New Sampling and Sensor Initiative

Dr. David Veltkamp of CPAC describes in Chapter 10 the developments and present status of NeSSI (New Sampling and Sensor Initiative) and how it could enhance the use of microsystems. This initiative has progressed from primarily a standard for process sampling to a potential base for studies involving microreactors and analytical tools. 

It is envisioned that many of these technologies will ultimately be compatible with the NeSSI (New Sampling and Sensor Initiative) platform and, thus, will be added to the growing toolbox of characterization technologies that could be used in an array format for the generahon of meaningful data. The technologies described include ... 

D.J. Veltkamp, New platform for sampling and sensor initiative (NeSSI), in Micro Instrumentation for High Throughput Experimentation and Process Intensification - a Tool for PAT, M.V. Koch, K. M. VandenBussche and R.W. Chrisman (eds), Wiley-VCH, Weinheim, 2007. 

NEW SAMPLING AND SENSOR INITIA TIVE (NeSSI) CHEMOMETRICS ON-LINE INITIATIVE... 

The New Sampling an Sensor Initiative (NeSSI) platform for demonstrating and deployment of micro-analytical devices... 

In any case, the size constraints for this DARPA commissioned research far exceed those of NeSSI s (New Sampling and Sensing Initiative) modular and standardized micro-analytic elements, so that these sensors will easily fit on a NeSSl substrate for even further application possibilities. The drastic reduction in size, analysis time, cost, and energy consumption, ease of implementation and maintenance, and compliance with NeSSl standards make this technology highly marketable to the civilian sector. 

As stated by Manz, the pTAS was envisioned as a new concept for chemical sensing, needed since sensors at that time were not providing the best results in terms of selectivity and lifetime. Initially, the main reason for miniaturisation was to enhance the analytical performance of the device rather than to reduce its size. However, it was also recognised that a small scale presented the advantage of a smaller consumption of sample and reagents. Moreover, the total chemical analysis system scheme could provide an integration of several laboratory procedures such as sample preparation, filtration, preconcentration,... 

The American consortium NeSSI [23] (New Sampling Sensor Initiative) is a CPAC-sponsored (Center for Process Analytical Chemistry) open initiative formed in 2000 to create a standard for process analysis. The object is to implement modular and smart process analytics. It also aims at the future integration of micro analytical devices and micro structured reactors. The concept is derived from the semiconductor industry and follows the ISA SP76 standard. Companies such as Parker-Hannifin, Kinetics and Swagelok are involved. Further information is also given on the web site [23],... 

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