064-5081. 

Levels of RNA (usually specific mRNAs) in a cell can be measured by well-established techniques such as Northern blot analysis or by polymerase chain reaction (PCR) analysis. However, the recent advent of DNA microarray technology has converted the identification and measurement of specific mRNAs (or other RNAs if required) into a high-throughput process. DNA arrays are also termed oligonucleotide arrays , gene chip arrays or simply, chips . 

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