Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Nicotinic receptors subtypes

The nicotinic acetylcholine (nACh) receptor also displays sensitivity to inhalants (Bale et al. 2002). To varying degrees, toluene appeared to antagonize the function of nACh receptors that comprise different subunits. At concentrations of 50 pM to 10 mM, toluene produced a reversible, concentration-dependent inhibition of acetylcholine-induced current in Xenopus oocytes expressing various nicotinic receptor subtypes, with the ol — 2 d ct3—P2 subunit combinations being more sensitive to inhibition than other receptor... [Pg.284]

Vailati, S., Moretti, M., Balestra, B., McIntosh, M., Clementi, F., Gotti, C. Beta3 subunit is present in different nicotinic receptor subtypes in chick retina. Eur. J. Pharmacol. 393 23, 2000. [Pg.32]

Clarke PB, Reuben M. (1996). Release of [3FI]-noradrenaline from rat hippocampal synaptosomes by nicotine mediation by different nicotinic receptor subtypes from striatal [3FI]-dopamine release. BrJ Pharmacol. 117(4) 595-606. [Pg.448]

Mogg AJ, Jones FA, PuUar lA, Sharpies CG, Wonnacott S (2004) Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380. Neuropharmacology 47 848-859... [Pg.202]

Nuutinen S, Barik J, Jones IW, Wonnacott S (2007) Differential effects of acute and chronic nicotine on Elk-1 in rat hippocampus. Neuroreport 18 121-126 Olale E, Gerzanich V, Kuryatov A, Wang E, Lindstrom J (1997) Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes. J Pharmacol Exp Ther 283 675-683... [Pg.203]

Xiao Y, KeUar KJ (2004) The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammahan cells. 1 Pharmacol Exp Ther 10 98-107... [Pg.208]

So, parasympathetic nerves use acetylcholine as a neurotransmitter and cholinomimetic drugs mimic the action of acetylcholine at its receptors. Muscarinic receptor subtypes are found on neuroeffector junctions. Nicotinic receptor subtypes are found on ganglionic synapses. Chohnomimetics can be classified as ... [Pg.180]

It is speculated that both nicotine and mecamylamine may act via prolonged inactivation of acetylchol-inergic nicotinic-receptor subtypes (Young et al., 2001). In the absence of larger series or controlled doubleblind studies, however, the effectiveness of nicotinergic agents in augmenting neuroleptic treatment of tics remains unclear. [Pg.533]

Marutle A, Zhang X, Court J, Piggot M, Johnson M, et al. 2001. Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. J Chem Neuroanat 22 115-126. [Pg.34]

Tribollet E, Bertrand D, Marquerat A, Raggenbass M. 2004. Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging An autoradiographic study in the rat brain. Neuroscience 124 405-420. [Pg.37]

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. J Chem Neuroanat 22 115-126. [Pg.485]

Sher E, Chen Y, Sharpies TJ, Broad LM, Benedetti G, et al. 2004. Physiological roles of neuronal nicotinic receptor subtypes New insights on the nicotinic modulation of neurotransmitter release, synaptic transmission and plasticity. Curr Top Med Chem 4 283-297. [Pg.489]

Phillips JM, Ehrlichman RS, Siegel SJ. 2006. Nicotine receptor subtype contributions to the beneficial and detrimental effects of nicotine on event related potentials. Society for... [Pg.542]

Diazabicyclo[2.2.1]heptane derivatives, (n) and (III), prepared by Miller (6) and Lochead (7), respectively, were effective as nicotinic receptor subtypes agonists and used in the treatment of central nervous systems disorders. [Pg.82]

McClure-Begley TD, King NM, CoUins AC, Stitzel JA, Wehner JM, Butt CM (2009) Acetylcholine-stimulated [3H]GABA release from mouse brain synaptosomes is modulated by alpha4beta2 and alpha4alpha5beta2 nicotinic receptor subtypes. Mol Pharmacol 75 918-926... [Pg.778]

Quik M, Sum JD, Whiteaker P, McCaUum SE, Marks MJ, Musachio J, McIntosh JM, Collins AC, Grady SR (2003) Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice. Mol Pharmacol 63 1169-1179... [Pg.780]

Zoli M, Moretti M, Zanardi A, McIntosh JM, Clementi F, Gotti C (2002) Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. J Neurosci 22 8785-8789... [Pg.784]

The acute toxicity (i.e., lethal potency) of imidacloprid, other neonicotinoids, and related analogs in mammals is most closely related to potency at the 7 nicotinic receptor subtype, followed in order by potency at 1x4, fSx, 0(3, and aj nicotinic receptors, respectively. However, acute toxicity in mammals involves complex actions (agonist and antagonist) at multiple receptor subtypes and these actions vary greatly with minor changes in chemical structure. [Pg.1379]

The recommended treatment in cases of acute poisoning is symptomatic. It is important to monitor and support breathing if signs of respiratory paralysis appear and to monitor blood pressure and pulse rate, since bradycardia and hypotonia may occur. Since imidacloprid does not inhibit acetylcholinesterase activity, treatment with a reactivating oxime (e.g., pralidoxime) is not indicated. Furthermore, treatment with a nicotinic antagonist may be ineffective or potentially harmful since symptoms of poisoning may be mediated by stimulation or inhibition of various nicotinic receptor subtypes or by other possible mechanisms. [Pg.1381]

Zwart R, Oortgiesen M, and Vijverberg HPM (1992) The nitromethylene heterocycle l-(pyridin-3-yl-methyl)-2-nitromethylene-imidazolidine distinguishes mammalian from insect nicotinic receptor subtypes. European Journal of Pharmacology 228 165-169. [Pg.1381]

Qualitatively, choline has the same pharmacological actions as acetylcholine, but it is far less active at most sites (58). However, choline has been reported (34) to be a full agonist at one nicotinic receptor subtype, and at some other nicotinic subtypes it can act as a partial agonist or a coagonist. [Pg.45]

See other pages where Nicotinic receptors subtypes is mentioned: [Pg.23]    [Pg.228]    [Pg.125]    [Pg.110]    [Pg.112]    [Pg.169]    [Pg.200]    [Pg.205]    [Pg.208]    [Pg.295]    [Pg.298]    [Pg.309]    [Pg.322]    [Pg.269]    [Pg.303]    [Pg.561]    [Pg.563]    [Pg.403]    [Pg.779]    [Pg.779]    [Pg.779]    [Pg.550]    [Pg.550]    [Pg.129]    [Pg.198]    [Pg.42]    [Pg.807]    [Pg.885]   
See also in sourсe #XX -- [ Pg.298 , Pg.309 , Pg.322 ]



SEARCH



Nicotinic acetylcholine receptor subtypes

Nicotinic receptors

Receptor Subtype

Subtype

Subtypes

Subtyping

© 2024 chempedia.info