Mycotoxins zearalenone

Jemmali M, Ueno Y, Ishii K, Frayssinet C, Etienne M (1978) Natural occurrence of trichothecenes, nivalenol, deoxynivalenol, T-2 toxin and zearalenone in corn. Experientia 34 1333-1334 Josephs RD, Schuhmacher R, Krska R (2001) International interlaboratory study for the determination of the Fusarium mycotoxins zearalenone and deoxynivalenol in agricultural commodities. Food Addit Contam 18 417-430... 

Josephs RD, Krska R, MacDonald S, Wilson P, Pettersson H (2003) Preparation of a calibrant as certified reference material for determination of thc fusarium mycotoxin zearalenone. J AOAC Int 86 50-60... 

Kuiper-Goodman T, Scott PM, Watanabe H (1987) Risk assessment of the mycotoxin zearalenone. Regul Toxicol Pharmacol 7 253-306... 

Malekinejad H, Schoevers EJ, Daemen IJ, Zijlstra C, Colenbrander B, Fink-Gremmels F, Roelen BAJ (2007) Exposure of oocytes to the Fusarium toxins zearalenone and deoxynivalenol causes aneuploidy and abnormal embryo development in pigs. Biol Reprod 77 840-847 Maragos CM, Appell MD (2007) Capillary electrophoresis of the mycotoxin zearalenone using cyclodextrin-enhanced fluorescence. J Chromatogr A 1143 252-257... 

Disbold et al. [34] developed a laser fluorimetric method for the determination of zearalenone (6-(10-hydroxy-6-oxo-fra s-l-undcccnyl-/i-resorcylic acid n-lactone))-infected corn. By combining laser fluorimetry with high-pressure liquid chromatography, these workers were able to detect and quantitate the naturally fluorescent mycotoxin zearalenone in contaminated corn samples. 

McCooeye, M. Kolakowski, B. Boison, J. Mester, Z., Evalnation of high-field asymmetric waveform ion mobility spectrometry mass spectrometry for the analysis of the mycotoxin zearalenone, A aZ. Chim. Acta 2008, 627, 112-116. 

According to their structural diversity, the RALs exhibit a variety of biological activities. Although it is classed as a mycotoxin, zearalenone (479) is barely toxic (9). Its anabolic and uterotrophic traits 338) are the result of its interaction with estrogenic receptors. Zearalenone (479) is able to bind to these receptors and thus mimic the ability of 17 S-estradiol to stimulate transcriptional activity. Therefore, it... 

Animals that consume moldy feeds excrete the estrogenic polyketide mycotoxins zearalenone (51) and zearalenol (52) in milk and milk products (Fig. 5,24). The same compound sometimes is found in beer. Zearalenol and zearalenone are synthesized by Fusarium species these compounds produce sterility and other reproductive problems in livestock (Beier and Nigg, 1992). 

Boeira, L., Bryce, J., Stewart, G., Flannigan, B. (2002). Influence of cultural conditions on sensitivity of brewing yeasts growth to Fusarium mycotoxins zearalenone, deoxynivalenol and fumonisin Bl. International Biodeterioration and Biodegradation, 50, 69-81. 

Biomolecules labeled with (aUcyne)[Co2(CO)g] entities are among the most widely studied molecules in bioorganometallic chemistry, thanks to their ease of preparation and reasonable stabiUty [96], It is thus no surprise that the Uterature provides examples of peptides [97, 98], proteins [99], therapeutic drugs [100], abortifacient medications such as RU486, 35 [101], corticoids and androgens [102], methotrexate 37 [103], the mycotoxin zearalenone 36 [104, 105], estrogens [106-110] and pesticides [111] modified by this entity (Scheme 3.15). 

Gas Chromatographic Detection of the Mycotoxin Zearalenone in Blood Serum... 

Hitchcock, S.A. and Pattenden, G. (1992) Total Synthesis of the Mycotoxin (-)-Zearalenone Based on Macrocyclization using a Cinnamyl Radical Intermediate, J. Chem. Soc., Perkin Trans. 1, 1323-1328. 

In the mycotoxine zearalenone a cis and a trans form exist. Both give an anodic wave at glassy carbon anodes (acetonitrile water 45/55 in 0.05 M LiClO ). The trans form is oxidized with E +1.05 V whereas cis with E = +1.02V. ... 

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