Nervous system neuron

Zakany, J., Tuggle, C. K., Patel, M. D and Nguyen-Huu, C. M. (1988). Spatial regulation of homeobox gene fusions in the embryonic central nervous system. Neuron 1 679-691. 

Hatten ME 1999 Central nervous system neuronal migration. Annu Rev Neurosci 22 511—539 Horstadius S 1973 Experimental embryology of echinoderms. Clarendon Press, Oxford Horvitz HR, Herskowitz 11992 Mechanisms of asymmetric cell division two Bs or not two Bs, that is the question. Cell 68 237-255... 

Hayashi, H., Campenot, R. B., Vance, D. E. and Vance, J. E. Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures. J. Biol. Chem. 279 14009-14015,2004. 

Peters, A., Palay, S. L. and Webster, H. D. The Fine Structure of the Nervous System Neurons and their supporting cells., 3rd edn. New York Oxford University Press, 1991. 

Brady, S. T. Molecular motors in the nervous system. Neuron 7 521-533,1991. 

Binds to DNA and prevents separation of the helical strands Affects neuronal transmissions Binds to opiate receptors and blocks pain pathway Acts as central nervous system depressant Inhibits Na/K/ATPase, increases intracellular calcium, and increases ventricular contractibility Blocks the actions of histamine on Hi receptor Blocks ai-adrenergic receptor, resulting in decreased blood pressure Inhibits reuptake of 5-hydroxytryptamine (serotonin) into central nervous system neurons Inhibits cyclooxygenase, inhibition of inflammatory mediators Inhibits replication of viruses or tumor cells Inhibits HIV reverse transcriptase and DNA polymerase Antagonizes histamine effects... 

Histamine (2-[4-imidazole] ethylamine) is a low-molecular-weight amine synthesized from L-histidine exclusively by histidine decarboxylase. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes [1-4]. Since its discovery as a uterine... 

Fisher TE, Carrion-Vazquez M, Oberhauser AF, Li H, Marszalek PE, Fernandez JM. Single molecule force spectroscopy of modular proteins in the nervous system. Neuron 2000 27 435-446. 

Frisch B, Hardin PE, Hamblen-Coyle MJ, Rosbash M, Hall JC 1994 A promoterless DNA fragment from the period locus rescues behavioral rhythmicity and mediates cyclical gene expression in a restricted subset of the Drosophila nervous system. Neuron 12 555—570 Glossop NR, Houl JH, Zheng H, Ng FS, Dudek SM, Hardin PE 2003 VRILLE feeds back to control circadian transcription of clock in the Drosophila circadian oscillator. Neuron 37 249-261... 

The AChR in muscle is distinct from the AChRs found in the central and autonomic nervous systems (neuronal AChRs). Although both are activated by nicotine, each is blocked by a different antagonist (e.g., a-BTX vs. k-BTX). 

Trapp T, Rupprecht R, Castren M, et al Heterodimerization between mineralocorticoid and glucocorticoid receptor a new principle of glucocorticoid action in the central nervous system. Neuron 13 1-6, 1994... 

Nicotinic receptors are part of a transmembrane polypeptide whose subunits form cation-selective ion channels (see Figure 2-9). These receptors are located on plasma membranes of postganglionic cells in all autonomic ganglia, of muscles innervated by somatic motor fibers, and of some central nervous system neurons (see Figure 6-1). 

Usuda, N., Arai, H., Sasaki, H., Hanai, T., Nagat, T., Muramatsu, T., Kincaid, R. L., and Higuchi, S. 1996. Differential subcellular localization of neural isoforms of the catalytic subunit of calmodulin dependent protein phosphatase (calcineurin) in central nervous system neurons Immunohistochemistry on formalin-fixed paraffin sections employing antigen retrieval by microwave irradiation. J. Histochem. Cytochem. 44 13-18. 

Choi D. W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron 1 628-634. 

Lonze, B. E. and Ginty, D. D., 2002, Function and regulation of CREB family transcription factors in the nervous system, Neuron, 35, pp 605-23. 

Huguenard JR (1996) Fow-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 58 329-348. 

Muscle-derived differentiation factor (MDF) induces tyrosine hydroxylase expression in a variety of central nervous system neurons, including those of striatum, cerebellum, and cortex. Normally, i.e., without MDF, these neurons do not express this enzyme of catecholamine synthesis. Further in vitro studies revealed that MDF enhances TH-mRNA 40-fold in fetal mesencephalic neurons. In vivo studies, employing infusion of partially isolated MDF, reported this molecule to enhance tyrosine hydroxylase activity in dopamine-depleted striata of 6-OHDA-lesioned animals. Furthermore, an increase of striatal dopamine concentrations and a partial compensation of rotational asymmetry were observed. In contrast, dopaminergic parameters were not affected by administration of MDF in control animals, suggesting that adult dopaminergic neurons may regain sensitivity toward differentiation factors after lesion. 

NEURONS Nerve cells found throughout the central nervous system. Neurons release neurotransmitters. 

As suggested in Chapter 6 Introduction to Autonomic Pharmacology, the Mi receptor subtype appears to be located on central nervous system neurons, sympathetic postganglionic cell bodies, and many presynaptic sites. M2 receptors are located in the myocardium, smooth muscle organs, and some neuronal sites. M3 receptors are most common on effector cell membranes, especially glandular and smooth muscle cells. 

Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA 1993 90(17) 7951-7955. 

Choi, D. W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634. Choi, D. W. (1990). Methods for antagonizing glutamate neurotoxicity. Cerebrovasc. BrainMetab. Rev. 2, 105-147. 

Ye JH, Hunt T, Wu WH, McArdle JJ. Ondansetron modulates GABA(A) current of rat central nervous system neurons. Eur J Pharmacol 1997 337 87-94. 

Noble M, Fok-Seang J, Cohen J (1984) Glia are a unique substrate for the in vitro growth of central nervous system neurons. J Neurosci 4 1892-1903. 

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