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Ocular drug delivery therapeutics

Tammara, V. K. and M. A. Crider. 1996. Prodrugs A chemical approach to ocular drug delivery. Ocular therapeutics and drug delivery, edited by I. K. Reddy. Lancaster, Penn., USA. Technomic Publishing Company, pp. 285-334. [Pg.489]

These vesicular drug delivery systems can also carry a variety of molecules with therapeutic potential and offer different advantages for ocular drug delivery. In fact, several experiments have shown that liposome entrapped drugs have improved ocular bioavailability. ... [Pg.1195]

J. C. Lang and M. M. Stiemke, Biological barriers to ocular delivery in Ocular Therapeutics and Drug Delivery, A Multidisciplinary Approach (I. K. Reddy, ed.), Technomic Publishing Company, 1996, pp. 51-132. [Pg.475]

Topical instillation is the principal route of ophthalmic drug delivery in the horse. It is used in the treatment of adnexal diseases, such as blepharitis and mebomiaiutis, and diseases of the ocular surfaces, such as conjunctivitis, superficial keratitis and comeal ulceration. Depending upon their physicochemical formulation, some drugs traverse the intact conjimctival and comeal epithelial barrier. This results in therapeutic levels within the comeal stroma and anterior chamber, facilitating the topical treatment of comeal stromal... [Pg.218]

The Ocusert Pilo-20 and Pilo-40 Ocular Therapeutic System is an elliptical membrane that is soft and flexible and designed to be placed in the inferior cul-de-sac between the sclera and the eyelid and to release pilocarpine continuously at a steady rate for seven days. The design of the dosage form is described by Alza in terms of an open-looped therapeutic system, having three major components (i) the drug, (ii) a drug delivery module, and (iii) a platform. In the Ocusert Pilo-20 and Pilo-40 systems, the drug... [Pg.165]

Ocular pharmacology. 2. Drug delivery systems. 3. Therapeutics, Opthalmological. I. Jaffe, Glenn J. II. Ashton, Paul, 1960- III. Pearson, Andre, 1961-... [Pg.372]

PHARMACOKINETICS AND TOXICOLOGY OF OCULAR THERAPEUTIC AGENTS Drug Delivery Strategies... [Pg.1095]

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See also in sourсe #XX -- [ Pg.499 ]



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