Nitric oxide crystal structure

Alcohol. Traube Reaction. The Traube reaction (23, 28, 29) involves the conversion of ethyl alcohol, in the presence of added base, to methylenediisonitra-mine by nitric oxide. The structure of the product has been established by a single-crystal x-ray study. 

Fedorov, R., D.K. Ghosh, and 1. Schlichting (2003). Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase—structural models of the short-lived oxygen complexes. Arch. Biochem. Biophys. 409, 25-31. 

Structure 20 and salts 115 and 116 are formed by condensation of nitric oxide with diethylmalonate. Arulsamy and Bohle warn that this new type of compact ring structure forms dense crystals, and compounds 20, 115, and 116 are potential energetic materials which decompose violently at high temperatures <2002AGE2089>. 

Manganese nitrosyl porphyrins [215] are considered good models for the iron-nitric oxide analogs, which are relatively unstable but very vital to many biological operations. A six-coordinate manganese nitrosyl porphyrin of the form (por)Mn(NO)(L), where por can be TTP (TTP = tetra(4-methylphenyl)porphine) and L = piperidine, methanol, 1-methyhmidazole, has been prepared [216] in moderate yields by the reductive nitrosylation of the (por)MnCl complex with NO in piperidine. The crystal structures of these compounds give indication of a linear Mn-NO bond [215]. 

Li, H., Raman, C. S., Glaser, C. B., Blasko, E., Young,T. A., Parkinson, J. F., Whitlow, M., Poulos. T. L., Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase, ]. Biol.Chem. 

In summary, there is still much to understand about the nitrite reduction reaction. The crystal structures have shown how nitrite can bind to the di heme iron and protons can be provided to one of its oxygen atoms from two histidine residues. However, as yet no rapid reaction study has detected the release of product nitric oxide rather than the formation of the inhibitory dead-end ferrous di heme-NO complex. It is also not clear why the rate of interheme electron transfer is so slow over 11 A when nitrite or nitric oxide is the ligand to the d heme. 

The oxide exhibits two crystalline modifications, the reddish or orange-red alpha form, known as litharge, and the yellow beta form, massicot. The alpha form constitutes tetragonal crystals while the beta modification is a yellow amorphous powder of orthorhombic crystal structure. The alpha form is stable at ordinary temperatures, converting to the beta form when heated at 489°C density 9.35 g/cm (beta form) Moh s hardness 2 (alpha form) the oxide melts at 888°C vaporizes at 1,472°C with decomposition vapor pressure 1 torr at 943° C and 5 torr at 1,039°C practically insoluble in water (the solubdity of alpha form is 17 mg/L at 20°C and that of beta form 23 mg/L at 22°C) insoluble in ethanol soluble in dilute nitric acid and aUtahes. 

The double nitrates Mg3M2(N03)12, 24 H20 can be recrystallized in strong nitric acid and serve to separate the lighter lanthanides M = La, Pr, Nd and Sm (where Ce has been removed after oxidation to the quadrivalent state). Judd noted 109) that the fine-structure of the absorption band belonging to each /-level of M(III) was so peculiar that it looked as if the chromophore was icosahedral with N = 12 (which is almost unheard about, outside boron chemistry). The crystal structure 110) of the cubic crystals confirmed entirely Judd s proposal, it is indeed [Mg(OH2)6]3 ... 

Raman, C.S., Li, H., Martasek, P., Southan, G., Masters, B. S. S., Poulos, and Thomas, L. (2001), Crystal Structure of Nitric Oxide Synthase Bound to Nitro Indazole Reveals a Novel Inactivation Mechanism, Biochemistry 40 13448-13455. 

Wilmot et al. (1999) have reported high resolution crystal structures of three species relevant to understanding the chemistry of the oxidative half cycle of amine oxidases, (i) anaerobic substrate-reduced ECAO, (ii) anaerobic substrate-reduced ECAO with bound nitric oxide (an oxygen mimic) and (iii) ECAO reacted aerobically with substrate to reach an equilibrium turnover state, then cryo-trapped. In all these species, product aldehyde remains bound at the back of the substrate binding pocket and this seems to be crucial in allowing build up of intermediates. 

Edwards, S. L., Kraut, J., and Poulos, T. L., 1988, Crystal structure of nitric oxide inhibited cytochrome c peroxidase. Biochemistry 27 8074n8081. 

Raman CS, Li H, Martasek P, Krai V, Masters BS, Poulos TL. Crystal structure of constitutive endothelial nitric oxide synthase a paradigm for pterin function involving a novel metal center. Cell 1998 95 939-950. 

The product isolated from the reaction of [RhCl(S02)(PR3)2] R = Cy, n-butyl ("Bu), tso-propyl ( Pr) with gaseous nitric oxide has proved difficult to characterize uniquely (68). Analytical data suggested the formulation [RhCl(NO)2(PR3)2] and the IR spectrum gave two stretching frequencies at 1638 and 1664 cm consistent with structure (10), which contains two bent nitrosyl groups. The crystal structures of both the tri-n-butylphosphine and tricyclohexylphosphine derivatives con-... 

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