Muscle resistance

Jarajapu YPR, Coats P, McGrath JC, Hillier C, MacDonald A. Functional characterization of aj-adrenoceptor subtypes in human skeletal muscle resistance arteries. BrJ Pharmacol 2001 133 679-686. 

Jarajapu YPR, Macdonald A, Hillier C, McGrath JC, Mackenzie JF, Daly CJ. Quantitative imaging of QAPB-associated fluorescence in smooth muscle cells from human skeletal muscle resistance arteries. Br J Pharmacol 2002 135 303P. 

J.R. Faick, and J.H. Lombard (2001). Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries. J. Hisc. Res. 38, 305-314. 

Frisbee JC, Roman RJ, Falck JR, Krishna UM, Lombard JH (2001) 20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats. Microcirculation 8 45-55... 

The classic condition in humans arising from a deficiency of vitamin C is scurvy, characterised by oedema, emaciation and diarrhoea. Failure in collagen formation results in structural defects in bone, teeth, cartilage, connective tissues and muscles. Resistance to infection is reduced. 

Muscle resistivity pm) at 5 kHz was calculated using the formula applied to cylinders... 

Our resistivity results are comparable with those reported in the literature [21,22], In the meta-analysis by [22], for instance, the 95% confidence interval for skeletal muscle resistivity was 1,55-3,72 Q m. [23] reported an average resistivity at zero frequency of five muscles for both sexes and all ages of 2 0,19 ohm m. 

Aldrich TK, Karpel JP, Uhrlass RM, et al. Weaning from mechanical ventilation adjunctive use of inspiratory muscle resistive training. Crit Care Med 1989 17(2) 143-147. 

Figure 5 Respiratory muscle resistive training with threshold loading in a patient weaning from mechanical ventilation.

Amiodarone dilates arteriolar vascular smooth muscle, especiady coronary arteries, and thus exhibits antianginal effects. Its effects on the peripheral vasculature to decrease resistance leads to a decrease in left ventricular stroke work and a decrease in myocardial oxygen consumption. The dmg rarely produces hypotension that requires discontinuation of the dmg (1,2). 

Calcium channel blockers reduce arterial blood pressure by decreasing calcium influx, resulting in a decrease in intracellular calcium (236,237). The arterial smooth muscle tone decreases, thereby decreasing total peripheral resistance. The increase in vascular resistance in hypertension is found to depend much on calcium influx. Calcium channel blockers reduce blood pressure at rest and during exercise. They decrease the transmembranous calcium influx or entry that lead to a net decrease of intracellular calcium and therefore the vascular tone falls, as does blood pressure. 

Nasal vasculature may offer some insight into this question, though research to date has been equivocal. Nasal turbinate vessels can be classified as either capacitance vessels or resistive vessels. Capacitance vessels appear to vasodilate in response to infection while resistance vessels appear to respond to cold stimuli by vasoconstriction. Buccal vascular structures also respond to thermal stimuli but appear to respond principally to cutaneous stimuli. How pharyngeal and tracheobronchial submucosal vessels react to thermal stimuli is not known, though cold-induced asthma is believed to result from broncho-spasms caused by susceptible bronchial smooth muscle responding to exposure to cold dry air.- This asthmatic response suggests an inadequate vascular response to surface cooling. 

Vasoconstrictor. A drug that causes a contraction of the vascular smooth muscle, thus increasing the resistance to blood flow. 

Sorcin (soluble resistance-related calcium binding protein) was isolated from multidrug-resistant cells and is expressed in a few mammalian tissues such as skeletal muscle, heart, and brain. In the heart, sorcin interacts with the ryanodine receptor and L-type Ca2+-channels regulating excitation in contraction coupling. 

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