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Drug entrapped in liposomes

Kirby C, Gregoriadis G. Dehydration-rehydration vesicles (DRV) a new method for high yield drug entrapment in liposomes. Biotechnology 1984 2 979-984. [Pg.244]

Drug entrapment in liposomes has been most extensively investigated, and evidence has been presented both in experimental animals and in humans that the drug residence time in the lung can be substantially extended [123— 129,131],... [Pg.98]

Karau, C., Pongpaibul, Y, and Schmidt, PC., Quantitative evaluation of human leukocyte interferon-entrapped in liposomes, Drug Delivery, 3, 59-62, 1996. [Pg.381]

Entrapment of drug substances in liposomes and micelles can lead to changes in their stability. When entrapment reduces the degradation rate, it can be used as a method for stabilizing pharmaceuticals. Aspirin can be partially stabilized by incorporation in L-a-dimyristoylphosphatidylcholine (DMPC)-based liposomes.489-491 Anesthetics such as procaine are also stabilized by incorporation in liposomes.490 Physostigmine salicylate in a phospholipid emulsion is stabilized through interaction with phospholipids at the oil-water interface and through incorporation into the internal phase of the emulsion (Fig. 131).549... [Pg.133]

Monitor the extent of drug entrapment in DRV liposomes by measuring the drug in the suspended pellet and combined supernatants. The easiest way to... [Pg.61]


See other pages where Drug entrapped in liposomes is mentioned: [Pg.328]    [Pg.554]    [Pg.412]    [Pg.467]    [Pg.467]    [Pg.353]    [Pg.328]    [Pg.554]    [Pg.412]    [Pg.467]    [Pg.467]    [Pg.353]    [Pg.297]    [Pg.555]    [Pg.862]    [Pg.442]    [Pg.156]    [Pg.219]    [Pg.284]    [Pg.442]    [Pg.140]    [Pg.175]    [Pg.474]    [Pg.1165]    [Pg.4127]    [Pg.195]    [Pg.8]    [Pg.81]    [Pg.88]    [Pg.570]    [Pg.355]    [Pg.807]    [Pg.133]    [Pg.66]    [Pg.284]    [Pg.195]    [Pg.807]    [Pg.277]    [Pg.310]    [Pg.403]    [Pg.383]    [Pg.492]    [Pg.59]    [Pg.60]    [Pg.224]    [Pg.277]   
See also in sourсe #XX -- [ Pg.219 , Pg.222 ]




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