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Natural killer cell assay

Natural Killer Cell Assays. This assay is a Tier I test for nonspecific immunity in the NTP testing scheme (Luster et al., 1988) and is proposed as an additional Type I test in the draft Redbook. [Pg.568]

NATURAL KILLER CELL ASSAY AND OTHER INNATE IMMUNITY TESTS... [Pg.78]

Chapter 3.1.2 Natural Killer Cell Assay and Other Innate Immunity Tests... [Pg.417]

Finally, multiparameter flow cytometry has the potential to improve existing methodologies for the evaluation of immunotoxicological endpoints such as the natural killer cell (NK) assay and the local lymph node assay (LLNA) to evaluate innate immunity and chemical-induced allergic disease. Accepted methodologies typically utilize radio-... [Pg.118]

Several cytokines have been characterized at the molecular level in different species of marine mammals (Table 23.2). In addition, limited evidence exists for conserved functionality of cytokines in marine mammals, such as the ability of human recombinant IL-2 to stimulate T cell proliferation [32, 33] and natural killer cell activity [39,40] in beluga whales and harbor seals. Assays were developed to quantify circulating levels of cytokines [41,42], as well as C-reactive protein, a marker of acute inflammation [43],... [Pg.409]

Riccardi, C., Puccetti, P., Santoni, A. and Herberman, R.B. (1979). Rapid in vivo assay of mouse natural killer cell activity. J. Natl. Cancer Inst. 63 1041-1045. [Pg.593]

The most relevant bioassays measure specific activities on immune function, either as effector or regulatory, for example, assay of cytokine IL-12 by the augmentation of the cytolytic function of natural killer cells (B9), IL-10 by the inhibition of the production of TNF-o from stimulated monocytes (B13), and IL-8 and eotaxin by the chemotaxis of neutrophils and eosinophils, respectively (C2). [Pg.21]

Blom WMW, van Nielen WGLW, de Groene EME, Albers RR (2009) A cell-based screening assay for Natural Killer cell activity. Int Immunopharmacol 9 746-752... [Pg.265]

Johann S, Bltlmel G, Lipp M, Forster R. A versatile flow-cytometry-based assay for the determination of short- and long-term natural killer cell activity. J Immunol Methods 1995 185 209-216. [Pg.85]

Blomberg, K., Granberg, C., Hemmila, I., and Lbvgren, T. (1986) Europium-labelled target cells in an assay of natural killer cell activity. I. A novel non-radioactive method based on time-resolved fluorescence. J. Immunol. Meth. 86 225-229. [Pg.99]

In vitro assays of activity of natural killer cells Mitogenic stimulation assay of B- and T-lymphocytes Macrophage activity assays Stem cell assays... [Pg.87]

Cholujova, D. Jakubikova, J. Kubes, M. Arendacka, B. Sapak, M. Robert, L Sedlak, J. Comparative study of four fluorescent probes for evaluation of natural killer cell cytotoxicity assays. Immunobiology 2008, 213, 629-640. [Pg.76]

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See also in sourсe #XX -- [ Pg.77 , Pg.285 ]



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