2- O-Cresyl

Boskovic, B. (1978). The influence of 2-(o-cresyl)-4 H-l 3 2 benzodioxa-phosphorin-2-oxide (CBDP) on organophosphate poisoning and its therapy. Arch. Toxicol. 42 207-16. 

The specific CarbE inhibitors tri-ort/io-cresyl-phosphate (TOCP) (Mendel and Myers, 1953) and 2-[o-cresyl]-4H-l,2,3-benzodioxa-phosphorin-2-oxide (CBDP) (Casida... 

McKay, D.H., Jardine, R.V., Adie, P.A. (1971). The synergistic action of 2-(o-cresyl)-4H-l 3 2-benzodioxaphosphorin-2-oxide with soman and physostigmine. Toxicol. Appl. Pharmacol. 20 474-9. 

FIGURE 24.4 Master curves of the local segmental relaxation times for 1,4-polyisoprene (-y = 3.0) 1,2-polybutadiene (7=1.9) polyvinylmethylether (7 = 2.55) polyvinylacetate (7 = 2.6) polypropylene glycol (7 = 2.5) polyoxybutylene (7 = 2.8) poly(phenyl glycidyl ether)-co-formaldehyde (7 = 3.5) polymethylphe-nylsiloxane (7 = 5.6) poly[(o-cresyl glycidyl ether)-co-formaldehyde] (7 = 3.3) and polymethyltolylsiloxane (PMTS) (7 = 5.0) [15 and references therein]. Each symbol for a given material represents a different condition of T and P. 

For definition of k3 see equation 2 substrates used o-cresyl /3-D-gluco-pyranoside and o-cresyl /3-n-galactopyranoside. 

Synonyms AI3-00137 BRN 0506917 CCRIS 646 2-Cresol o-Cresol o-Cresylic acid EINECS 202-423-8 FEMA No. 3480 l-Hydroxy-2-methylbenzene 2-Hydroxytoluene o-Hydroxytoluene 2-Methylhydroxybenzene o-Methylhydroxybenzene o-Methylphenol o-Methylphenylol NSC 23076 Orthocresol o-Oxytoluene RCRA waste number U052 2-Toluol o-Toluol UN 2076. 

Synonyms AI3-00520 BRN 1892885 CCRIS 6421 o-Cresyl phosphate EINECS 201-103-5 Fyrquel 150 NSC 438 Phosflex 179-C Phosphoric acid, tris(2-methylphenyl) ester Phosphoric acid, tri-2-tolyl ester Phosphoric acid, tri-o-cresyl ester o-TCP TCP TOCP TOFK o Tolyl phosphate TOTP Tricresyl phosphate Triorthocresyl phosphate Tri-2-methylphenyl phosphate Tris(o-cresyl)phosphate Tris(o-methylphenyl)phosphate Tris(o-tolyl)phosphate Tri-2-tolyl phosphate Tri-o-tolyl phosphate. 

Benzyl butyl phthalate Benzo [ 6] fluoranthene Benzo [A] fluoranthene Benzol a] pyrene Benzo lei pyrene Tri-o-cresyl phosphate Strychnine Benzo ghi pery lene Indenoll,2,3-crfl pyrene Dibenzo la, A1 anthracene Bis(2-ethylhexyl) phthalate Di-n-octyl phthalate Ammonia... 

Phosphoric acid, triphenyl ester, see Triphenyl phosphate Phosphoric acid, tris(2-methylphenyl) ester, see Tri-o-cresyl phosphate... 

TNT, see 2,4,6-Trinitrotoluene a-TNT, see 2,4,6-Trinitrotoluene TNT-tolite, see 2,4,6-Trinitrotoluene TOCP, see Tri-o-cresyl phosphate TOFK, see Tri-o-cresyl phosphate Tolit, see 2,4,6-Trinitrotoluene Tolite, see 2,4,6-Trinitrotoluene... 

Trimethylnorcamphor, see Camphor Trimethylphenylmethane, see ferf-Butylbenzene Tri-2-methylphenyl phosphate, see Tri-o-cresyl phosphate 1,1,1-Trimethylpropane, see 2,2-Dimethylbutane... 

Vora DD TdxIc polyneuritis in Bombay due to ort o-cresyl-phosphate poisoning. 7 A/e ro/ Neurosurg Psychiatry 25 23 2 2, 1962... 

The alcoholysis of sulfites such as dimethyl sulfite offers a convenient method for the preparation of high-boiling dialkyl sulfites [33]. Earlier, Voos and Blanke [8a] reported that dimethyl sulfite is converted to diethyl sulfite in 44 % yield. The reaction was shown to be acid-catalyzed and failed when barium carbonate was present. However, a patent refers to the use of lithium hydride in the transalcoholysis of 2,2-(4,4 -dihydroxyphenyl)propane with diphenyl sulfite or di-o-cresyl sulfite [32]. Recently Mehrotra and Mathur [34] reported that the alcoholysis reaction proceeds in the absence of catalysts. Their results are summarized in Eqs. (21)—(23) and Table VII. Tertiary butanol did not... 

An example of absolutely cumulative toxicity is afforded by tri-o-cresyl phosphate or TOCP (Fig. 2.13). This compound is a cholinesterase inhibitor and neurotoxin. In chickens, an acute dose of 30 mg /kg has a severe toxic effect, which is produced to the same extent by a dose of 1 (mg/kg)/day given for 30 days. This effect may of course be produced by accumulation of the compound in vivo to a threshold toxic level, or it may result from the accumulation of the effect, as it probably does in the case of TOCP. 

The toxic effects of tri-o-cresyl phosphate are cumulative such that a dose of 1 mg kg-1 day-1 for 30 days will give the same toxic effects as a single dose of 30 mg kg-1. See text in Chapter 2 for further details and a full explanation. 

FIGURE 57.3. Examples of delayed neuropathic (DN) agents containing pentavalent phosphorus ethyl n-octylphosphono-fluoridate (EOPF) and 2-(2-methylphenoxy)-4iT-l,3,2-benzodiox-aphosphorin-2-oxide [2-(2-methylphenoxy)-BDPO], the active metabolite of the archetypal DN agent, tri-o-cresyl phosphate (TOCP) (Wu and Casida, 1995). 

SYNS 2-CRESOL o-CRESYLIC ACID 1-HYDROXY-2-METHYLBENZENE o-HYDROXYTOLUENE o-KRESOL (GERMAN) o-METHYLPHENOL 2-METHYLPHENOL ORTHOCRESOL o-OXYTOLUENE ORCRA WASTE NUMBER U052 o-TOLUOL... 

SYNS o-CRESYL PHOSPHATE PHOSFLEX 179-C PHOSPHORIC ACID, TRI-o-CRESYL ESTER PHOSPHORIC ACID, TRIS(2-METHYLPHENYL) ESTER TOCP TOFK o-TOLYL PHOSPH.ATE TOTP TRICRESAT. PHOSPHATE TRI-o-CRESYL PHOSPHATE... 

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