3 ,4 -Dihydroxyphenyl-3- propan

The alcoholysis of sulfites such as dimethyl sulfite offers a convenient method for the preparation of high-boiling dialkyl sulfites [33]. Earlier, Voos and Blanke [8a] reported that dimethyl sulfite is converted to diethyl sulfite in 44 % yield. The reaction was shown to be acid-catalyzed and failed when barium carbonate was present. However, a patent refers to the use of lithium hydride in the transalcoholysis of 2,2-(4,4 -dihydroxyphenyl)propane with diphenyl sulfite or di-o-cresyl sulfite [32]. Recently Mehrotra and Mathur [34] reported that the alcoholysis reaction proceeds in the absence of catalysts. Their results are summarized in Eqs. (21)—(23) and Table VII. Tertiary butanol did not... 

Amino-l-(3,4-dihydroxyphenyl)propane, A4.9 Methyl 8-methyl-8-azabicyclo[3.2.l]oct-2-ene-3-carboxylate, K"9.5 C10H15N2OPS... 

Curtis, R.F., P.C. Harries, and C.H. Hassal The Synthesis of (2-Carboxy-3,5-dihydroxyphenyl)propan-2-one (C-Acetyl-c7-orsellinic Acid). J. Chem. Soc. (London) 1964, 5382. 

The resulting solution was filtered through animal charcoal and, after addition of 2 liters of methanol, it was debenzylated by hydrogenation at 60°C over palladinized charcoal as a catalyst. After removal of the catalyst by filtration, the filtrate was concentrated by evaporation, whereupon the hydrochloride of 1-p-methoxyphenyl-2-((3-3, 5 -dihydroxyphenyl-(3-oxo)-ethylamino-propane (MP 244°C) crystaiiized out. For the purpose of demethyiation. 

A Garzon, A Poupaert, M Claesen, P Dumont. A lymphotropic prodrug of L-dopa Synthesis, pharmacological properties, and pharmacokinetic behavior of 1,3-dihex-adecanoyl-2-r(S)-2-amino-3-(3,4-dihydroxyphenyl) propanoyl] propane-1,2,3-triol. J Med Chem 29 687-691, 1986. 

N-Acetyldopamine A -[2-(3,4-dihydroxyphenyl)ethyl]-acetamide and N-P-alanyldopamine (3-amino-A -[2-(3,4-dihydroxyphenyl)ethyl]propanamide) occur in insects where they serve to form the sclerotized cuticle required for the exoskeleton. They are transformed by enzymatic oxidation to the corresponding o-quinones and p-quinonemethides which cross-link structural proteins with each other and with chitin. The biosynthesis of N-acetyldopamine starts from dopamine and acetyl-CoA by way of arylamine-A acyltransferase (EC 2.3.1.5). In contrast to the biosynthesis of (/f)- noradrenaline, the p-quinonemethides, generated non-selectively by enzymatic oxidation from N-ace-tyldopamine or )V-)3-alanyldopamine, undergo addition of water to furnish the racemic side-chain hydrox-ylated derivatives N-acetylnoradrenaline ()V-[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]acetamide) or, respectively N- alanylnoradrenaline (3-amino-)V-[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]propan-amide). 

Treatment of the fisetinidol-(4a—>8)-catechin (24) (57), representing a typical tannin unit of commercial wattle extract, with sodium cyanoborohydride [Na(CN)BH3] 84) in trifluoroacetic acid (TFA) for 6h at 0°C gave products comprising the starting material (24), catechin (5) (15%) and the (2jR)-l-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphe-nyl)propan-2-ol (77) (Scheme 6). Similar treatment of the fisetinidol-(4P- 8)- and -(4a- 6)-catechins (69) and (71) (57) with their respective... 

Nesterov, A., Zhao, J., Minter, D., Heitel, C., Ma, W., Abeysinghe, R, Hong, M., Jia, Q. (2008) l-(2,4-dihydroxyphenyl)-3-(2,4-dime-thoxy-3-methyl-phenyl)propane, a novel tyrosinase inhibitor with strong depigmenting effects. Chem Pharm Bull, 56 (9) 1292-1296. 

M-00065 Mercaptobutanedioic acid ( )- 22583-30-8 Propanal (3-phenyl-2-quinoxalinyl) hydrazone, P-00260 22919-59-1 1 -(2,4-Dihydroxyphenyl)-1 -butanone Oxime, in D-00707... 

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